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결과 내 검색 동의어 포함
결과 내 검색 동의어 포함

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초록보기

프로폴리스는 꿀벌에 의해 생산된 수지 물질로 벌집을 보호하기 위해 사용되어 왔다. 꿀벌은 다양한 나무와 식물에서 배출된 수분을 침과 밀랍과 섞어서 프로폴리스를 생산한다. 프로폴리스는 기원전 300년경부터 상처를 치료하는 민간요법으로 사용되어 왔다. 프로폴리스에는 플라보노이드, 페놀계 화합물, 밀랍과 같은 많은 생리 활성 화합물이 포함되어 있다. 프로폴리스의 기능적 요소들 때문에, 프로폴리스에는 생물학적 응용을 위한 넓은 스펙트럼이 있다. 프로폴리스와 프로폴리스의 생물학적 활동의 화합물은 각각 과즙의 출처와 추출 방법에 따라 달라질 수 있다. 프로폴리스의 박테리아, 바이러스, 곰팡이를 포함한 반미생물 활동이 가장 잘 알려진 특징이다. 면역조절 메커니즘의 경우 아르테필린 C와 카페인산 페네틸에스테르가 주로 조절 화합물로 확인되었으며 각 화합물은 염증 반응을 감소시키고 T 림프구에 면역억제 반응을 일으킨다. 프로폴리스는 항염증 효과를 통해 암세포 증식 억제, 종양 신호 전달 캐스케이드 차단, 항혈관신생 등 항종양 활성을 보였다. 그러나 프로폴리스의 더 많은 응용을 위해서는 과즙의 원천 분석, 프로폴리스 화합물의 식별, 프로폴리스 분자 메커니즘, 화합물 시너지 효과의 조사가 더 필요할 것으로 보인다.

Propolis is a resinous substance produced by honeybees, which they use to protect their hives. Honeybees produce propolis by mixing exudates from the various trees and plants with saliva and beeswax. It has been used since around 300 B.C. as a folk medicine to cure wounds. Propolis contains many physiologically active components, such as flavonoids, phenolic compounds, and beeswax. Because of its functional components, propolis has a wide spectrum of biological applications. The compounds in propolis and its biological activity can vary according to the location of nectar source and extraction method. Propolis is most commonly known for its anti-microorganism activity against bacteria, viruses, and fungi. Artepillin C and caffeic acid phenethyl ester (CAPE) have been identified as regulatory compounds that reduce inflammation and exert immunosuppressive reactions on T lymphocytes. Through its anti-inflammatory activity, propolis exhibits anti-tumor activity, including the inhibition of cancer cell proliferation, the blocking of tumor signaling cascades, and antiangiogenesis. However, for the more apply of propolis its analysis of nectar source, identifying of propolis compound, the molecular mechanism of propolis and the investigation of compounds synergistic effects are essential. In this study, we described the physiological activity of propolis isolated from honeybees.

권호기사

권호기사 목록 테이블로 기사명, 저자명, 페이지, 원문, 기사목차 순으로 되어있습니다.
기사명 저자명 페이지 원문 목차
Evaluation of bioassay methods to assess bacterial soft rot resistance in radish cultivars = 무 품종의 세균성 무름병 저항성 생물검정법 평가 Tania Afroz, Onsook Hur, Nayoung Ro, Jae-eun Lee, Aejin Hwang, Bichsaem Kim, Awraris Derbie Assefa, Ju Hee Rhee, Jung Sook Sung, Ho-sun Lee, Bum-Soo Hahn p. 609-616

사과 부산물의 영양성분 분석 및 항산화 효과 = Nutritional analyses and antioxidant activity of apple pomace 김지은, 신지영, 양지영 p. 617-625

