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Purpose: Few studies have reported on predicting prognosis using myocardial perfusion single-photon emission computed tomography (SPECT) during coronary artery disease (CAD) treatment. Therefore, we aimed to assess the clinical implications of myocardial perfusion SPECT during follow-up for CAD treatment.

Materials and Methods: We enrolled 1153 patients who had abnormal results at index SPECT and underwent follow-up SPECT at intervals ≥6 months. Major adverse cardiac events (MACE) were compared in overall and 346 patient pairs after propensity-score (PS) matching.

Results: Abnormal SPECT was associated with a significantly higher risk of MACE in comparison with normal SPECT over the median of 6.3 years (32.3% vs. 19.8%; unadjusted p<0.001). After PS matching, abnormal SPECT posed a higher risk of MACE [32.1% vs. 19.1%; adjusted hazard ratio (HR)=1.73; 95% confidence interval (CI)=1.27–2.34; p<0.001] than normal SPECT. After PS matching, the risk of MACE was still higher in patients with abnormal follow-up SPECT in the revascularization group (30.2% vs. 17.9%; adjusted HR=1.73; 95% CI=1.15–2.59; p=0.008). Low ejection fraction [odds ratio (OR)=5.33; 95% CI=3.39–8.37; p<0.001] and medical treatment (OR=2.68; 95% CI=1.93–3.72; p<0.001) were independent clinical predictors of having an abnormal result on follow-up SPECT.

Conclusion: Abnormal follow-up SPECT appears to be associated with a high risk of MACE during CAD treatment. Follow-up SPECT may play a potential role in identifying patients at high cardiovascular risk.

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기사명 저자명 페이지 원문 목차
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A Combination of Fecal Immunochemical Test Results and Iron Deficiency Anemia for Detection of Advanced Colorectal Neoplasia in Asymptomatic Men Nam Hee Kim, Mi Yeon Lee, Jung Ho Park, Dong Il Park, Chong Il Sohn, Kyuyong Choi, Yoon Suk Jung pp.910-917

Association of Inter-Arm Systolic Blood Pressure Difference with Coronary Atherosclerotic Disease Burden Using Calcium Scoring Ae-Young Her, Kyoung-Im Cho, Scot Garg, Yong Hoon Kim, Eun-Seok Shin pp.954-958

Validation of a Newly Developed Equation for Estimating Serum Apolipoprotein B : Associations with Cardiovascular Disease Surrogate Markers in Koreans Jong-Dai Kim, You-Cheol Hwang, Hong-Yup Ahn, Cheol-Young Park pp.975-980

Significance of Neutrophil-to-Lymphocyte Ratio as a Novel Indicator of Spontaneous Ureter Stone Passage Kwang Suk Lee, Jee Soo Ha, Kyo Chul Koo pp.988-993

Healthcare Costs for Acute Hospitalized and Chronic Heart Failure in South Korea : A Multi-Center Retrospective Cohort Study Hyemin Ku, Wook-Jin Chung, Hae-Young Lee, Byung-Soo Yoo, Jin-Oh Choi, Seoung-Woo Han, Jieun Jang, Eui-Kyung Lee, Seok-Min Kang pp.944-953

Impact of Follow-Up Ischemia on Myocardial Perfusion Single-Photon Emission Computed Tomography in Patients with Coronary Artery Disease Se Hun Kang, Hyo In Choi, Young-Hak Kim, Eun Young Lee, Jung-Min Ahn, Seungbong Han, Pil Hyung Lee, Jae-Hyung Roh, Sung-Han Yun, Duk-Woo Park, Soo-Jin Kang, Seung-Whan Lee, Cheol Whan Lee, Dae Hyuk Moon, Seong-Wook Park, Seung-Jung Park pp.934-943

Comparison of Multiparametric and Biparametric MRI in First Round Cognitive Targeted Prostate Biopsy in Patients with PSA Levels under 10 ng/mL Dong Hoon Lee, Jong Kil Nam, Seung Soo Lee, Ji-Yeon Han, Joon Woo Lee, Moon Kee Chung, Sung Woo Park pp.994-999

Impact of Pretreatment Hydronephrosis on the Success Rate of Shock Wave Lithotripsy in Patients with Ureteral Stone Ki Don Chang, Joo Yong Lee, Sung Yoon Park, Dong Hyuk Kang, Hyung Ho Lee, Kang Su Cho pp.1000-1005

Dr. Chang Sei Kim: A Public Health Pioneer Devoted to Korea's Independence Movement Dae Ryong Kang, Jai Keun Choi, Il Suh pp.895-898

