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Restless leg syndrome is a nervous system disorder that causes an overpowering urge to move one’s legs. Symptoms of restless leg syndrome usually worsen when one tries to fall asleep and can prevent sufficient sleep. Restless leg syndrome is common in patients with chronic kidney failure and can be caused or worsened by chronic kidney failure and hemodialysis. Various medications can treat restless leg syndrome, though the long-term use of medications can cause augmentation and adverse effects. In addition, the use of dopamine agonists is limited in patients with chronic kidney failure. This is because the dose of administration should be controlled for patients with chronic kidney failure, and the treatment effect has not been clearly proven. This study reports the case of a 56-year-old male diagnosed with chronic kidney failure complaining of uncomfortable leg sensations. The patient underwent Korean medicine treatment using Jakyakgamcho-tang. The IRLS, NRS, and AIS scores were evaluation tools during treatment. This study suggested significantly improved symptoms through the individual interventions of Jakyakgamcho-tang in a restless leg syndrome patient with chronic kidney failure.
번호 | 참고문헌 | 국회도서관 소장유무 |
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1 | Choi HS, Kang SG, Boo CS, Lee HJ, Cho WY, Kim HK, et al. Restless Legs Syndrome and Quality of Life in Hemodialysis Patients. Sleep Medicine and Psychophysiology 2007;14(2):99-106. | 미소장 |
2 | Min YS. Diagnosis and Treatment of Restless Legs Syndrome. Brain & NeuroRehabilitation 2016;9(1):25-30. | 미소장 |
3 | Cho YW, Suh YS. Restless Legs Syndrome: An Update in Diagnosis and Management. Korean Journal of Family Medicine 2008;29(4):241-50. | 미소장 |
4 | Kim SW, Jang JE, Kim SY, Kim JM, Shin IS, Yang SJ, et al. Pharmacologic Treatment of Restless Legs Syndrome. The Korean Journal of Psychopharmacology 2010;21(1):14-21. | 미소장 |
5 | Seo Y, Jin C, Jang BH, Jeon JP, Lee YS, Yang SB, et al. Successful treatment of restless leg syndrome with the traditional herbal medicines Dangguijakyak-san and Shihogyeji-tang: A case report (CARE-compliant). Medicine(Baltimore)2021;100(31):e26800. | 미소장 |
6 | Park SM, Kang BG, Han DJ, Lee JW, Na RH, Bang CH, et al. Clinical Case Report of Restless Leg Syndrome in Ischemic Stroke Patients. Korean J Oriental Physiology & Pathology 2008;22(4):975-81. | 미소장 |
7 | Yoo HJ, Kyung HS, Kong KH. A Clinical Case Report of Insomnia in Restless Legs Syndrome. The Journal of Internal Korean Medicine 2006;fal:132-8. | 미소장 |
8 | Kim SJ, Jung SY, Hong JS, Choi JU, Lee CR, Choo WJ, et al. A Clinical Case Report of Restless Leg Syndrome in Herniation of Lumbar Intervertebral Disc (HIVD). The Journal of Internal Korean Medicine 2014;spr:217-26. | 미소장 |
9 | Yang JY, Kim SW, Lee YJ, Cho KH, Moon SK, Jung WS, et al. A Case of Restless Legs Syndrome Patient with Numbness in Both Soles Using Gyejibokryeong-hwan. The Journal of Internal Korean Medicine 2019;40(2):270-8. | 미소장 |
10 | Kim GM, Suh WJ, Kim SB, Cho KH, Moon SK, Jung WS, et al. A Case Report on Heat Sensation in Both Feet Caused by Restless Leg Syndrome Using Conservative Korean Medical Treatment. The Journal of Internal Korean Medicine 2018;39(2):116-29. | 미소장 |
