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Background: Philadelphus schrenkii Rupr. is a widespread in East Asia and has historically been used as a medicinal herb in Korea to reduce heat, swelling, and pain. This study investigated the anti-inflammatory effects of P. schrenkii methanol extract (PSE) on lipopolysaccharide-stimulated RAW 264.7 macrophage cells.

Methods and Results: PSE inhibited the expression of nitric oxide, prostaglandin E2, inducible nitric oxide synthase, and cyclooxygenase-2 at concentrations that did not affect cell viability as determined by the tetrazolium salt (WST-1) assay. The quantitative reverse transcription polymerase chain reaction and enzyme-linked immunosorbent assay measured that pro-inflammatory cytokines, including tumor necrosis factor-α, interleukin (IL)-1β, IL-6, and monocyte chemoattracted protein-1, were decreased in PSE-treated groups. Western blotting confirmed that PSE inhibited the phosphorylation of nuclear factor kappa B and mitogen-activated protein kinases. Gas chromatography-mass spectrometry analysis revealed the presence of active anti-inflammatory compounds in PSE.

Conclusions: This study demonstrated that PSE has potent anti-inflammatory activity in vitro and provides a reasonable basis for the traditional use of P. schrenkii in treating inflammation-related diseases.

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기사명 저자명 페이지 원문 목차
Anti-inflammatory activity of Philadelphus schrenkii methanol extract in lipopolysaccharide-stimulated RAW 264.7 cells = LPS로 자극된 RAW 264.7 대식세포에서의 고광나무 메탄올 추출물의 항염증 활성 So Hee Bae, Min Jae Kang, Ik Jung Kwon, Sang Hyun Son, Gun Do Kim p. 121-135

한국 및 중국 재래종 생강의 형태학적 특성 및 진저롤 함량 비교 = Comparative analysis of morphological characteristics and gingerol components of ginger landraces from Korea and China 유진, 구성철, 장인복, 김동휘, 김수진 p. 136-143

꾸지뽕나무 잎 추출물의 1,1-Diphenyl-2-picrylhydrazyl Radical 소거 활성 성분 분석 = 1,1-diphenyl-2-picrylhydrazyl radical scavenging active compound analysis in extracts of Cudrania tricuspidata leaves 이경인, 윤영승, 최철희 p. 144-151

광주기 조절을 통한 단삼의 생장, 외적품질, 생리적 특성 개선 = Improvement in growth, external quality, and physiological characteristics of Salvia miltiorrhiza bunge through photoperiod control 김은아, 이재환, 선우영, 신은지, 남상용 p. 152-162

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번호 참고문헌 국회도서관 소장유무
1 Al-Marzoqi AH, Hadi MY and Hameed IH. (2016). Determination of metabolites products by Cassia angustifolia and evaluate antimicrobial activity. Journal of Pharmacognosy and Phytotherapy. 8:25-48. 미소장
2 Alonso-Castro AJ, Serrano-Vega R, Perez Gutierrez S, Isiordia- Espinoza MA and Solorio-Alvarado CR. (2022). Myristic acid reduces skin inflammation and nociception. Journal of Food Biochemistry. 46:e14013. https://onlinelibrary.wiley.com/ doi/full/10.1111/jfbc.14013 (cited by 2024 February 27). 미소장
3 Ameamsri U, Chaveerach A, Sudmoon R, Tanee T, Peigneur S and Tytgat J. (2021). Oleamide in Ipomoea and Dillenia species and inflammatory activity investigated through ion channel inhibition. Current Pharmaceutical Biotechnology. 22:254-261. 미소장
4 Aparna V, Dileep KV, Mandal PK, Karthe P, Sadasivan C and Haridas M. (2012). Anti-inflammatory property of n- hexadecanoic acid: Structural evidence and kinetic assessment. Chemical Biology and Drug Design. 80:434-439. 미소장
