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기사명/저자명
Intracellular uptake of magnetite nanoparticles conjugated with RGDS-peptide / Zhi-Cai Xing, Min-Jeong Park, Seung-Jin Han, Inn-Kyu Kang, Moon-Jeong Choi, Byung-Heon Lee, Yongmin Chang 인기도
발행사항
Seoul : The Polymer Society of Korea, 2011.09.25
수록지명
Macromolecular research. vol. 19 no. 9 (Sep. 2011), pp.897-903
자료실
[서울관] 정기간행물실(524호)  도서위치안내(서울관)
외부기관 원문
외부기관 원문
제어번호
KINX2011114854
원문

초록보기 더보기

Peptides containing the Arg-Gly-Asp (RGD) motif inhibit cell adhesion and exhibit a range of other biological

effects including anticoagulant and antimetastatic activities. This study examined the anchorage independent

effects of an RGD-containing peptide, Arg-Gly-Asp-Ser (RGDS), on NIH 3T3 fibroblasts. Magnetite nanoparticles were

prepared by the coprecipitation of ferrous iron (Fe^2+) and ferric iron (Fe^3+) with NH4OH and dextran (DNPs). The

aminosilane agent of 3-aminopropyltriethoxysilane (A) is considered to be a candidate for modification of the surface

of magnetite nanoparticles (ADNPs). The amino-functionalized magnetite nanoparticles were activated using

the glutaraldehyde (G) method (GADNPs). Subsequently, RGD or RGDS peptides were immobilized on the glutaraldehyde-

modified magnetite nanoparticles (RGADNPs or RSGADNPs). The RSGADNPs were evaluated using

Fourier-transform infrared (FTIR) spectroscopy, transmission electron microscopy (TEM), and dynamic light scattering

(DLS). The biological responses of the RSGADNPs were evaluated using NIH 3T3 fibroblast cells. Inductively

coupled plasma mass spectrophotometry (ICP-MS) and Prussian blue staining showed that the RSGADNPs

were internalized into the NIH 3T3 cells compared to the RGADNPs. These results suggest that RSGADNP may

find ever-growing applications in biological labels and detection or contrast agents in life science and medical diagnostics.

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참고문헌 (29건) : 자료제공( 네이버학술정보 )더보기

참고문헌 목록에 대한 테이블로 번호, 참고문헌, 국회도서관 소장유무로 구성되어 있습니다.
번호 참고문헌 국회도서관 소장유무
1 Purification of intracellular compartments involved in antigen processing: a new method based on magnetic sorting 네이버 미소장
2 Synthesis of monodisperse nanoparticles of barium titanate: toward a generalized strategy of oxide nanoparticle synthesis. 네이버 미소장
3 Reverse Micelle Synthesis and Characterization of Superparamagnetic MnFe~2O~4 Spinel Ferrite Nanocrystallites 네이버 미소장
4 A general strategy for nanocrystal synthesis 네이버 미소장
5 Magnetic glyco-nanoparticles: a tool to detect, differentiate, and unlock the glyco-codes of cancer via magnetic resonance imaging. 네이버 미소장
6 Surface modification of magnetite nanoparticles using lactobionic acid and their interaction with hepatocytes 네이버 미소장
7 Nano Lett.. Vol. 2. pp. 575 미소장
8 Evaluation of L929 fibroblast attachment and proliferation on Arg-Gly-Asp-Ser (RGDS)-immobilized chitosan in serum-containing/serum-free cultures 네이버 미소장
9 The influence of transferrin stabilised magnetic nanoparticles on human dermal fibroblasts in culture 네이버 미소장
10 Proceedings of the 30th Annual Symposium of Controlled Release of Bioactive Materials. Vol. 30. pp. 788 미소장
11 Receptor-mediated targeting of magnetic nanoparticles using insulin as a surface ligand to prevent endocytosis. 네이버 미소장
12 Synthesis and surface engineering of iron oxide nanoparticles for biomedical applications 네이버 미소장
13 Evidence for receptor-mediated hepatic uptake of pullulan in rats 네이버 미소장
14 Elastin: molecular description and function. Vol. 31. pp. 261 미소장
15 Surface modification of magnetites using maltotrionic acid and folic acid for molecular imaging 소장
16 Surface Modification of Magnetite Nanoparticles with Doxorubicin and RGD Peptide and their Biomedical Application 네이버 미소장
17 (Carboxymethyl)chitosan-modified superparamagnetic iron oxide nanoparticles for magnetic resonance imaging of stem cells. 네이버 미소장
18 Immunospecific ferromagnetic iron-dextran reagents for the labeling and magnetic separation of cells 네이버 미소장
19 RGD modified polymers: biomaterials for stimulated cell adhesion and beyond 네이버 미소장
20 Surface modifications of ZnO quantum dots for bio-imaging 네이버 미소장
21 Synthesis and characterization of micron-sized monodisperse superparamagnetic polymer particles with amino groups 네이버 미소장
22 The biological chemistry of folate receptors 네이버 미소장
23 Synthesis and Characterization of Spherical Magnetite/Biodegradable Polymer Composite Particles 네이버 미소장
24 In vivo magnetic resonance imaging of transgene expression 네이버 미소장
25 Magnetic and hydrogel composite materials for hyperthermia applications 네이버 미소장
26 Synth. React. Inorg. Met.-Org. Nano-Metal Chem.. Vol. 38. pp. 204 미소장
27 Cytotoxicity suppression and cellular uptake enhancement of surface modified magnetic nanoparticles 네이버 미소장
28 Surface-modified magnetite nanoparticles for hyperthermia: Preparation, characterization, and cytotoxicity studies 네이버 미소장
29 Dextran and albumin derivatised iron oxide nanoparticles: influence on fibroblasts in vitro. Vol. 24. pp. 4551 미소장

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