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22대 대한민국 국회 국회정보길라잡이 국회의원검색
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Purpose: There is limited information on the clinical characteristics and prognosis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection during pregnancy. The clinical features and risk factors for hypoxemia development were investigated in pregnant women with coronavirus disease-2019 (COVID-19).

Materials and Methods: From August 2020 to February 2022, we performed a retrospective cohort study of 410 pregnant women with COVID-19. The clinical characteristics and prognoses were compared between pregnant COVID-19 patients requiring oxygen and those who did not.

Results: Of 410 patients, 100 (24.4%) required oxygen therapy. Among them, fever [163 (52.6%) vs. 81 (81.0%), p〈0.001] and cough [172 (56.4%) vs. 73 (73.0%), p=0.003] were more frequently observed than in non-oxygen group. The proportion of unvaccinated women was higher in oxygen group than in non-oxygen group [264 (85.2%) vs. 98 (98.0%), p=0.003]. During the Omicron wave, patients were more likely to have no oxygen requirement [98 (31.6%) vs. 18 (18.0%), p=0.009]. The risk of hypoxemic respiratory difficulty increased if SARS-CoV-2 infection occurred during the third trimester [adjusted odds ratio (aOR) 5.083, 95% confidence interval (CI): 1.095–23.593, p=0.038] and C-reactive protein (CRP) was elevated (≥1.0 mg/dL) at admission (aOR 5.878, 95% CI: 3.099–11.146, p〈0.001). The risk was higher in unvaccinated patients (aOR 5.376, 95% CI: 1.193-24.390, p=0.028). However, the risk was lower in patients during the Omicron wave (aOR 0.498, 95% CI: 0.258–0.961, p=0.038).

Conclusion: A quarter of SARS-CoV-2-infected women developed hypoxemic respiratory difficulty during pregnancy. SARSCoV-2 infection during the third trimester, CRP elevation at admission, and no vaccination increased the risk of hypoxemia in pregnant women.

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참고문헌 (40건) : 자료제공( 네이버학술정보 )

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번호 참고문헌 국회도서관 소장유무
1 Causes and Mechanisms of Intrauterine Hypoxia and Its Impact on the Fetal Cardiovascular System: A Review 미소장
2 The influence of pregnancy on systemic immunity 미소장
3 Pregnancy and perinatal outcomes of women with severe acute respiratory syndrome 미소장
4 Maternal fever and birth outcome: A prospective study 미소장
5 Presentation of Seasonal Influenza A in Pregnancy 미소장
6 2009 pandemic influenza A (H1N1) in pregnancy: a systematic review of the literature 미소장
7 Pregnancy and Infection 미소장
8 Pregnancy and pregnancy-associated hormones alter immune responses and disease pathogenesis 미소장
9 Pandemic 2009 Influenza A(H1N1) Virus Illness Among Pregnant Women in the United States 미소장
10 Infants Born to Mothers With Severe Acute Respiratory Syndrome 미소장
11 Pregnancy-Related Mortality Resulting From Influenza in the United States During the 2009–2010 Pandemic 미소장
12 Coronavirus Disease 2019 (COVID-19) and pregnancy: what obstetricians need to know 미소장
13 Pregnancy and Perinatal Outcomes of Women With Coronavirus Disease (COVID-19) Pneumonia: A Preliminary Analysis 미소장
14 Outcome of coronavirus spectrum infections (SARS, MERS, COVID-19) during pregnancy: a systematic review and meta-analysis 미소장
15 Maternal death due to COVID-19 미소장
16 A minimal common outcome measure set for COVID-19 clinical research 미소장
17 Pathophysiology, Transmission, Diagnosis, and Treatment of Coronavirus Disease 2019 (COVID-19) 미소장
18 Are clinical outcomes worse for pregnant women at ≥20 weeks’ gestation infected with coronavirus disease 2019? A multicenter case-control study with propensity score matching 미소장
19 Clinical manifestations, risk factors, and maternal and perinatal outcomes of coronavirus disease 2019 in pregnancy: living systematic review and meta-analysis 미소장
20 Update: Characteristics of Symptomatic Women of Reproductive Age with Laboratory-Confirmed SARS-CoV-2 Infection by Pregnancy Status — United States, January 22–October 3, 2020 미소장
21 Disease severity, pregnancy outcomes, and maternal deaths among pregnant patients with severe acute respiratory syndrome coronavirus 2 infection in Washington State 미소장
22 Risk factors for severe and critical Covid-19 in pregnant women in a single center in Brazil 미소장
23 Disease Severity and Perinatal Outcomes of Pregnant Patients With Coronavirus Disease 2019 (COVID-19) 미소장
24 Pregnancy and neonatal outcomes of COVID‐19: coreporting of common outcomes from PAN‐COVID and AAP‐SONPM registries 미소장
25 Risk Factors for Illness Severity Among Pregnant Women With Confirmed Severe Acute Respiratory Syndrome Coronavirus 2 Infection—Surveillance for Emerging Threats to Mothers and Babies Network, 22 State, Local, and Territorial Health Departments, 29 March 2020–5 March 2021 미소장
26 Effects of the COVID-19 pandemic on maternal and perinatal outcomes: a systematic review and meta-analysis 미소장
27 Maternal and Neonatal Morbidity and Mortality Among Pregnant Women With and Without COVID-19 Infection 미소장
28 The incidence, characteristics and outcomes of pregnant women hospitalized with symptomatic and asymptomatic SARS-CoV-2 infection in the UK from March to September 2020: A national cohort study using the UK Obstetric Surveillance System (UKOSS) 미소장
29 In-Hospital Mortality in a Cohort of Hospitalized Pregnant and Nonpregnant Patients With COVID-19 미소장
30 Severe Acute Respiratory Syndrome Coronavirus 2 and Pregnancy Outcomes According to Gestational Age at Time of Infection 미소장
31 Pregnancy and birth outcomes after SARS-CoV-2 vaccination in pregnancy 미소장
32 Maternal Outcomes After Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Vaccinated Compared With Unvaccinated Pregnant Patients. 미소장
33 Characteristics and Outcomes of Hospitalized Patients in South Africa During the COVID-19 Omicron Wave Compared With Previous Waves 미소장
34 Oxygen saturation in pregnant individuals with COVID-19: time for re-appraisal? 미소장
35 Systematic review and meta-analysis of COVID-19 maternal and neonatal clinical features and pregnancy outcomes up to June 3, 2021 미소장
36 Association of SARS-CoV-2 Infection During Pregnancy With Maternal and Perinatal Outcomes 미소장
37 Maternal Outcomes After Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection in Vaccinated Compared With Unvaccinated Pregnant Patients 미소장
38 SARS-CoV-2 variants and pregnant Women: A cause for Concern? 미소장
39 Clinical Characteristics of Patients Who Contracted the SARS-CoV-2 Omicron Variant from an Outbreak in a Single Hospital 미소장
40 Maternal and Neonatal Outcomes in Pregnant Women With Coronavirus Disease 2019 in Korea 미소장

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