title page
Abstract
SUMMARY
Contents
1. Introduction 31
2. Context and Current Status of the Program 35
TECHNOLOGY 36
Dynamic Imaging Platform Group 36
Cell Biophysics 43
Discovery Cell Biology 53
Screening Technology & Pharmacology 62
Image Mining 71
Diagonostics 77
CHEMISTRY 87
Nano/Biochemistry 87
Medicinal Chemistry 102
BIOLOGY 103
Biology of Intracellular Pathogens Group 103
Systems Biology of Pathogens 108
Cell Biology of Retroviruses 119
Innate Immunology 133
CONSIGNED RESEARCH PROJECTS 135
3. References 154