본문 바로가기 주메뉴 바로가기
국회도서관 홈으로 정보검색 소장정보 검색

초록보기

Purpose: This study aimed to provide compelling evidence of anti-staphylococcal beta-lactam use for methicillin-susceptible Staphylococcus aureus bloodstream infection (MSSA BSI).

Materials and Methods: We retrospectively collected data on patients with MSSA BSI who were admitted to two academic tertiary-care hospitals from 2010 to 2018. Only patients who received nafcillin, cefazolin, vancomycin, or teicoplanin as definitive therapy were included. The primary outcome was 28-day mortality. To perform unbiased comparisons between both treatments, we used inverse probability of treatment weighting (IPTW) analysis.

Results: A total of 359 patients were divided into two groups based on the definitive therapy used: beta-lactams (n=203), including nafcillin or cefazolin; and glycopeptides (n=156), including vancomycin or teicoplanin. In the IPTW analysis, glycopeptides were associated with significantly increased odds of 28-day mortality (adjusted odds ratio, 3.37; 95% confidence interval, 1.71–6.61; p<0.001). The rate of primary outcome in prespecified subgroups was largely consistent with the main analysis.

Conclusion: Definitive therapy with beta-lactams in patients with MSSA BSI was associated with lower 28-day mortality compared to definitive therapy with glycopeptides.

권호기사

권호기사 목록 테이블로 기사명, 저자명, 페이지, 원문, 기사목차 순으로 되어있습니다.
기사명 저자명 페이지 원문 목차
Effects of asthma medication type on asthma exacerbation in a real-world setting Yong Jun Choi, Chang-Hwa Kim, Jaeuk Lee, Min Kwang Byun, Jae Hwa Cho, Hye Jung Park p. 603-610

Comparison of clinical outcomes for glycopeptides and beta-lactams in methicillin-susceptible Staphylococcus Aureus bloodstream infections Yeon Ju La, Hye Rim Kim, Dong Hyun Oh, Jin Young Ahn, Yong Chan Kim p. 611-618, [1-2]

Canagliflozin ameliorates nonalcoholic fatty liver disease by regulating lipid metabolism and inhibiting inflammation through induction of autophagy Zhipeng Xu, Wenxin Hu, Bin Wang, Ting Xu, Jianning Wang, Dan Wei p. 619-631

Effects of interleukin-17A on the early stages of arterial thrombosis in mice Youngseon Park, Yeseul Shim, Il Kwon, Heow Won Lee, Hyo Suk Nam, Hyun-Jung Choi, Ji Hoe Heo p. 632-639, [1-4]

Application of machine learning approaches to predict postnatal growth failure in very low birth weight infants Jung Ho Han, So Jin Yoon, Hye Sun Lee, Goeun Park, Joohee Lim, Jeong Eun Shin, Ho Seon Eun, Min Soo Park, Soon Min Lee p. 640-647

Ovarian tissue-based hormone replacement therapy recovers menopause Dahyeon Yoo, Nanum Chung, Jungyoung Yoo, Chae Young Song, Chungmo Yang, Hye Won Youm, Kangwon Lee, Jin Hyun Jun, Jaewang Lee, Jung Ryeol Lee p. 648-656

Does the suprascapular nerve move within the suprascapular notch? Biomechanical perspective using the finite element method Yon-Sik Yoo, Seong-wook Jang, Yoon Sang Kim, Jung-Ah Choi, Jung Hyun Oh, Jeung Yeol Jeong p. 657-664

What affects segmental lordosis of the surgical site after minimally invasive transforaminal lumbar interbody fusion? Soo-Heon Kim, Bang Sang Hahn, Jeong-Yoon Park p. 665-674

Initial abdominal CT and laboratory findings prior to diagnosis of Crohn's disease in children Choeum Kang, Haesung Yoon, Sowon Park, Jisoo Kim, Kyunghwa Han, Seung Kim, Hong Koh, Mi-Jung Lee, Hyun Joo Shin p. 675-682

Re-assessment of applicability of greulich and pyle-based bone age to Korean children using manual and deep learning-based automated method Jisun Hwang, Hee Mang Yoon, Jae-Yeon Hwang, Pyeong Hwa Kim, Boram Bak, Byeong Uk Bae, Jinkyeong Sung, Hwa Jung Kim, Ah Young Jung, Young Ah Cho, Jin Seong Lee p. 683-691, [1-5]

Machine learning model for classifying the results of fetal cardiotocography conducted in high-risk pregnancies Tae Jun Park, Hye Jin Chang, Byung Jin Choi, Jung Ah Jung, Seongwoo Kang, Seokyoung Yoon, Miran Kim, Dukyong Yoon p. 692-700, [1-6]

Short-term outcomes of the first in vivo gene therapy for RPE65-mediated retinitis pigmentosa Jay Jiyong Kwak, Hae Rang Kim, Suk Ho Byeon p. 701-705

참고문헌 (36건) : 자료제공( 네이버학술정보 )

