Title Page
Contents
I. Introduction 6
II. Methods and Materials 8
Materials 8
Statistical analysis 9
III. Results 10
Patients characteristics 10
Treatment modalities 12
Analysis of the prognosis factors and the survival rate 13
IV. Discussions 18
V. References 23
VI. Abstracts 26
Table. 1. Baseline characteristics of the patients 11
Table. 2. Univariate analysis of overall survival 15
Table. 3. Multivariate analysis of possible prognostic factors 16
Table. 4. Differences in clinical parameters according to primary tumor resection or not 16
Fig. 1. Kaplan-Meire estimates of overall survival according to primary tumor resection (A), CEA level (B), gender (C), and level of AST (D) in elderly stage IVB colorectal cancer. 14