5 Asanka Sanjeewa K, Fernando I, Kim SY, Kim WS, Ahn Gn, Jee Yh and Jeon YJ. (2019). Ecklonia cava(Laminariales) and Sargassum horneri(Fucales) synergistically inhibit the lipopoly- saccharide-induced inflammation via blocking NF-κB and MAPK pathways. Algae. 34:45-56. 미소장
6 Ben Neriah Y and Karin M. (2011). Inflammation meets cancer, with NF-κB as the matchmaker. Nature Immunology. 12:715-723. 미소장
7 Cao J, Li Q, Shen X, Yao Y, Li L and Ma H. (2021). Dehydroepiandrosterone attenuates LPS-induced inflammatory responses via activation of Nrf2 in RAW264.7 macrophages. Molecular Immunology. 131:97-111. 미소장
8 Chakrabarti M and Mukherjee A. (2021). Investigating the underlying mechanism of cadmium-induced plant adaptive response to genotoxic stress. Ecotoxicology and Environmental Safety. 209:111817. https://www.sciencedirect.com/science/article/pii/S01476 51320316535 (cited by 2024 March 31). 미소장
9 Chang MC, Chang HH, Wang TM, Chan CP, Lin BR, Yeung SY, Yeh CY, Cheng RH and Jeng JH. (2014). Antiplatelet effect of catechol is related to inhibition of cyclooxygenase, reactive oxygen species, ERK/p38 signaling and thromboxane A2 production. PLOS ONE. 9:e104310. https://journals.plos.org/ plosone/article?id=10.1371/journal.pone.0104310 (cited by 2024 February 27). 미소장
10 Chen L, Deng H, Cui H, Fang J, Zuo Z, Deng J, Li Y, Wang X and Zhao L. (2018). Inflammatory responses and inflammation- associated diseases in organs. Oncotarget. 9:7204-7218. 미소장
11 Chinnadurai V, Viswanathan P, Kalimuthu K, Vanitha A, Ranjitha V and Pugazhendhi A. (2019). Comparative studies of phytochemical analysis and pharmacological activities of wild and micropropagated plant ethanol extracts of Manihot esculenta. Biocatalysis and Agricultural Biotechnology. 19:101166. https://www.sciencedirect.com/science/article/abs/pii/ S1878818119304517 (cited by 2024 February 27). 미소장
12 Chippada SC, Volluri SS, Bammidi SR and Vangalapati M. (2011). In vitro Anti-inflammatory activity of methanolic extract of centella asiatica by HRBC membrane stabilisation. Rasayan Journal of Chemistry. 4:457-460. 미소장
13 Chuang LT, Shih YH, Huang WC, Lin LC, Hsu C, Chyuan JH, Tsai TH and Tsai PJ. (2020). In vitro and in vivo screening of wild bitter melon leaf for anti-inflammatory activity against Cutibacterium acnes. Molecules. 25:4277. https:// www.mdpi.com/1420-3049/25/18/4277 (cited by 2024 February 27). 미소장
14 Closse A, Haefliger W, Hauser D, Gubler HU, Dewald B and Baggiolini M. (1981). 2, 3-Dihydrobenzofuran-2-ones: A new class of highly potent anti-inflammatory agents. Journal of Medicinal Chemistry. 24:1465-1471. 미소장
15 da Silva RM, Moreira DKT, Zarricueta ML, Macedo JA, Macedo GA and Gambero A. (2019). The postprandial inflammatory response is attenuated by a dietary structured lipid containing behenic acid. Journal of Functional Foods. 58:350- 354. 미소장
16 Das U. (2020). Arachidonic acid has anti-inflammatory and anti- diabetic actions in vitro and in vivo. Current Developments in Nutrition. 4:747-747. 미소장
17 Dinarello CA. (2000). Proinflammatory cytokines. Chest. 118:503- 508. 미소장
18 Dong L, Yin L, Zhang Y, Fu X and Lu J. (2017). Anti- inflammatory effects of ononin on lipopolysaccharide-stimulated RAW 264.7 cells. Molecular Immunology. 83:46-51. 미소장
