표제지
목차
주제 1. TSE 진단 및 시료채취요령 / 손현주 4
BSE 진단체계 6
CWD, Scrapie 진단체계 7
검역원으로 송부될 시료 7
Comparison of RPLN and obex in deteion of CWD 8
Sheep and Goat population Statistics 9
Whole brain techinique(1) 10
Whole brain techinique(2) 10
Whole brain techinique(3) 11
Spatula technique(1) 11
Spatula technique(2) 12
Collection of Retropharyngeal LN(1) 12
Collection of Retropharyngeal LN(2) 13
Collection of Retropharyngeal LN(3) 13
Collection of Retropharyngeal LN(4) 14
BSE : Sample collection 15
Sample collection : FLOW CHART 15
The obex region 16
Detection of PrP-res : IHC(BSE) 16
Detection of PrP-res : IHC(CWD, Scrapie) 17
Western Blotting 17
Inappropriate Sample collection 18
Diagnostic : Rapid tests(BSE) 19
Result Interpretation 21
The Combination of Tests 22
Atypical BSE (개요) 23
Atypical BSE (가설) 23
Molecular profile of Atypical BSE 24
Atypical BSE (Italy) 24
비정형 BSE의 방역정책과 진단 26
주제 2. 2010년 TSE 정밀검사 실시요령 / 이윤희 28
우리나라 TSE 예찰 절차 31
농식품부 가축방역사업 계획 실시요령 32
2010년 TSE 예찰 및 정밀검사 세부요령 33
축가법상 기립불능소 40
축가법상 기립불능소 (1) 40
축가법상 기립불능소 (2) 41
축가법상 기립불능소 (3) 41
축가법상 기립불능소 (4) 42
BSE SOP, TSE SOP 등 각종참고자료 42
우리나라 "BSE 위험통제국" 지위 획득 후 변화 44
2010년 TSE 예찰 동향 46
BSE Surveillance Results in the ROK 46
OIE points achieved for last 7 years 47
2010.1-9월 시·도별 BSE 예찰실적 분석(1) 47
2010.1-9월 시·도별 BSE 예찰실적 분석(2) 48
2010.1-9월 시·도별 BSE 예찰실적 분석(3) 48
Downer Cows - OIE points achieved since November 2009 49
CWD surveillance results (Sep.2010) 49
Scrapie surveillance results (Sep.2010) 50
주제 3. 우리나라 BSE 위험통제국 지위 획득 사례 / 조인수 52
우리나라 "BSE 위험통제국" 지위 획득(2010. 5. 27) 55
그간 추진 내역 55
OIE BSE 예찰 및 지위등급평가 기준 57
OIE Code - previously 58
OIE Code - present(1) 58
OIE Code - present(2) 59
BSE status recognition by OIE 60
OIE BSE risk status categorization 60
Questionaire - Section 3 (1) 61
Questionaire - Section 3 (2) 61
Questionaire - Section 3 (3) 62
BSE status of OIE member countries (as May 27 2010) 62
BSE risk status of OIE Members (as by May 2010) 63
우리나라"BSE 위험통제국" 지위 유지 방향 63
OIE official procedures and policy for Members wishing to apply for recognition of animal disease status 64
OIE Code Article 11.6.22 (1) 65
BSE 예찰 : 향후 추진 방향? 65
주제 4. Statistical Concepts of Animal Health Surveillance for BSE / 박선일 68
Any differences between them? 71
Surveillance 71
Monitoring vs. Surveillance 72
From disease control program perspectives: MOSS 72
Specifying goals and objectives 73
OIE guidelines on BSE 75
Point targets depend on population size 75
Surveillance points by subpopulation 76
Questions? 76
Sampling design 77
Critical factors considered in SS calculation 79
Q1: Why risk-based surv.? 80
Q2: Why differnt surveillance points by age? 83
Q3: Why different surveillance streams? 85
Q4: Why 7 years in cumulative points? 86
Q5: why point-based system & point values based on what? Sample size & Power 87
The importance of SS 87
Error and power 89
Understanding power 95
Factors affecting power 96
Which factors to handle... 98
Q5: No. of animals tested (Sample size) 99
Future challenge... 108
주제 5. Chronic Wasting Disease outbreaks and suveillance program in the Republic of Korea / 손현주 110
What is Chronic Wasting Disease? 112
History of CWD 113
Origin of CWD 113
Geographical distribution of CWD 114
Susceptible Hosts (1) 114
Host range of CWD 115
Clinical signs of CWD (1) 115
Clinical signs of CWD (2) 116
CWD surveillance program 117
National Reference Laboratory on CWD 117
Cervidae population in the RO Korea 118
Cervidae population statistics (1) 118
Cervidae population statistics (2) 119
CWD outbreak situation in 2001 119
CWD outbreak situation in 2004 120
CWD outbreak situation in 2005 120
Control Measures 121
Differential Diagnosis of CWD suspects 122
Chronology of CWD diagnosis 123
Setting up of CWD diagnoisis 123
CWD Surveillance Program 124
CWD surveillance data since 2001 125
CWD outbreaks in July of 2010 125
CWD outbreak situation in 2010 126
CWD outbreaks in ROK 127
Further CWD control strategies(1) 127
Further CWD control strategies(2) 128
Acknowledgements 128
판권기 130