The purpose of this study was to analyze the effect of meta-cognition on the relationship between tourism-related majors students on major learning commitment and career decision-making self-efficacy, to verify the mediating effect of major learning commitment, and to provide basic academic materials for enhancing competency in education by analyzing the difference between the two groups of males and females through a t-test. The study was conducted from January 1st to January 31st, 2021 using SPSS V. 21.0 on 272 tourism related major students in Korea. The results of the study showed that meta-cognition had a significant positive (+) effect on major learning commitment and career decision-making self-efficacy, and major learning commitment had a mediating effect, and as a result of analyzing the differences between the groups of males and females, there was a difference. According to these results, it can be determined that effective learning strategies are required to increase career opportunities and choices. This can be done by increasing the levels of academic achievement through the necessity of pre-learning and motivation for tourism related major students.