The purpose of this study was to identify the relationships between leisure attitude and depression of yoga exercise participants. The subjects for this study totalled 312 yoga exercise participants over 20 years old female by purposive sampling in D city. Instruments of this study were used scales Leisure Attitude Scale(LAS) and Depression Scale. Its validity and reliability were verified by factor analysis and reliability check. The collected data were analyzed by descriptive statistics, correlation analysis and multiple regression analysis using SPSS 18.O statistics package. The following conclusions were drawn. First, there were differences in leisure attitude of yoga exercise participants but no differences in depression. Second, there were negative relationships between leisure attitude and depression of yoga exercise participants. Third, the leisure attitude of yoga exercise participants had an negative effect on depression.