제주재래흑돼지와 랜드레이스 교배 축군에서 MYH3 유전자의 6-bp 결실 변이와 육색 형질간의 연관성 분석 = Association analysis of the 6-bp deletion variant of the MYH3 gene with meat color traits in crossbred (Landrace×Jeju native black pig) pigs 강용준, 김상금, 김수연, 김민지, 김현아, 신문철, 유지현, 양병철, 조인철 p. 626-630

전립선 비대증에 대한 Houttuynia cordata Thunberg 에탄올 추출물의 최적용량 결정 = Determination of optimal dosage of ethanol extract of houttuynia cordata thunberg against benign prostatic hyperplasia 이진영, 김형회, 강재선 p. 631-640

항진균 활성, 식물 생장촉진 활성, 미네랄 가용화능을 가진 생물학적 제제로서 잠재적 식물 생장 촉진 근권세균의 특성조사 = Characterization of potential plant growth-promoting rhizobacteria as biological agents with antifungal activity, plant growth-promoting activity, and mineral solubilizing activity 이송민, 김지윤, 김희숙, 오가윤, 이광희, 이상현, 장정수 p. 641-653

Trichoderma viridescens SW-1 미백 기능성소재의 생화학적 특성 = Biochemical properties of a whitening bioactive agent derived from thrichoderma viridescens SW-1 강동우, 김판길, 김삼웅, 방규호, 김철호, 이상원, 갈상완 p. 654-661

생쥐 소장 카할세포의 pacemaker potential에서 미르타자핀 효능에 관한 연구 = Mirtazapine regulates pacemaker potentials of interstitial cells of cajal in murine small intestine 김병주 p. 662-670

Lethal (2) essential for life [l(2)efl] gene in the two-spotted cricket, gryllus bimaculatus (orthoptera: gryllidae) = 쌍별귀뚜라미(Gryllus bimaculatus)의 l(2)efl cDNA 클로닝과 발현분석 Kisang Kwon, Nuri Lee, O-Yu Kwon p. 671-676

대마 생물산업의 현황과 전망 = Current status and prospects for the hemp bioindustry 손호용, 김문년, 김영민 p. 677-685

프로폴리스의 생물학적 특성 = Biological properties of propolis isolated from honeybees 김성국, 우순옥, 장종수 p. 686-697

참고문헌 (118건) : 자료제공( 네이버학술정보 )

