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Purpose: Functional mitral regurgitation (FMR) and myocardial dyssynchrony commonly occur in patients with dilated cardiomyopathy (DCM). The aim of this study was to elucidate changes in FMR in relation to those in left ventricular (LV) dyssynchrony as well as geometric parameters of the mitral valve (MV) in DCM patients during dobutamine infusion. Materials and Methods: Twenty-nine DCM patients (M:F=15:14; age: 62±15 yrs) with FMR underwent echocardiography at baseline and during peak dose (30 or 40 ug/min) of dobutamine infusion. Using 2D echocardiography, LV end-diastolic volume, end-systolic volume (LVESV), ejectionfraction (EF), and effective regurgitant orifice area (ERO) were estimated. Dyssynchronyindices (DIs), defined as the standard deviation of time interval-to-peak myocardial systolic contraction of eight LV segments, were measured. Using the multi-planar reconstructive mode from commercially available 3D image analysis software, MV tenting area (MVTa) was measured. All geometrical measurements were corrected (c) by the height of each patient. Results: During dobutamine infusion,EF (28±8% vs. 39±11%, p=0.001) improved along with significant decrease in cLVESV (80.1±35.2 mm3/m vs. 60.4±31.1 mm3/m, p=0.001); cMVTa (1.28±0.48 cm2/m vs. 0.79±0.33 cm2/m, p=0.001) was significantly reduced; and DI (1.31±0.51 vs. 1.58±0.68, p=0.025) showed significant increase. Despite significant deteriorationof LV dyssynchrony during dobutamine infusion, ERO (0.16±0.09 cm2 vs. 0.09±0.08 cm2, p=0.001) significantly improved. On multivariate analysis, ΔcMVTa and ΔEF were found to be the strongest independent determinants of ΔERO (R2=0.443, p=0.001). Conclusion: Rather than LV dyssynchrony, MV geometry determined by LV geometry and systolic pressure, which represents the MV closing force, may be the primary determinant of MR severity.

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The Role of Carotid Ultrasound for Cardiovascular Risk Stratification beyond Traditional Risk Factors 박성하, 이찬주 pp.551-557

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Whole Blood Interferon-γ Release Assay Is Insufficient for the Diagnosis of Sputum Smear Negative Pulmonary Tuberculosis 장윤수, 박희진, 신정아, 김형중, 안철민 pp.725-731

Diagnostic Yield of Bronchial Washing Fluid Analysis for Hemoptysis in Patients with Bronchiectasis 이세원, 박주희, 김수정, 이애라, 김정현, 임효정, 조영재, 박종선, 윤호일, 이춘택, 이재호, 이중규 pp.739-745

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Changes in Dynamic Pedobarography after Extensive Plantarmedial Release for Paralytic Pes Cavovarus 박건보, 권용욱, 김현우, 황진호, 박훈, 박희완 pp.766-772

Unrecognized Kinetics of Serum Testosterone : Impact on Short-Term Androgen Deprivation Therapy for Prostate Cancer 정병하, 구교철, 이동훈, 김규현, 이승환, 홍창희, 홍성준 pp.570-575

The Prevalence of Idiopathic Scoliosis in Eleven Year-Old Korean Adolescents: A 3 Year Epidemiological Study 박문수, 이진영, 문성환, 김한조, 서보경, 남지훈, 정재균, 이환모 pp.773-778

Expression of Glycolysis-Related Proteins in Solid Papillary Carcinoma of the Breast According to Basement Membrane Status 구자승, 권지은, 정우희 pp.576-583

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Separate Vertical Wiring for the Fixation of Comminuted Fractures of the Inferior Pole of the Patella 양규현, 송형근, 유제현, 변영수 pp.785-791

Antiplatelet Effect of Clopidogrel Can Be Reduced by Calcium-Channel Blockers 이경열, 서권덕, 김영대, 윤영원, 김종윤 pp.683-688