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12 | Rheu KH, Kim DH, Bae EJ, Park SU, Yoon SW, Ko CN. A Case Report of Improvement of Glomerular Filtration Rate and Anemia in Chronic Renal Failure through Herbal Medication. The Journal of Internal Korean Medicine 2005;26(2):498-505. | 미소장 |
13 | Kim JM, Kwon SW. Two case reports of Renal failure induced by IgA nephropathy patients treated by Astragalus membranaceus. The Journal of Internal Korean Medicine 2014;fal:381-6. | 미소장 |
14 | Kang SG. Updates on the Diagnosis and Treatment of Restless Legs Syndrome. Korean Neuropsychiatric Association 2020;59(1):13-9. | 미소장 |
15 | Choi HS, Kang SG, Boo CS, Lee HJ, Cho WY, Kim HK, et al. Restless Legs Syndrome and Quality of Life in Hemodialysis Patients. Sleep Medicine and Psychophysiology 2007;14(2):99-106. | 미소장 |
16 | Allen RP. Minimal clinically significant change for the International Restless Legs Syndrome Study Group rating scale in clinical trials is a score of 3. Sleep medicine 2013;14(11):1229. | 미소장 |
17 | Okajima I, Miyamoto T, Ubara A, Omichi C, Matsuda A, Sumi Y, et al. Evaluation of Severity Levels of the Athens Insomnia Scale Based on the Criterion of Insomnia Severity Index. International Journal of Environmental Research and Public Health 2020;17(23):8789. | 미소장 |
18 | Jung KY. Diagnosis and Treatment of Restless Legs Syndrome. Hanyang Medical Reviews 2013;33(4):216-20. | 미소장 |
19 | Lin Z, Zhao C, Luo Q, Xia X, Yu X, Huang F. Prevalence of restless legs syndrome in chronic kidney disease: a systematic review and metaanalysis of observational studies. Renal Failure 2016;38(9):1335-46. | 미소장 |
20 | Kwon SW, Jin C, Cho SY, Park SU, Jung WS, Moon SK, et al. Paeoniae Radix-containing herbal medicine for patients with restless legs syndrome: A systematic review and meta-analysis. Complementary Therapies Clinical Practices 2019;35:329-41. | 미소장 |
21 | Sung YY, Yuk HJ, Kim DS. Comparison of Ingredient Quantities and Anti-Fatigue Effects of Jakyakgamcho-Tang according to Extraction Solvent. Korean journal of herbology 2020;35(2):31-8. | 미소장 |
22 | Lee KK, Omiya Y, Yuzurihara M, Kase Y, Kobayashi H. Antispasmodic effect of shakuyakukanzoto extract on experimental muscle cramps in vivo:role of the active constituents of Glycyrrhizae radix. J Ethnopharmacol 2013;145(1):286-93. | 미소장 |
23 | Suganami A, Sakamoto K, Ono T, Watanabe H, Hijioka N, Murakawa M, et al. The inhibitory effect of shakuyakukanzoto on K+ current in H9c2 cells. Fukushima J Med Sci 2014;60(1):22-30. | 미소장 |
24 | Hyodo T, Taira T, Kumakura M, Yamamoto S, Yoshida K, Uchida T, et al. The immediate effect of Shakuyakukanzo-to, traditional Japanese herbal medicine, for muscular cramps during maintenance hemodialysis. Nephron 2002;90(2):240. | 미소장 |
25 | Hinoshita F, Ogura Y, Suzuki Y, Hara S, Yamada A, Tanaka N, et al. Effect of orally administered shao-yao-gan-cao-tang (Shakuyakukanzo-to) on muscle cramps in maintenance hemodialysis patients: a preliminary study. Am J Chin Med 2003;31(3):445-53. | 미소장 |
26 | Hyodo T, Taira T, Takemura T, Yamamoto S, Tsuchida M, Yoshida K, et al. Immediate effect of Shakuyaku-kanzo-to on muscle cramp in hemodialysis patients. Nephron Clin Pract 2006;104(1):28-32. | 미소장 |
27 | Ferrari P. Licorice: a sweet alternative to prevent hyperkalemia in dialysis patients?. Kidney International 2009;76(8):811-2. | 미소장 |
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