참고문헌 목록에 대한 테이블로 번호, 참고문헌, 국회도서관 소장유무로 구성되어 있습니다.
번호 참고문헌 국회도서관 소장유무
1 Abbasi-Parizad, P., De Nisi, P., Adani, F., Sciarria, T. P., Squillace, P., Scarafoni, A., Iametti, S. and Scaglia, B. 2020. Antioxidant and anti-inflammatory activities of the crude extracts of raw and fermented tomato pomace and their correlations with aglycate-polyphenols. Antioxidants 9, 179. 미소장
2 Ahn, M. R., Kunimasa, K., Ohta, T., Kumazawa, S., Kamihira, M., Kaji, K., Uto, Y., Hori, H., Nagasawa, H. and Nakayama, T. 2007. Suppression of tumor-induced angiogenesis by Brazilian propolis: major component artepillin C inhibits in vitro tube formation and endothelial cell proliferation. Cancer Lett. 252, 235-243. 미소장
3 Albukhari, A. A., Gashlan, H. M., El-Beshbishy, H. A., Nagy, A. A. and Abdel-Naim, A. B. 2009. Caffeic acid phenethyl ester protects against tamoxifen-induced hepatotoxicity in rats. Food Chem. Toxicol. 47, 1689-1695. 미소장
4 Alday, E., Valencia, D., Carreno, A. L., Picerno, P., Piccinelli, A. L., Rastrelli, L., Robles-Zepeda, R., Hernandez, J. and Velazquez, C. 2015. Apoptotic induction by pinobanksin and some of its ester derivatives from Sonoran propolis in a B-cell lymphoma cell line. Chem. Biol. Interact. 242, 35-44. 미소장
5 Aliyazicioglu Y., Demir, S., Turan, I., Cakiroglu, T. N., Akalin, I., Deger, O. and Bedir, A. 2011. Preventive and protective effects of Turkish propolis on H2O2 induced DNA damage in foreskin fibroblast cell lines. Acta. Biol. Hung. 62, 388-396. 미소장
6 Almeida, E. C. and Menezes, H. 2002. Anti-inflammatory activity of propolis extracts: a review. J. Venom. Anim. Toxins 8, 191-212. 미소장
7 Ansorge, S., Reinhold, D. and Lendeckel, U. 2003. Propolis and some of its constituents down-regulate DNA synthesis and inflammatory cytokine production but induce TGF-1production of human immune cells. Z. Naturforsch. C. J. Biosci. 58, 580-589. 미소장
8 Bag, A. and Chattopadhyay, R. R. 2017. Synergistic antibacterial and antibiofilm efficacy of nisin in combination with p-coumaric acid against food-borne bacteria Bacillus cereus and Salmonella typhimurium. Lett. Appl. Microbiol. 65, 366-372. 미소장
9 Bankova, V., Boudourova-Krasteva, G., Sforcin, J. M., Frete, X., Kujumgiev, A. and Maimoni-Rodella, R. 1999. Phytochemical evidence for the plant origin of Brazilian propolis from Sao Paulo state. Z. Naturforsch. C. 54, 401-405. 미소장
10 Bazo, A.P., Rodrigues, M. A. M., Sforcin, J. M., de Camargo, J. L. V., Ribeiro, L. R. and Salvadori, D. M. F. 2002. Protective action of propolis on the rat colon carcinogenesis. Teratog. Carcinog. Mutagen 22, 183-194. 미소장
11 Benguedouar, L., Lahouel, M., Gangloff, S. C., Durlach, A., Grange, F., Bernard, P. and Antonicelli, F. 2015. Algerian ethanolic extract of propolis and galangin decreased melanoma tumour progression in C57BL6 mice. Anticancer Agents Med. Chem. 16, 1172-1183. 미소장
12 Benjamin, E. J., Blaha, M. J., Chiuve, S. E., Cushman, M., Das, S. R., Deo, R., De Ferranti, S. D., Floyd, J., Fornage, M., Gillespie, C., Isasi, C. R., Jimenez, M. C., Jordan, L. C., Judd, S. E., Lackland, D., Lichtman, J. H., Lisabeth, L., Lu, S., Longenecker, C. T., Mackey, R. H., Matsushita, K., Mozaffarian, D., Mussolino, M. E., Nasir, K., Neumar, R. W., Palaniappan, L., Pandey, D. K., Thiagarajan, R. R., Reeves, M. J., Ritchey, M., Rodriguez, C. J., Roth, G. A., Rosamond, W. D., Sasson, C., Towfighi, A., Tsao C. W., Turner, M. B., Virani, S. S., Voeks, J. H., Willey, J. Z., Wilkins, J. T., Wu, J. H., Alger, H. M., Wong, S. S. and... 미소장
