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국회도서관 홈으로 정보검색 소장정보 검색

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Macular degeneration is a disease in which the macula, the central part of the retina, is damaged and is one of the three major eye diseases along with glaucoma and diabetic retinopathy. Most of the optic cells and optic nerves are located here, and it is the most important place for vision as it is where images of objects are formed. The main symptom of macular degeneration is the inability to clearly distinguish the shape of objects or the ability to distinguish colors and light and dark. It is also a serious eye disease that causes black spots in the center of the field of vision. However, because it is difficult to distinguish from the form of vision loss caused by presbyopia, early diagnosis is often missed. The most commonly used treatment for macular degeneration is antibody injection therapy. This treatment requires regular injections once every 1 to 2 months. During antibody injection treatment, the fear of having to inject directly into the eye and the cost of repeated procedures over a long period of time are a great burden to patients. To overcome these problems, sustained-release preparations are being developed in special dosage forms using drug delivery systems. The drug release rate and release time can be adjusted, dramatically reducing the number of drug administrations. However, micro-implants (∅0.46x6.0mm), which are sustained-release preparations, are highly brittle because biodegradable resin (PLGA) and therapeutic agent are mixed in a 4:6 ratio. Therefore, there is a high risk of it being damaged during handling. When physical force is applied to the micro-implant to cut it to a certain size, the cutting surface is rough and the length is not accurate. Therefore, in this study, laser cutting equipment was used to cut the micro-implant. In addition, the cutting surface properties according to the laser type were analyzed, and in particular, the content of flexible substances (Dexamethasone Acid, Dexamethasone Ketone, Dexamethasone Aldehyde) according to heat exposure was analyzed.

권호기사

권호기사 목록 테이블로 기사명, 저자명, 페이지, 원문, 기사목차 순으로 되어있습니다.
기사명 저자명 페이지 원문 목차
금형의 절삭가공에서 표면거칠기 예측 수식의 유사-실험 데이터 활용을 위한 인공신경망 구축에 대한 연구 = A study on the establishment of artificial neural networks for the use of similar-experimental transition data of surface roughness prediction equation in mold machining 김지우, 이준한, 이동원, 김종선, 김종수 p. 1-10

3D 프린팅된 인장 시편의 인장강도 향상을 위한 머신러닝 = Machine learning to improve tensile strength of 3D-printed tensile specimens 김범수, 한성열 p. 11-17

자중을 이용한 곡면유리의 열 성형 공정에서 금형의 형상이 미치는 영향에 관한 연구 = A study on the effect of mold shape in thermal molding process of curved glass using self-weight 이광호, 이동원, 김순욱, 김종수 p. 18-25

적층제조시편 성능 평가를 위한 전산해석 모델링 도출에 관한 연구 = A study on computational analysis modeling for evaluating the performance of additive manufacturing specimen 송여울, 이필호, 신동운, 백경윤 p. 26-31

가상 생산 기술 개발을 위한 자동차 부품 정확성 검증 연구 = Accuracy verification research of automobile parts for virtual production technology development 김민준, 김석중, 이춘규 p. 32-38

게이트 종류에 따른 라디에이터 그릴의 해석결과와 비교에 대한 연구 = A study on analysis results and comparison of radiator grille by gate type 유영태, 이춘규 p. 39-45

게이트와 Glass Fiber 함유량이 사출품의 변형에 미치는 영향에 대한 연구 = A study on the effect of gate and glass fiber content on deformation of injection molded products 문성민, 전성영, 김성교, 윤재웅 p. 46-52

대형 Flange bolt의 냉간단조 성형공법 적용에 관한 연구 = A study of the application of cold forging technique for a big flange bolton coupling 이권수, 안용식 p. 53-60

가속도 센서를 사용한 마그네슘 합금 판재의 변형 및 파손 분석 = Deformation and fracture analysis of magnesium alloy sheets using acceleration sensor 이서준, 김지선, 정완진, 이창환 p. 61-70

레이저 커팅에 의한 황반변성 치료제의 절단면 성상 및 유연물질 분석 = Analysis of cutting surface description and impurities for macular degeneration medicine by laser cutting 이정원, 김용대, 최용준 p. 71-78