참고문헌 목록에 대한 테이블로 번호, 참고문헌, 국회도서관 소장유무로 구성되어 있습니다.
번호 참고문헌 국회도서관 소장유무
1 Kern WV, Rieg S. Burden of bacterial bloodstream infection-a brief update on epidemiology and significance of multidrug-resistant pathogens. Clin Microbiol Infect 2020;26:151-7. 미소장
2 Gagliotti C, Högberg LD, Billström H, Eckmanns T, Giske CG, Heuer OE, et al. Staphylococcus aureus bloodstream infections:diverging trends of meticillin-resistant and meticillin-susceptible isolates, EU/EEA, 2005 to 2018. Euro Surveill 2021;26:2002094. 미소장
3 van Hal SJ, Jensen SO, Vaska VL, Espedido BA, Paterson DL, Gosbell IB. Predictors of mortality in Staphylococcus aureus bacteremia. Clin Microbiol Rev 2012;25:362-86. 미소장
4 Lam JC, Gregson DB, Robinson S, Somayaji R, Conly JM, Parkins MD. Epidemiology and outcome determinants of Staphylococcus aureus bacteremia revisited: a population-based study. Infection 2019;47:961-71. 미소장
5 Liu C, Bayer A, Cosgrove SE, Daum RS, Fridkin SK, Gorwitz RJ, et al. Clinical practice guidelines by the infectious diseases society of america for the treatment of methicillin-resistant Staphylococcus aureus infections in adults and children. Clin Infect Dis 2011;52:e18-55. 미소장
6 Kim NH, Koo HL, Choe PG, Cheon S, Kim M, Lee MJ, et al. Inappropriate continued empirical vancomycin use in a hospital with a high prevalence of methicillin-resistant Staphylococcus aureus. Antimicrob Agents Chemother 2015;59:811-7. 미소장
7 Centers for Disease Control and Prevention (CDC). Staphylococcus aureus resistant to vancomycin--United States, 2002. MMWR Morb Mortal Wkly Rep 2002;51:565-7. 미소장
8 Lodise TP, Lomaestro B, Graves J, Drusano GL. Larger vancomycin doses (at least four grams per day) are associated with an increased incidence of nephrotoxicity. Antimicrob Agents Chemother 2008;52:1330-6. 미소장
9 Stryjewski ME, Szczech LA, Benjamin DK Jr, Inrig JK, Kanafani ZA, Engemann JJ, et al. Use of vancomycin or first-generation cephalosporins for the treatment of hemodialysis-dependent patients with methicillin-susceptible Staphylococcus aureus bacteremia. Clin Infect Dis 2007;44:190-6. 미소장
10 Kim SH, Kim KH, Kim HB, Kim NJ, Kim EC, Oh MD, et al. Outcome of vancomycin treatment in patients with methicillin-susceptible Staphylococcus aureus bacteremia. Antimicrob Agents Chemother 2008;52:192-7. 미소장
11 Schweizer ML, Furuno JP, Harris AD, Johnson JK, Shardell MD, McGregor JC, et al. Comparative effectiveness of nafcillin or cefazolin versus vancomycin in methicillin-susceptible Staphylococcus aureus bacteremia. BMC Infect Dis 2011;11:279. 미소장
12 Horan TC, Andrus M, Dudeck MA. CDC/NHSN surveillance definition of health care-associated infection and criteria for specific types of infections in the acute care setting. Am J Infect Control 2008;36:309-32. 미소장
13 Paterson DL, Ko WC, Von Gottberg A, Mohapatra S, Casellas JM, Goossens H, et al. Antibiotic therapy for Klebsiella pneumoniae bacteremia: implications of production of extended-spectrum beta-lactamases. Clin Infect Dis 2004;39:31-7. 미소장
14 Hilf M, Yu VL, Sharp J, ZuravleffJJ, Korvick JA, Muder RR. Antibiotic therapy for Pseudomonas aeruginosa bacteremia: outcome correlations in a prospective study of 200 patients. Am J Med 1989;87:540-6. 미소장
15 Vallés J, León C, Alvarez-Lerma F. Nosocomial bacteremia in critically ill patients: a multicenter study evaluating epidemiology and prognosis. Spanish Collaborative Group for Infections in Intensive Care Units of Sociedad Espanola de Medicina Intensiva y Unidades Coronarias (SEMIUC). Clin Infect Dis 1997;24:387-95. 미소장
16 Fowler VG Jr, Sakoulas G, McIntyre LM, Meka VG, Arbeit RD, Cabell CH, et al. Persistent bacteremia due to methicillin-resistant Staphylococcus aureus infection is associated with agr dysfunction and low-level in vitro resistance to thrombin-induced platelet microbicidal protein. J Infect Dis 2004;190:1140-9. 미소장
17 Bosso JA, Nappi J, Rudisill C, Wellein M, Bookstaver PB, Swindler J, et al. Relationship between vancomycin trough concentrations and nephrotoxicity: a prospective multicenter trial. Antimicrob Agents Chemother 2011;55:5475-9. 미소장