13 Bertolini, P. F. R., Biondi Filho, O., Pomilio, A., Pinheiro, S. L. and Carvalho, M. S. D. 2012. Antimicrobial capacity of Aloe vera and propolis dentifrice against Streptococcus mutans strains in toothbrushes: an in vitro study. J. Appl. Oral Sci. 20, 32-37. 미소장
14 Burdock, G. A. 1998. Review of the biological properties and toxicity of bee propolis (propolis). Food Chem. Toxicol. 36, 347-363. 미소장
15 Capoci, I. R. G., Bonfim-Mendonça P. de S., Arita, G. S., Pereira, R. R. de A., Consolaro, M. E. L., Bruschi, M. L., Negri, M. and Svidzinski, T. I. E. 2015. Propolis is an efficient fungicide and inhibitor of biofilm production by vaginal Candida albicans. Evid. Based Complement. Alternat. Med. 2015, 287693. doi: 10.1155/2015/287693. 미소장
16 Chen, T. G., Lee, J. J., Lin, K. H., Shen, C. H., Chou, D. S. and Sheu, J. R. 2007. Antiplatelet activity of caffeic acid phenethyl ester is mediated through a cyclic GMP-dependent pathway in human platelets. Chin. J. Physiol. 50, 121-126. 미소장
17 Cheung, K. W., Sze, D. M., Chan, W. K., Deng, R. X., Tu, W. and Chan, G. C. 2011. Brazilian green propolis and its constituent, artepillin C inhibits allogeneic activated human CD4 T cells expansion and activation. J. Ethnopharmacol. 138, 463-471. 미소장
18 Chikaraishi, Y., Izuta, H., Shimazawa, M., Mishima, S. and Hara, H. 2009. Angiostatic effects of Brazilian green propolis and its chemical constituents. Mol. Nutr. Food Res. 54, 566-575. 미소장
19 Choi, Y. H., Miller, J. M., Tucker, K. L., Hu, H. and Park, S. K. 2014. Antioxidant vitamins and magnesium and the risk of hearing loss in the US general population. Am. J. Clin. Nutr. 99, 148-155. 미소장
20 Cole, N., Sou, P. W., Ngo, A., Tsang, K. H., Severino, J. A. J., Arun, S. J., Duke, C. C. and Reeve, V. E. 2010. Topical ‘Sydney’ propolis protects against UV-radiation-induced inflammation, lipid peroxidation and immune suppression in mouse skin. Int. Arch. Allergy Immunol. 152, 87-97. 미소장
21 Cooke, M. S., Evans, M. D., Dizdaroglu, M. and Lunec, J. 2003. Oxidative DNA damage: mechanisms, mutation, and disease. FASEB J. 17, 1195-1214. 미소장
22 Cunha, I. B. S., Sawaya, A. C. H. F., Caetano, F. M., Shimizu, M. T., Marcucci, M. C., Drezza, F. T., Povia, G. S. and Carvalho, P. O. 2004. Factors that influence the yield and composition of Brazilian propolis extracts. J. Braz. Chem. Soc. 15, 964-970. 미소장
23 Daleprane, J. B., Freitas, V. da S., Pacheco, A., Rudnicki, M., Faine, L. A., Dorr, F. A., Ikegaki, M., Salazar, L. A., Ong, T. P. and Abdalla, D. S. 2012. Antiatherogenic and anti-angiogenic activities of polyphenols from propolis. J. Nutr. Biochem. 23, 557-566. 미소장
24 Dalia, G. and King, R. 2017. Burden of cardiovascular disease (CVD) on economic cost. Comparison of outcomes in US and Europe. Circ. Cardiovasc. Qual. Outcomes 10, A207. 미소장
25 de Freitas, M. C. D., de Mranda, M. B., de Oliveira, D. T., Vieira-Filho, S. A., Caligiorne, R. B. and de Figueiredo, S. M. 2017. Biological activities of red propolis: A review. Recent Pat Endocr Metab Immune. Drug Discov. 11, 3-12. 미소장
