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기사명/저자명
Sea lettuce(Ulva fasciata) extract has an inhibitory effect on proinflammatory cytokine pro-duction in CpG-stimulated bone marrow-derived macrophages and dendritic cells / Zahid Manzoor, Sohyun Kim, Doobyeong Chae, Eun-Sook Yoo, Hee-Kyoung Kang, Jin-Won Hyun, Nam Ho Lee, In Soo Suh, Young-Sang Koh 인기도
발행사항
Seoul : Korean Society of Food Science and Technology, 2013.06.30
수록지명
Food science and biotechnology. vol.22 no.3 (Jun 2013), pp.781-786
자료실
[서울관] 정기간행물실(524호)  도서위치안내(서울관)
외부기관 원문
외부기관 원문
제어번호
KINX2013132007
주기사항
Sea lettuce extract has an inhibitory effect on pro-inflammatory cytokine production in CpG-stimulated bone marrow-derived macrophages and dendritic cells
원문

초록보기 더보기

This report was designed to study inhibitory effect of sea lettuce (Ulva fasciata) extract (UFE) on proinflammatory cytokine production in bone marrow-derived macrophages (BMDM) and dendritic cells (BMDC). The UFE (0-50 μg/mL) pre-treatment showed a dose dependant inhibitory effect on interlukin (IL)-12 p40, IL-6, and tumor necrosis factor (TNF)-α productions in CpG-stimulated BMDMs and BMDCs as compared to non-treated controls. The UFE pre-treatment exhibited strong inhibitory effect on the phosphorylation of p38 mitogen-activated protein kinase (MAPK) while it showed moderate inhibition on nuclear factor (NF)-κB activation as indirectly evaluated by degradation of IκBα. In activator protein (AP)-1 and NF-κB reporter gene assay, the UFE pre-treatment showed moderate inhibitory effect on both AP-1- and NF-κBdependent reporter gene activities. Thus, these results suggest that inhibitory effect of UFE on pro-inflammatory cytokine production may correlate with partial inhibition of both AP-1 and NF-κB pathways. Hence, our data warrant further studies concerning potentials of sea lettuce for medicinal food.

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참고문헌 (25건) : 자료제공( 네이버학술정보 )더보기

참고문헌 목록에 대한 테이블로 번호, 참고문헌, 국회도서관 소장유무로 구성되어 있습니다.
번호 참고문헌 국회도서관 소장유무
1 Toll-like receptor signalling 네이버 미소장
2 Nucleic Acid Recognition and Signaling by Toll-like Receptor 9: Compartment-dependent Regulation 네이버 미소장
3 Mitogen activated protein (MAP) kinase signal transduction pathways and novel anti-inflammatory targets. 네이버 미소장
4 Mitogen-Activated Protein Kinase Pathways Mediated by ERK, JNK, and p38 Protein Kinases 네이버 미소장
5 Antioxidant activity of Hawaiian marine algae. 네이버 미소장
6 Physiological and physico-chemical characterization of dietary fibre from the green seaweed Ulva fasciata Delile. 네이버 미소장
7 Immunomodulatory potential of marine secondary metabolites against bacterial diseases of shrimp. Vol. 230. pp. 241 미소장
8 Biopotentials of Ulva Fasciata and Hypnea Musciformis Collected from the Peninsular Coast of India 네이버 미소장
9 In vitro antioxidant and antimicrobial activities of two Hawaiian marine Limu : ulva fasciata(Chlorophyta) and Gracilaria salicornia(Rhodophyta) 소장
10 Intracellular invasion of Orientia tsutsugamushi activates inflammasome in asc-dependent manner. 네이버 미소장
11 Mitogen-activated protein kinases and tumor necrosis factor alpha responses of macrophages infected with Orientia tsutsugamushi 네이버 미소장
12 Toll-like receptors. 네이버 미소장
13 A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. 네이버 미소장
14 Host Innate Immune Receptors and Beyond: Making Sense of Microbial Infections 네이버 미소장
15 Interleukin-15 mediates T cell-dependent regulation of tumor necrosis factor-alpha production in rheumatoid arthritis. 네이버 미소장
16 The p38 MAP kinase pathway as a therapeutic target in inflammatory disease 네이버 미소장
17 ERK and p38 MAPK-Activated Protein Kinases: a Family of Protein Kinases with Diverse Biological Functions 네이버 미소장
18 TRANSCRIPTIONAL AND POST-TRANSCRIPTIONAL CONTROL OF GENE EXPRESSION IN INFLAMMATION 네이버 미소장
19 The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors 네이버 미소장
20 Toll-like Receptors and Innate Immunity 네이버 미소장
21 Dendritic cells and the control of immunity. 네이버 미소장
22 The Nature of the Principal Type 1 Interferon-Producing Cells in Human Blood 네이버 미소장
23 Pattern Recognition Receptors and Inflammation 네이버 미소장
24 A Toll-like receptor recognizes bacterial DNA 네이버 미소장
25 Spatiotemporal regulation of MyD88–IRF-7 signalling for robust type-I interferon induction 네이버 미소장
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