19 Funk CD. (2001). Prostaglandins and leukotrienes: Advances in eicosanoid biology. Science. 294:1871-1875. 미소장
20 Gabay C. (2006). Interleukin-6 and chronic inflammation. Arthritis Research and Therapy. 8:1-6. 미소장
21 Habib S and Ali A. (2011). Biochemistry of nitric oxide. Indian Journal of Clinical Biochemistry. 26:3-17. 미소장
22 Hamed A, Mantawy E, El-Bakly W, Abdel-Mottaleb Y and Azab S. (2020). Methyl palmitate: The naturally occurring cardioprotective agent. Archives of Pharmaceutical Sciences Ain Shams University. 4:47-62. 미소장
23 Holanda Pinto S, Pinto L, Cunha G, Chaves M, Santos F and Rao V. (2008). Anti-inflammatory effect of α, β-amyrin, a pentacyclic triterpene from Protium heptaphyllum in rat model of acute periodontitis. Inflammopharmacology. 16:48-52. 미소장
24 Insuan O, Thongchuai B, Khamchun S, Insuan W, Daorueang D and Sansai P. (2022). Antidesma thwaitesianum Müll. Arg. fruit extract rich in 5-hydroxymethylfurfural exhibits anti- inflammatory effects in lipopolysaccharide-stimulated RAW264.7 macrophages. Journal of Herbmed Pharmacology. 11:278-285. 미소장
25 Islam MT, Ali ES, Uddin SJ, Shaw S, Islam MA, Ahmed MI, Shill MC, Karmakar UK, Yarla NS and Khan IN. (2018). Phytol: A review of biomedical activities. Food and Chemical Toxicology. 121:82-94. 미소장
26 Jananie R, Priya V and Vijayalakshmi K. (2011). Determination of bioactive components of Cynodon dactylon by GC-MS analysis. New York Science Journal. 4:16-20. 미소장
27 Jayawardena TU, Kim HS, Sanjeewa KA, Han EJ, Jee YH, Ahn GN, Rho JR and Jeon YJ. (2021). Loliolide, isolated from Sargassum horneri; abate LPS-induced inflammation via TLR mediated NF-κB, MAPK pathways in macrophages. Algal Research. 56:102297. https://www.sciencedirect.com/science/ article/abs/pii/S2211926421001168 (cited by 2024 February 27). 미소장
28 Kim AL, Labasi JM, Zhu Y, Tang X, McClure K, Gabel CA, Athar M and Bickers DR. (2005). Role of p38 MAPK in UVB-induced inflammatory responses in the skin of SKH-1 hairless mice. Journal of Investigative Dermatology. 124:1318- 1325. 미소장
29 Kim BH, Oh I, Kim JH, Jeon JE, Jeon B, Shin J and Kim TY. (2014). Anti-inflammatory activity of compounds isolated from Astragalus sinicus L. in cytokine-induced keratinocytes and skin. Experimental and Molecular Medicine. 46:e87. https:// www.nature.com/articles/emm2013157 (cited by 2024 January 10). 미소장
30 Kim EA, Kim SY, Kim JS, Oh JY, Kim HS, Yoon WJ, Kang DH and Heo SJ. (2019). Tuberatolide B isolated from Sargassum macrocarpum inhibited LPS-stimulated inflammatory response via MAPKs and NF-κB signaling pathway in RAW264.7 cells and zebrafish model. Journal of Functional Foods. 52:109-115. 미소장
31 Kim EA, Kim SY, Ye BR, Kim Js, Ko SC, Lee WW, Kim KN, Choi IW, Jung WK and Heo SJ. (2018). Anti-inflammatory effect of Apo-9′-fucoxanthinone via inhibition of MAPKs and NF-κB signaling pathway in LPS-stimulated RAW 264.7 macro phages and zebrafish model. International Immunopharmacology. 59:339-346. 미소장
32 Kim J, Kim JH, Bang SI, Shin H, Cho EJ and Lee S. (2022). Antioxidant activity of edible sprouts and phytosterol contents by HPLC/UV analysis. Horticulture, Environment, and Biotechnology. 63:769-778. 미소장
33 Kim J, Nguyen QN, Shin H, Kang KS and Lee S. (2021). In vitro Anti-inflammatory activities and phenolic acid analysis of tree sprout extracts. Korean Journal of Pharmacognosy. 52:257- 266. 미소장
