The drug-eluting stent coating film (PTX-Eluting PTFE film) was investigated by using poly(lactic-co-glycolic acid) (PLGA) and poly L-lactic acid (PLLA) via dip coating technique and characterized by thickness, drug eluting test, contact angle, proliferation of smooth muscle cell (SMC). The thickness of the films in ranged from 0.039 μm to 0.045 μm according to the composition of PLGA and PLLA. The sustained release behavior of paclitaxel (PTX) was observed for 65 days at PLGA:PLLA (3:7) film. The surface degradation behavior of the film exposed for 65 days in PBS buffer depends on the ration of PLLA. For monitoring of restenosis, the attachment and proliferation of SMC on the film was observed by fluorescence microscopy. The attachment and proliferation of SMC increase with increasing of PLLA content. It means that the hydrophilic property of the film surface leads to suppress the attachment and proliferation of SMC.