Response of Functional Mitral Regurgitation during Dobutamine Infusion in Relation to Changes in Left Ventricular Dyssynchrony and Mitral Valve Geometry 권준, 최웅길, 김수현, 김수한, 박상돈, 백영수, 신성희, 우성일, 김대혁, 박금수 pp.592-598

Aggravation of Hypertriglyceridemia and Acute Pancreatitis in a Bipolar Patient Treated with Quetiapine Fone-Ching Hsiao, Li-Syue Liou, Yi-Jen Hung, Chang-Hsun Hsieh pp.831-833

Multidetector Computed Tomography for the Evaluation of Coronary Artery Disease : The Diagnostic Accuracy in Calcified Coronary Arteries, Comparing with IVUS Imaging 이병권, 박종관, 김종윤, 권혁문, 김태훈, 오승진, 홍범기, 윤영원, 민필기, 권성우 pp.599-605

Sex Differences in Remifentanil Requirements for Preventing Cough during Anesthetic Emergence 이정림, 소사라, 박윤곤, 강상욱, 이보라 pp.807-814

Blastocyst Transfer Ameliorates Live Birth Rate Compared with Cleavage-Stage Embryos Transfer in Fresh In Vitro Fertilization or Intracytoplasmic Sperm Injection Cycles : Reviews and Meta-Analysis Hai-Xiang Sun, Shan-Shan Wang pp.815-825

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Ibuprofen Associated Acute Vanishing Bile Duct Syndrome and Toxic Epidermal Necrolysis in an Infant 박재홍, 김혜영, 양혜경, 김성헌 pp.834-837

COPD Patients with Exertional Desaturation Are at a Higher Risk of Rapid Decline in Lung Function 김동규, 김창환, 박용범, 박소영, 박성훈, 김철홍, 박상면, 이명구, 현인규, 정기석 pp.732-738

Comparison of Bioabsorbable Suture Anchor Fixation on the Tibial Side for Anterior Cruciate Ligament Reconstruction Using Free Soft Tissue Graft : Experimental Laboratory Study on Porcine Bone 김명구, 나석인, 이종민, 박주용 pp.760-765

Histogram Analysis of Hepatobiliary Phase MR Imaging as a Quantitative Value for Liver Cirrhosis : Preliminary Observations 최진영, 김한솔, Mark Sun, Claude B. Sirlin pp.651-659

Development of a Quantitative Sandwich Enzyme-Linked Immunosorbent Assay for Detecting the MPT64 Antigen of Mycobacterium tuberculosis 전보영, 지미정, 조병기, 조영식, 박송용, 조상내, 윤병수 pp.746-752

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Delta Neutrophil Index as an Early Marker for Differential Diagnosis of Adult-Onset Still's Disease and Sepsis 이상원, 박희진, 하유정, 표정윤, 박용범, 이수곤 pp.753-759

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The Role of Insulin Resistance in Diabetic Neuropathy in Koreans with Type 2 Diabetes Mellitus: A 6-Year Follow-Up Study 최영철, 조유나, 이기욱, 정주리, 박형준, 김승민, 신하영, 홍지만, 안철우 pp.700-708

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Comparison of Full Lesion Coverage versus Spot Drug-Eluting Stent Implantation for Coronary Artery Stenoses 홍명기, 김승환, 윤경호, 강웅철, 신동호, 김중선, 김병극, 고영국, 최동훈, 장양수 pp.584-591

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참고문헌 (27건) : 자료제공( 네이버학술정보 )

