In this study, we prepared lip-gloss containing punica granatum flower extract and evaluated the stability, safety, and usability. For stability evaluation, centrifugation test, heat-cool cycling werw performed as well as changes in pH and viscosity and pHwere measured for 8 weeks. After applying the lip-gloss, a skin patch test was performed to identify the occurrence of erythema on the patch area in accordance with the conventional ICDRG guidelines. Measured via a 5-point Likert type scale, the degree of satisfaction derived from actual consumption was rated. In terms of the stability of physical and chemical properties, the control, sample A and sample B were noted to be stable. No skin reactions were observed in the groups of control, sample A, and sample B. Moreover, while the value of heat sensation were highest in sample A, the highest user satisfaction in functionality, volume and practicality were reported by sample B. The overall findings draw a conclusion that sample B gained most prominence and satisfaction through the sensory evaluation. For that reason, this study accentuates that lip-gloss containing punica granatum flower extract is highly promising with a great potential for commercialization.