34 Konishi I, Hosokawa M, Sashima T, Maoka T and Miyashita K. (2008). Suppressive effects of alloxanthin and diatoxanthin from Halocynthia roretzi on LPS-induced expression of pro- inflammatory genes in RAW264.7 cells. Journal of Oleo Science. 57:181-189. 미소장
35 Kumar PP, Kumaravel S and Lalitha C. (2010). Screening of antioxidant activity, total phenolics and GC-MS study of Vitex negundo. African Journal of Biochemistry Research. 4:191-195. 미소장
36 Lee CK, Kim H, Moon KH and Shin KH. (1998). Screening and isolation of antibiotic resistance inhibitors from herb materials-resistance inhibition of volatile components of Korean aromatic herbs. Archives of Pharmacal Research. 21:62-66. 미소장
37 Lee SM, Lee TH, Cui EJ, Baek NI, Hong SG, Chung IS and Kim JY. (2011). Anti-inflammatory effects of cowpea(Vigna sinensis K.) seed extracts and its bioactive compounds. Journal of the Korean Society for Applied Biological Chemistry. 54:710-717. 미소장
38 Liu X, Yin S, Chen Y, Wu Y, Zheng W, Dong H, Bai Y, Qin Y, Li J and Feng S. (2018). LPS-induced proinflammatory cytokine expression in human airway epithelial cells and macrophages via NF-κB, STAT3 or AP-1 activation. Molecular Medicine Reports. 17:5484-5491. 미소장
39 Marasinghe CK, Jung WK and Je JY. (2022). Anti- inflammatory action of ark shell(Scapharca subcrenata) protein hydrolysate in LPS-stimulated RAW264.7 murine macrophages. Journal of Food Biochemistry. 46:e14493. https://onlinelibrary. wiley.com/doi/full/10.1111/jfbc.14493 (cited by 2024 January 15). 미소장
40 Mazimba O. (2017). Umbelliferone: Sources, chemistry and bioactivities review. Bulletin of Faculty of Pharmacy, Cairo University. 55:223-232. 미소장
41 Miyasaka N and Hirata Y. (1997). Nitric oxide and inflammatory arthritides. Life Sciences. 61:2073-2081. 미소장
42 Mohammed GJ, Omran AM and Hussein HM. (2016). Antibacterial and phytochemical analysis of Piper nigrum using gas chromatography-mass spectrum and Fourier-transform infrared spectroscopy. International Journal of Pharmacognosy and Phytochemical Research. 8:977-996. 미소장
43 Munn LL. (2017). Cancer and inflammation. WIREs Mechanisms of Disease 9:e1370. https://wires.onlinelibrary.wiley.com/doi/abs/ 10.1002/wsbm.1370 (cited by 2024 March 31). 미소장
44 Myung DB, Lee JH, Han HS, Lee KY, Ahn HS, Shin YK, Song EJ, Kim BH, Lee KH and Lee SH. (2020). Oral intake of hydrangea serrata(Thunb.) ser. leaves extract improves wrinkles, hydration, elasticity, texture, and roughness in human skin: A randomized, double-blind, placebo-controlled study. Nutrients. 12:1588. https://www.mdpi.com/2072-6643/12/6/1588 (cited by 2024 April 11). 미소장
45 Nakamura S, Matsuda H and Yoshikawa M. (2011). Search for antidiabetic constituents of medicinal food. Journal of the Pharmaceutical Society of Japan. 131:909-915. 미소장
46 Newman DJ and Cragg GM. (2020). Natural products as sources of new drugs over the nearly four decades from 01/1981 to 09/ 2019. Journal of Natural Products. 83:770-803. 미소장
47 Newton K and Dixit VM. (2012). Signaling in innate immunity and inflammation. Cold Spring Harbor Perspectives in Biology. 4:a006049. https://cshperspectives.cshlp.org/content/4/3/a006049.short (cited by 2024 February 2). 미소장
