IntroductionPart I Balancing Individual and Collective Interests“Strictly Biomedical? Sketching the Ethics of the Big Data Ecosystem in Biomedicine”Using Transactional Big Data for Epidemiological Surveillance: Google Flu Trends and Ethical Implications of ‘Infodemiology’Denmark at a Crossroad? Intensified Data Sourcing in a Research Radical CountryA Critical Examination of Policy-Developments in Information Governance and the BiosciencesPart II Privacy and Data ProtectionMany Have It Wrong – Samples Do Contain Personal Data: The Data Protection Regulation as a Superior Framework to Protect Donor Interests in Biobanking and Genomic ResearchWhat’s Wrong with the Right to Genetic Privacy: Beyond Exceptionalism, Parochialism and Adventitious EthicsPart III ConsentHow Data Are Transforming the Landscape of Biomedical Ethics: The Need for ELSI Metadata on ConsentOn the Compatibility of Big Data Driven Research and Informed Consent: The Example of the Human Brain ProjectPart IV Ethical GovernanceBig Data Governance: Solidarity and the Patient VoicePremises for Clinical Genetics Data Governance: Grappling with Diverse Value LogicsState Responsibility and Accountability in Managing Big Data in Biobank Research: Tensions and Challenges in the Right of Access to DataBig Data, Small Talk: Lessons from the Ethical Practices of Interpersonal Communication for the Management of Biomedical Big DataPart V Professionalism and Ethical DutiesResearchers’ Duty to Share Pre-publication Data: From the Prima Facie Duty to PracticeReporting and Transparency in Big Data: The Nexus of Ethics and MethodologyCreating a Culture of Ethics in Biomedical Big Data: Adapting ‘Guidelines for Professional Practice’ to Promote Ethical Use and Research PracticePart VI ForesightThe Ethics and Politics of Infrastructures: Creating the Conditions of Possibility for Big Data in MedicineEthical Reuse of Data from Health Care: Data, Persons and InterestsThe Ethics of Big Data: Current and Foreseeable Issues in Biomedical Contexts