This study was performed to investigate the wound healing effects of Allium cepa L. on Staphylococcus
intermedius contaminated wound. 4 full-thickness skin wounds (2 cm ?2 cm) were made in the back and Staphylococcus
intermedius was inoculated in seven dogs. In each dog, the wounds were treated with onion extract (experimental
group) and normal saline (control group), respectively. The wound contraction rate of the experimental group was
higher than that of the control group during the experimental period. The occupation rate showed that the wounds
of the experimental groups contracted more vigorously than that of the control group in the early period of wound
healing. The mean value of tensile strength on the 22 day after wounding was 4,741 ?848 g/cm2 in the experimental
group and 2,400 ?397 g/cm2 in the control group. The number of S. intermedius in the experimental groups was
decreased more rapidly than that of the control group. These results suggest that application of activated onion extract
in like full-thickness skin wounds promote wound healing.