Localization of Oncogenic Osteomalacia by Systemic Venous Sampling of Fibroblast Growth Factor 23 Ji-Yeon Lee, Hye-Sun Park, Seunghee Han, Jiyu Kelly Lim, Namki Hong, Sung Il Park, Yumie Rhee pp.981-987

Endothelial Progenitor Cells Correlated with Oxidative Stress after Mild Traumatic Brain Injury Xintao Huang, Dahai Wan, Yunpeng Lin, Naizhao Xue, Jiehe Hao, Ning Ma, Xile Pei, Ruilong Li, Wenju Zhang pp.1012-1017

Reduced Cortical Thickness in the Temporal Pole, Insula, and Pars Triangularis in Patients with Panic Disorder Eun-Kyoung Kang, Kang Soo Lee, Sang-Hyuk Lee pp.1018-1024

Physical Activity, Sedentary Habits, Sleep, and Obesity are Associated with Asthma, Allergic Rhinitis, and Atopic Dermatitis in Korean Adolescents Man-Sup Lim, Chang Hee Lee, Songyong Sim, Sung Kwang Hong, Hyo Geun Choi pp.1040-1046

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Altered Functional Connectivity of the Default Mode Network in Low-Empathy Subjects Seung Jun Kim, Sung-Eun Kim, Hyo Eun Kim, Kiwan Han, Bumseok Jeong, Jae-Jin Kim, Kee Namkoong, Ji-Woong Kim pp.1061-1065

Congenital Orbital Fibrosis : Molecular Genetic Analysis by Whole-Exome and Mitochondrial Genome Sequencing JaeSang Ko, Hyun-Joo Lee, Jin-Sung Lee, Jin Sook Yoon pp.1078-1080

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Sarpogrelate Based Triple Antiplatelet Therapy Improved Left Ventricular Systolic Function in Acute Myocardial Infarction : Retrospective Study Jae Hyuk Choi, Jung Rae Cho, Sang Min Park, Kunal Bikram Shaha, Floyd Pierres, Tserendavaa Sumiya, Kwang Jin Chun, Min-Kyung Kang, Seonghoon Choi, Namho Lee pp.959-967

Optical Coherence Tomography and Stent Boost Imaging Guided Bioresorbable Vascular Scaffold Overlapping for Coronary Chronic Total Occlusion Lesion Hu Li, Seung-Woon Rha, Cheol Ung Choi, Dong Joo Oh pp.1071-1074

Proposal Guidelines for Standardized Operating Procedures of Brain Autopsy : Brain Bank in South Korea Kyung-Hwa Lee, Sang Won Seo, Tae Sung Lim, Eun-Joo Kim, Byeong-Chae Kim, Yeshin Kim, Ho-Won Lee, Jae Pil Jeon, Sung-Mi Shim, Duk L. Na, Gi Yeong Huh, Min-Cheol Lee, Yeon-Lim Suh pp.1055-1060