26 de Groot, A. C. 2013. Propolis: a review of properties, applications, chemical composition, contact allergy, and other adverse effects. Dermatitis 24, 263-282. 미소장
27 de Lima, R. O., Bazo, A. P., Said R. A., Sforcin, J. M., Bankova, V., Darros, B. R. and Salvadori, D. M. 2005. Modifying effect of propolis on dimethylhydrazine-induced DNA damage but not colonic aberrant crypt foci in rats. Environ. Mol. Mutagen 45, 8-16. 미소장
28 Demestre, M., Messerli, S. M., Celli, N., Shahhossini, M., Kluwe, L., Mautner, V. and Maruta, H. 2009. CAPE (caffeic acid phenethyl ester)-based propolis extract (Bio 30) suppresses the growth of human neurofibromatosis (NF) tumor xenografts in mice. Phytother. Res. 23, 226-230. 미소장
29 Demir, S., Aliyazicioglu, Y., Turan, I., Misir, S., Mentese, A., Yaman, S. O., Akbulut, K., Kilinc, K. and Deger, O. 2016. Antiproliferative and proapoptotic activity of Turkish propolis on human lung cancer cell line. Nutr. Cancer 68, 165-172. 미소장
30 Dimov, V., Ivanovska, N., Manolova, N., Bankova, V., Nikolov, N. and Popov, S. 1991. Immunomodulatory action of propolis. Influence on anti-infections protection and macrophage function. Apidologie 22, 155-162. 미소장
31 Dobrowolski, J. W., Vohora, S. B., Sharma, K., Shah, S. A., Naqvi, S. A. and Dandiya, P. C. 1991. Antibacterial, antifungal, antiamoebic, antiinflammatory and antipyretic studies on propolis bee products. J. Ethnopharmacol. 35, 77-82. 미소장
32 Falcao, S. I., Vale, N., Cos, P., Gomes, P., Freire, C., Maes, L. and Vilas-Boas, M. 2014. In vitro evaluation of Portuguese propolis and floral sources for antiprotozoal, antibacterial and antifungal activity. Phytother. Res. 28, 437-443. 미소장
33 Fang, D., Xiong, Z., Xu, J., Yin, J. and Luo, R. 2019. Chemopreventive mechanisms of galangin against hepatocellular carcinoma: A review. Biomed. Pharmacother. 109, 2054-2061. 미소장
34 Fesen, M. R., Pommier, Y., Leteurtre, F., Hiroguchi, S., Yung, J. and Kohn, K. W. 1994. Inhibition of HIV-1 integrase by flavones, caffeic acid phenethyl ester (CAPE) and related compounds. Biochem. Pharmacol. 48, 595-608. 미소장
35 Fialkow, L., Wang, Y. and Downey, G. P. Reactive oxygen and nitrogen species as signaling molecules regulating neutrophil function. Free Radic. Biol. Med. 42, 153-164. 미소장
36 Freitas, S., Shinohara, L., Sforcin, J. and Guimarães, S. 2006. In vitro effects of propolis on Giardia duodenalis trophozoites. Phytomedicine 13, 170-175. 미소장
37 Fuliang, H. U., Hepburn, H. R., Xuan, H., Chen, M., Daya, S. and Radloff, S. E. 2005. Effects of propolis on blood glucose, blood lipid and free radicals in ratswithdiabetesmellitus. Pharmacol. Res. 51, 147-152. 미소장
38 Fung, K. L., Liang, R. H. and Chan, G. C. 2009. Vincristine but not imatinib could suppress mesenchymal niche's support to lymphoid leukemic cells. Leuk. Lymphoma 51, 515-522. 미소장
39 Ghisalberti, E. L. 1979. Propolis: a review. Bee World 60, 59-84. 미소장
40 Gorinstein, S., Leontowicz, H., Leontowicz, M., Jesion, I., Namiesnik, J., Drzewiecki, J., Park, Y. S., Ham, K. S., Giordani, E. and Trakhtenberg, S. 2011. Influence of two cultivars of persimmon on atherosclerosis indices in rats fed cholesterol-containing diets: Investigation in vitro and in vivo. Nutrition 27, 838-846. 미소장