참고문헌 목록에 대한 테이블로 번호, 참고문헌, 국회도서관 소장유무로 구성되어 있습니다.
번호 참고문헌 국회도서관 소장유무
1 Dilated cardiomyopathy with mitral regurgitation: Decreased survival despite a low frequency of left ventricular thrombus 네이버 미소장
2 Outcome after mitral valve repair for functional ischemic mitral regurgitation. 네이버 미소장
3 Effectiveness of Surgical Repair of Mitral Regurgitation Concomitant With Dilated Cardiomyopathy 네이버 미소장
4 Insights From Three-Dimensional Echocardiography Into the Mechanism of Functional Mitral Regurgitation 네이버 미소장
5 Mechanism of ischemic mitral regurgitation with segmental left ventricular dysfunction: three-dimensional echocardiographic studies in models of acute and chronic progressive regurgitation 네이버 미소장
6 Determinants of the Degree of Functional Mitral Regurgitation in Patients With Systolic Left Ventricular Dysfunction: A Quantitative Clinical Study 네이버 미소장
7 Geometric Differences of the Mitral Apparatus Between Ischemic and Dilated Cardiomyopathy With Significant Mitral Regurgitation: Real-Time Three-Dimensional Echocardiography Study 네이버 미소장
8 Myocardial asynchronism is a determinant of changes in functional mitral regurgitation severity during dynamic exercise in patients with chronic heart failure due to severe left ventricular systolic dysfunction. 네이버 미소장
9 Effect of dynamic myocardial dyssynchrony on mitral regurgitation during supine bicycle exercise stress echocardiography in patients with idiopathic dilated cardiomyopathy and 'narrow' QRS. 네이버 미소장
10 Recommendations for chamber quantification: a report from the American Society of Echocardiography's Guidelines and Standards Committee and the Chamber Quantification Writing Group, developed in conjunction with the European Association of Echocardiography, a branch of the European Society of Cardiology. 네이버 미소장
11 Effective regurgitant orifice area: A noninvasive Doppler development of an old hemodynamic concept 네이버 미소장
12 Left Ventricular Mechanics During Exercise: A Doppler and Tissue Doppler Study 네이버 미소장
13 Measures of Dyssynchrony in the Left Ventricle of Healthy Children and Young Patients with Dilated Cardiomyopathy 네이버 미소장
14 Contribution of Exercise-Induced Mitral Regurgitation to Exercise Stroke Volume and Exercise Capacity in Patients With Left Ventricular Systolic Dysfunction 네이버 미소장
15 Dynamic mitral regurgitation. An important determinant of the hemodynamic response to load alterations and inotropic therapy in severe heart failure. 네이버 미소장
16 Effect of dobutamine stress echocardiography on mitral regurgitation 네이버 미소장
17 Dynamics of functional mitral regurgitation during dobutamine therapy in patients with severe congestive heart failure: A Doppler echocardiographic study 네이버 미소장
18 Myocardial contractile reserve by dobutamine stress echocardiography predicts improvement in ejection fraction with beta-blockade in patients with heart failure: the Beta-Blocker Evaluation of Survival Trial (BEST). 네이버 미소장
19 Dobutamine-induced improvement in inferior myocardial contractile function predicts reduction in functional mitral regurgitation: a study using tissue Doppler strain rate imaging. 네이버 미소장
20 Acute effects of cardiac resynchronization therapy on functional mitral regurgitation in advanced systolic heart failure 네이버 미소장
21 A mechanism for immediate reduction in mitral regurgitation after cardiac resynchronization therapy: insights from mechanical activation strain mapping. 네이버 미소장
22 Mechanism of improvement in mitral regurgitation after cardiac resynchronization therapy 네이버 미소장
23 Impact of heart rate on mechanical dyssynchrony and left ventricular contractility in patients with heart failure and normal QRS duration 네이버 미소장
24 Different effect of exercise on left ventricular diastolic time and interventricular dyssynchrony in heart failure patients with and without left bundle branch block. 네이버 미소장
25 The effect of pharmacological stress on intraventricular dyssynchrony in left ventricular systolic dysfunction 네이버 미소장
26 Geometric changes after tricuspid annuloplasty and predictors of residual tricuspid regurgitation: a real-time three-dimensional echocardiography study 네이버 미소장
27 Geometry of the proximal isovelocity surface area in mitral regurgitation by 3-dimensional color Doppler echocardiography: Difference between functional mitral regurgitation and prolapse regurgitation 네이버 미소장

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