48 Nore KG, Jørgensen MJ, Dyrhol-Riise AM, Jenum S and Tonby K. (2020). Elevated levels of anti-inflammatory eicosanoids and monocyte heterogeneity in Mycobacterium tuberculosis infection and disease. Frontiers in immunology. 11:579849. https://www.frontiersin.org/journals/immunology/ articles/10.3389/fimmu.2020.579849/full (cited by 2024 March 31). 미소장
49 Nunes CDR, Barreto Arantes M, Menezes de Faria Pereira S, Leandro da Cruz L, de Souza Passos M, Pereira de Moraes L, Vieira IJC and Barros de Oliveira D. (2020). Plants as sources of anti-inflammatory agents. Molecules. 25:3726. https:/ /www.mdpi.com/1420-3049/25/16/3726 (cited by 2024 Febrary 2). 미소장
50 Okur ME, Karadağ AE, Üstündağ Okur N, Özhan Y, Sipahi H, Ayla Ş, Daylan B, Demirci B and Demirci F. (2020). In vivo wound healing and in vitro anti-inflammatory activity evaluation of Phlomis russeliana extract gel formulations. Molecules. 25:2695. https://www.mdpi.com/1420-3049/25/11/ 2695 (cited by 2024 February 27). 미소장
51 Olukanni A. (2020). Antioxidant and in vitro anti-inflammatory activities of Albizia zygia(DC) JF mebr and the evaluation of its phytochemical constituents. Journal of Medicinal Plants Studies. 8:317-323. 미소장
52 Omeje K, Ozioko J and Opmeje H. (2018). Pharmacological potentials, characterization and fatty acids profile of Persea americana Mill.(avocardo) seed oil using gas chromatography- mass spectroscopy. Biochemistry and Analytical Biochemistry. 7:1000361. https://www.researchgate.net/profile/Kingsley-Omeje/... 미소장
53 Park S, Kim H, Lee HS and Chang CS. (2005). Taxonomic reconsideration of the Philadelphus schrenkii complex. Korean Journal of Plant Taxonomy. 35:247-272. 미소장
54 Rajeswari G, Murugan M and Mohan V. (2012). GC-MS analysis of bioactive components of Hugonia mystax L.(Linaceae). Research Journal of Pharmaceutical, Biological and Chemical Sciences. 3:301-308. 미소장
55 Ramadass V, Vaiyapuri T and Tergaonkar V. (2020). Small molecule NF-κB pathway inhibitors in clinic. International Journal of Molecular Sciences. 21:5164. https://www.mdpi.com/ 1422-0067/21/14/5164 (cited by 2024 April 11). 미소장
56 Seo J, Lee U, Seo S, Wibowo AE, Pongtuluran OB, Lee K, Han SB and Cho S. (2022). Anti-inflammatory and antioxidant activities of methanol extract of Piper betle Linn.(Piper betle L.) leaves and stems by inhibiting NF-κB/MAPK/Nrf2 signaling pathways in RAW 264.7 macrophages. Biomedicine and Pharmacotherapy. 155:113734. https://www.sciencedirect. com/science/article/pii/S0753332222011234 (cited by 2024 Fabruary 12). 미소장
57 Shalini K and Ilango K. (2021). Preliminary phytochemical studies, GC-MS analysis and in vitro antioxidant activity of selected medicinal plants and its polyherbal formulation. Pharmacognosy Journal. 13:648-659. 미소장
58 Sharma JN, Al-Omran A and Parvathy SS. (2007). Role of nitric oxide in inflammatory diseases. Inflammopharmacology. 15:252-259. 미소장
59 Shi J, Li CJ, Yang JZ, Ma J, Li Y, Chen H and Zhang DM. (2015). Monoterpenes from the leaves of Hydrangea paniculata and their hepatoprotective activities. Journal of Asian Natural Products Research. 17:512-518. 미소장
60 Shin KH, Chi HJ, Lim SS, Cho SH, Moon HI and Yu JH. (1997). Antimicrobial activities of volatile essential oils from Korean aromatic plants. Natural Product Sciences. 3:141-147. 미소장