41 Grassi, D., Aggio, A., Onori, L., Croce, G., Tiberti, S., Ferri, C., Ferri, L. and Desideri, G. 2008. Tea, flavonoids, and nitric oxide-mediated vascular reactivity. J. Nutr. 138, 1554S-1560S. 미소장
42 Hattori, H., Okuda, K., Murase, T., Shigetsura, Y., Narise, K., Semenza, G. L. and Nagasawa, H. 2011. Isolation, identification, and biological evaluation of HIF-1-modulating compounds from Brazilian green propolis. Bioorg. Med. Chem. 19, 5392-5401. 미소장
43 Hosnuter, M., Gurel, A., Babuccu, O., Armutcu, F., Kargi, E. and Isikdemir, A. 2004. The effect of CAPE on lipid peroxidation and nitric oxide levels in the plasma of rats following thermal injury. Burns 30, 121-125. 미소장
44 Iio, A., Ohguchi, K., Maruyama, H., Tazawa, S., Araki, Y., Ichihara, K., Nozawa, Y. and Ito, M. 2012. Ethanolic extracts of Brazilian red propolis increase ABCA1 expression and promote cholesterol efflux from THP-1 macrophages. Phytomedicine 19, 383-388. 미소장
45 Imhof, M., Lipovac, M., Kurz, C., Barta, J., Verhoeven, H. C. and Huber, J. C. 2005. Propolis solution for the treatment of chronic vaginitis. Int. J. Gynaecol. Obstet. 89, 127-132. 미소장
46 Isla, M. I., Moreno, M. I. N., Sampietro, A. R. and Vattuone, M. A. 2001. Antioxidant activity of Argentine propolis extracts. J. Ethnopharmacol. 76, 165-170. 미소장
47 Izuta, H., Shimazawa, M., Tsuruma, K., Araki, Y., Mishima, S. and Hara, H. 2009. Bee products prevent VEGF-induced angiogenesis in human umbilical vein endothelial cells. BMC Complement. Altern. Med. 9, article 45. 미소장
48 Jain, S., Rai, R., Sharma, V. and Batra, M. 2014. Propolis in oral health: a natural remedy. World J. Pharm. Sci. 2, 90-94. 미소장
49 Jang, H., Ahn, H. R., Jo, H., Kim, K. A., Lee, E. H., Lee, K. W., Jung, S. H. and Lee, C. Y. 2014. Chlorogenic acid and coffee prevent hypoxia-induced retinal degeneration. J. Agric. Food Chem. 62, 182-91. 미소장
50 Jeong, I. Y. 2004. Antioxidant activity and radioprotection of two flavonoids from propolis. J. Kor. Soc. Foods Sci. Nutr. 34, 162-166. 미소장
51 Kart, A., Cigremis, Y., Ozen, H. and Dogan, O. 2009. Caffeic acid phenethyl ester prevents ovary ischemia/reperfusion injury in rabbits. Food Chem. Toxicol. 47, 1980-1984. 미소장
52 Kawase, A., Matsumoto, Y., Hadano, M., Ishii, Y. and Iwaki, M. 2009. Differential effects of chrysin on nitrofurantoin pharmacokinetics mediated by intestinal breast cancer resistance protein in rats and mice. J. Pharm. Pharm. Sci. 12, 150-163. 미소장
53 Khayyal, M. T., el-Ghazaly, M. A. and el-Khatib, A. S. 1993. Mechanisms involved in the anti-inflammatory effect of propolis extract. Drugs Exp. Clin. Res. 19, 197-203. 미소장
54 Khlebnikov, A. I., Schepetkin, I. A., Domina, N. G., Kirpotina, L. N. and Quinn, M. T. 2007. Improved quantitative structure-activity relationship models to predict antioxidant activity of flavonoids in chemical, enzymatic, and cellular systems. Bioorg. Med. Chem. 15, 1749-1770. 미소장
55 Khoo, B. Y., Chua, S. L. and Balaram, P. 2010. Apoptotic effects of chrysin in human cancer cell lines. Int. J. Mol. Sci. 11, 2188-2199. 미소장
56 Kim, S. G., Hong, I. P., Woo, S. O., Jang, H. R. and Han, S. M. 2017. UPLC analysis of pinocembrin and antimicrobial activity of propolis collected from different regions in Korea. J. Apiculture 32, 253-259. 미소장
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