This study offered analytic framework to measure the direct and indirect economic effect of an international conference. Then, it applied the framework to the Korea-ASEN Commemorative Summit, which was held in Jeju in 2009. AHP, Regression Analysis Model and Multi Region Input-Output Model were used to measure the economic impact of the conference on the Juju economy. Results showed that the expenditure that was spent by the participants of the conference generated 6,387 million won output, 3,357 million won value added, and 75 jobs. Results also indicated that the investment of the conference organizer generated 49,231 million won output, 23,604 value added, and 539 jobs. Moreover, results demonstrated that the conference significantly raised the attractiveness of Jeju as an international conference destination.