61 Simon LS. (1999). Role and regulation of cyclooxygenase-2 during inflammation. The American Journal of Medicine. 106:37S-42S. 미소장
62 Smale ST. (2011). Hierarchies of NF-κB target-gene regulation. Nature Immunology. 12:689-694. 미소장
63 Sung YY, Kim MS, Yuk HJ, Kim SH, Lee GJ and Kim DS. (2023). Anti-obesity effects of Philadelphus tenuifolius extract via improvement of lipid metabolism in high-fat diet-induced obese mice. Planta Medica. 89:P-273. https://www.thieme- connect.com/products/ejournals/html/10.1055/s-0043-1774144(cited by 2024 April 11). 미소장
64 Taciak B, Białasek M, Braniewska A, Sas Z, Sawicka P, Kiraga Ł, Rygiel T and Król M. (2018). Evaluation of phenotypic and functional stability of RAW 264.7 cell line through serial passages. PLOS ONE. 13:e0198943. https://journals.plos.org/ plosone/article?id=10.1371/journal.pone.0198943 (cited by 2024 February 12). 미소장
65 Tsai FS, Lin LW and Wu CR. (2016). Lupeol and its role in chronic diseases. Drug Discovery from Mother Nature. 2016:145- 175. 미소장
66 Vadivel E and Gopalakrishnan S. (2011). GC-MS analysis of some bioactive constituents of Mussaenda frondosa Linn. International Journal of Pharma and Bio Sciences. 2:313-320. 미소장
67 Venn-Watson SK and Butterworth CN. (2022). Broader and safer clinically-relevant activities of pentadecanoic acid compared to omega-3: Evaluation of an emerging essential fatty acid across twelve primary human cell-based disease systems. PLOS ONE. 17:e0268778. https://journals.plos.org/plosone/ article?id=10.1371/journal.pone.0268778 (cited by 2024 February 27). 미소장
68 Viatour P, Merville MP, Bours V and Chariot A. (2005). Phosphorylation of NF-κB and IκB proteins: Implications in cancer and inflammation. Trends in Biochemical Sciences. 30:43-52. 미소장
69 Vuolteenaho K, Moilanen T, Knowles RG and Moilanen E. (2007). The role of nitric oxide in osteoarthritis. Scandinavian Journal of Rheumatology. 36:247-258. 미소장
70 Wang J, Liu Y, Gu Y, Liu C, Yang Y, Fan X, Yang H, Liu Y and Ma T. (2023). Function and inhibition of P38 MAP kinase signaling: Targeting multiple inflammation diseases. Biochemical Pharmacology:115973. https:// www.sciencedirect.com/science/article/abs/pii/S000629522300566X (cited by 2024 March 30). 미소장
71 Wink DA, Hines HB, Cheng RY, Switzer CH, Flores-Santana W, Vitek MP, Ridnour LA and Colton CA. (2011). Nitric oxide and redox mechanisms in the immune response. Journal of Leukocyte Biology. 89:873-891. 미소장
72 Xiao P. (1989). Zhongguo ben cao tu lu(Vol. 7). Ren min wei sheng chu ban she. Beijing, China. p.68. 미소장
73 Yadav A, Saini V and Arora S. (2010). MCP-1: Chemoattractant with a role beyond immunity: A review. Clinica Chimica Acta. 411:1570-1579. 미소장
74 Yang GS, Lee KJ, Lee MH, Ham IH and Choi HY. (2012). Inhibition of lipopolysaccharide-induced nitric oxide and prostaglandin E2 production by chloroform fraction of Cudrania tricuspidata in RAW 264.7 macrophages. BMC Complementary and Alternative Medicine. 12:1-7. 미소장
75 Zhang D, Guo H, Feng W and Qiu H. (2019). LAMC2 regulated by microRNA-125a-5p accelerates the progression of ovarian cancer via activating p38 MAPK signalling. Life Sciences. 232:116648. https://www.sciencedirect.com/science/ article/abs/pii/S0024320519305740 (cited by 2024 February 15). 미소장

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