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번호 참고문헌 국회도서관 소장유무
1 Shaw LJ, Hage FG, Berman DS, Hachamovitch R, Iskandrian A. Prognosis in the era of comparative effectiveness research: where is nuclear cardiology now and where should it be? J Nucl Cardiol 2012;19:1026-43. 미소장
2 Stress myocardial perfusion single-photon emission computed tomography is clinically effective and cost effective in risk stratification of patients with a high likelihood of coronary artery disease (CAD) but no known CAD 네이버 미소장
3 Fihn SD, Gardin JM, Abrams J, Berra K, Blankenship JC, Dallas AP, et al. 2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS guideline for the diagnosis and management of patients with stable ischemic heart disease: a report of the American College of Cardiology Foundation/American Heart Association task force on practice guidelines, and the American College of Physicians, American Association for Thoracic Surgery, Preventive Cardiovascular Nurses Association, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons. Circulation 2012;126:e354-471. 미소장
4 Exercise Myocardial Perfusion SPECT in Patients Without Known Coronary Artery Disease 네이버 미소장
5 Incremental prognostic value of myocardial perfusion single photon emission computed tomography for the prediction of cardiac death: differential stratification for risk of cardiac death and myocardial infarction. 네이버 미소장
6 Ischemic Burden, Treatment Allocation, and Outcomes in Stable Coronary Artery Disease 네이버 미소장
7 Comparison of the Short-Term Survival Benefit Associated With Revascularization Compared With Medical Therapy in Patients With No Prior Coronary Artery Disease Undergoing Stress Myocardial Perfusion Single Photon Emission Computed Tomography 네이버 미소장
8 Hachamovitch R, Rozanski A, Hayes SW, Thomson LE, Germano G, Friedman JD, et al. Predicting therapeutic benefit from myocardial revascularization procedures: are measurements of both resting left ventricular ejection fraction and stress-induced myocardial ischemia necessary? J Nucl Cardiol 2006;13:768-78. 미소장
9 Prognostic Impact of the Presence and Absence of Angina on Mortality and Cardiovascular Outcomes in Patients With Type 2 Diabetes and Stable Coronary Artery Disease: Results from the BARI 2D (Bypass Angioplasty Revascularization Investigation 2 Diabetes) Trial 네이버 미소장
10 Optimal medical therapy with or without percutaneous coronary intervention to reduce ischemic burden: results from the Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation (COURAGE) trial nuclear substudy. 네이버 미소장
11 Prognostic value of "routine" cardiac stress imaging 5 years after percutaneous coronary intervention: the prospective long-term observational BASKET (Basel Stent Kosteneffektivitäts Trial) LATE IMAGING study. 네이버 미소장
12 Prognostic value of stress-gated 99m-technetium SPECT myocardial perfusion imaging: Risk stratification of patients with multivessel coronary artery disease and prior coronary revascularization 네이버 미소장
13 Guidelines on the management of stable angina pectoris: executive summary: the task force on the management of stable angina pectoris of the European society of cardiology. 네이버 미소장
14 ACCF/ASNC/ACR/AHA/ASE/SCCT/SCMR/SNM 2009 Appropriate Use Criteria for Cardiac Radionuclide Imaging: A Report of the American College of Cardiology Foundation Appropriate Use Criteria Task Force, the American Society of Nuclear Cardiology, the American College of Radiology, the American Heart Association, the American Society of Echocardiography, the Society of Cardiovascular Computed Tomography, the Society for Cardiovascular Magnetic Resonance, and the Society of Nuclear Medicine. 네이버 미소장
15 Coronary Artery Disease Progression Late After Successful Stent Implantation 네이버 미소장
16 Impact of Ischemia-Guided Revascularization With Myocardial Perfusion Imaging for Patients With Multivessel Coronary Disease 네이버 미소장
17 Validation of a model of left ventricular segmentation for interpretation of SPET myocardial perfusion images 네이버 미소장
18 Standardized Myocardial Segmentation and Nomenclature for Tomographic Imaging of the Heart 네이버 미소장
19 Executive Summary: Heart Disease and Stroke Statistics—2011 Update: A Report From the American Heart Association 네이버 미소장
20 Hillis LD, Smith PK, Anderson JL, Bittl JA, Bridges CR, Byrne JG, et al. 2011 ACCF/AHA guideline for coronary artery bypass graft surgery: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. Circulation 2011;124:e652-735. 미소장
21 MatchIt: Nonparametric Preprocessing for Parametric Causal Inference 네이버 미소장
22 An initial strategy of intensive medical therapy is comparable to that of coronary revascularization for suppression of scintigraphic ischemia in high-risk but stable survivors of acute myocardial infarction. 네이버 미소장
23 Intensive medical therapy versus coronary angioplasty for suppression of myocardial ischemia in survivors of acute myocardial infarction: a prospective, randomized pilot study. 네이버 미소장
24 Prospective serial evaluation of myocardial perfusion and lipids during the first six months of pravastatin therapy: Coronary artery disease regression single photon emission computed tomography monitoring trial 네이버 미소장
25 Klocke FJ, Baird MG, Lorell BH, Bateman TM, Messer JV, Berman DS, et al. ACC/AHA/ASNC guidelines for the clinical use of cardiac radionuclide imaging--executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (ACC/AHA/ASNC Committee to Revise the 1995 Guidelines for the Clinical Use of Cardiac Radionuclide Imaging). J Am Coll Cardiol 2003;42:1318-33. 미소장
26 Ischemia Change in Stable Coronary Artery Disease Is an Independent Predictor of Death and Myocardial Infarction 네이버 미소장
27 Threshold, incidence, and predictors of prognostically high-risk silent ischemia in asymptomatic patients without prior diagnosis of coronary artery disease 네이버 미소장
28 Gibbons RJ, Abrams J, Chatterjee K, Daley J, Deedwania PC, Douglas JS, et al. ACC/AHA 2002 guideline update for the management of patients with chronic stable angina--summary article: a report of the American College of Cardiology/American Heart Association Task Force on practice guidelines (Committee on the Management of Patients With Chronic Stable Angina). J Am Coll Cardiol 2003;41:159-68. 미소장
29 Executive summary: heart disease and stroke statistics--2013 update: a report from the American Heart Association. 네이버 미소장
30 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012 네이버 미소장

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