18 Youngster I, Shenoy ES, Hooper DC, Nelson SB. Comparative evaluation of the tolerability of cefazolin and nafcillin for treatment of methicillin-susceptible Staphylococcus aureus infections in the outpatient setting. Clin Infect Dis 2014;59:369-75. 미소장
19 Yaw LK, Robinson JO, Ho KM. A comparison of long-term outcomes after meticillin-resistant and meticillin-sensitive Staphylococcus aureus bacteraemia: an observational cohort study. Lancet Infect Dis 2014;14:967-75. 미소장
20 Braquet P, Alla F, Cornu C, Goehringer F, Piroth L, Chirouze C, et al. Factors associated with 12 week case-fatality in Staphylococcus aureus bacteraemia: a prospective cohort study. Clin Microbiol Infect 2016;22:948.e1-7. 미소장
21 Nambiar K, Seifert H, Rieg S, Kern WV, Scarborough M, Gordon NC, et al. Survival following Staphylococcus aureus bloodstream infection: a prospective multinational cohort study assessing the impact of place of care. J Infect 2018;77:516-25. 미소장
22 Austin PC, Stuart EA. Moving towards best practice when using inverse probability of treatment weighting (IPTW) using the propensity score to estimate causal treatment effects in observational studies. Stat Med 2015;34:3661-79. 미소장
23 Chang FY, Peacock JE Jr, Musher DM, Triplett P, MacDonald BB, Mylotte JM, et al. Staphylococcus aureus bacteremia: recurrence and the impact of antibiotic treatment in a prospective multicenter study. Medicine (Baltimore) 2003;82:333-9. 미소장
24 Turnidge JD, Kotsanas D, Munckhof W, Roberts S, Bennett CM, Nimmo GR, et al. Staphylococcus aureus bacteraemia: a major cause of mortality in Australia and New Zealand. Med J Aust 2009;191:368-73. 미소장
25 Ruth C, Brownell M, Isbister J, MacWilliam L, Gammon H, Singal D, et al. Long-term outcomes of Manitoba’s insight mentoring program:a comparative statistical analysis. Winnipeg: Manitoba Centre for Health Policy; 2015. 미소장
26 Kourtis AP, Hatfield K, Baggs J, Mu Y, See I, Epson E, et al. Vital signs: epidemiology and recent trends in methicillin-resistant and in methicillin-susceptible Staphylococcus aureus bloodstream infections—United States. MMWR Morb Mortal Wkly Rep 2019;68:214-9. 미소장
27 Choi SH, Lee J, Jung J, Kim ES, Kim MJ, Chong YP, et al. A longitudinal study of adult patients with Staphylococcus aureus bacteremia over 11 years in Korea. J Korean Med Sci 2021;36:e104. 미소장
28 Kim CJ, Kim HB, Oh MD, Kim Y, Kim A, Oh SH, et al. The burden of nosocomial staphylococcus aureus bloodstream infection in South Korea: a prospective hospital-based nationwide study. BMC Infect Dis 2014;14:590. 미소장
29 Lee H, Yoon EJ, Kim D, Jeong SH, Won EJ, Shin JH, et al. Antimicrobial resistance of major clinical pathogens in South Korea, May 2016 to April 2017: first one-year report from Kor-GLASS. Euro Surveill 2018;23:1800047. 미소장
30 Wong D, Wong T, Romney M, Leung V. Comparative effectiveness of β-lactam versus vancomycin empiric therapy in patients with methicillin-susceptible Staphylococcus aureus (MSSA) bacteremia. Ann Clin Microbiol Antimicrob 2016;15:27. 미소장
31 Park GE, Ko JH, Cho SY, Ha YE, Lee NY, Kang CI, et al. Empirical combination of a β-lactam to vancomycin may not improve outcomes of methicillin-susceptible Staphylococcus aureus bacteremia, compared to vancomycin monotherapy. Eur J Clin Microbiol Infect Dis 2017;36:1091-6. 미소장
32 Cantoni L, Glauser MP, Bille J. Comparative efficacy of daptomycin, vancomycin, and cloxacillin for the treatment of Staphylococcus aureus endocarditis in rats and role of test conditions in this determination. Antimicrob Agents Chemother 1990;34:2348-53. 미소장
33 Dahlgren AF. Adverse drug reactions in home care patients receiving nafcillin or oxacillin. Am J Health Syst Pharm 1997;54:1176-9. 미소장
34 Henson KE, Levine MT, Wong EA, Levine DP. Glycopeptide antibiotics:evolving resistance, pharmacology and adverse event profile. Expert Rev Anti Infect Ther 2015;13:1265-78. 미소장
35 LaPlante KL, Rybak MJ. Impact of high-inoculum Staphylococcus aureus on the activities of nafcillin, vancomycin, linezolid, and daptomycin, alone and in combination with gentamicin, in an in vitro pharmacodynamic model. Antimicrob Agents Chemother 2004;48:4665-72. 미소장
36 Rybak MJ. The pharmacokinetic and pharmacodynamic properties of vancomycin. Clin Infect Dis 2006;42 Suppl 1:S35-9. 미소장