본문 바로가기 주메뉴 바로가기
22대 대한민국 국회 국회정보길라잡이 국회의원검색
회원가입 로그인
HOME

정보검색

소장정보 검색

국회도서관 홈으로 정보검색 소장정보 검색
결과 내 검색 동의어 포함
결과 내 검색 동의어 포함

-

초록보기

Background: Anesthetic agents are potential modifiable factors that can mitigate chronic postsurgical pain (CPSP) development. This study aimed to investigate the association between propofol-based total intravenous anesthesia (TIVA) and the occurrence of CPSP following video-assisted thoracoscopic surgery (VATS) for lung cancer resection.

Methods: This single-center retrospective cohort study included adult patients with lung cancer who underwent elective VATS between January 2018 and December 2022. Patients were divided based on the maintenance anesthetic used (propofol vs. sevoflurane). The primary outcome was the presence of CPSP, defined as any level of surgical site pain recorded within 3–6 months postoperatively. The authors investigated the association between anesthetic agents and CPSP using propensity score matching with stabilized inverse probability of treatment weighting (sIPTW) to adjust for confounders. Additionally, multivariable logistic regression was used to further adjust for intraoperative opioid use that sIPTW could not account for. The robustness of these associations was evaluated using the E-value.

Results: Of the 833 patients analyzed, 461 received propofol and 372 sevoflurane. The overall incidence of CPSP was 43.3%. After sIPTW, the use of TIVA was significantly associated with a lower incidence of CPSP (odds ratio [OR]: 0.75, 95% confidence interval [CI]: 0.57–0.99, P = 0.041), and remained significant after adjusting for intraoperative remifentanil equivalent dose (OR: 0.73, 95% CI: 0.55–0.96, P = 0.026). The E-values were 1.08 and 1.17, respectively.

Conclusions: Propofol-based TIVA is associated with reduced CPSP occurrence in VATS for lung cancer. Further prospective studies are needed to confirm the results.

권호기사

권호기사 목록 테이블로 기사명, 저자명, 페이지, 원문, 기사목차 순으로 되어있습니다.
기사명 저자명 페이지 원문 목차
Targeting nerve growth factor for pain relief : pros and cons Sahar Jaffal, Raida Khalil p. 288-298

Methylcobalamin as a candidate for chronic peripheral neuropathic pain therapy : review of molecular pharmacology action Amilia Ramadhani, Indwiani Astuti, Maria Goreti Widiastuti, Nunuk Purwanti p. 299-309

Low level laser therapy alleviates mechanical allodynia in a postoperative and neuropathic pain model and alters the levels of inflammatory factors in rats Xuehao Han, Kyeong-cheol Jang, Woong Mo Kim, Hyung Gon Lee p. 310-319

Down-regulation of microRNA-382-5p reduces neuropathic pain by targeting regulation of dual specificity phosphatase-1 Anjie Xu, Huili Shen, Shasha Mei, Zhongwei Wang, Qiuyi Xie, Huaqing Cui, Yunchao Chu, Baihe Feng p. 320-331

Effect of ultrasound-guided ilioinguinal-iliohypogastric nerve block on chronic pain in patients undergoing open inguinal hernia surgery under spinal anesthesia : a randomized double-blind study Rajendra Kumar Sahoo, Amit Pradhan, Priyadarsini Samanta, Laxman Kumar Senapati, Ganesh Chandra Satapathy p. 332-342

Assessment of ultrasound-guided intercostal nerve block for acute herpes zoster and its' possible prophylaxis for postherpetic neuralgia : a retrospective and case-controlled trial Xiuhua Li, Rong Yuan, Yanwei Yang, Zhenlong Qin, Runqiao Fu p. 343-353

Impact of general anesthesia type on chronic postsurgical pain following video-assisted thoracoscopic surgery for lung cancer : a retrospective propensity-matched cohort study Soo-Hyuk Yoon, Seungeun Choi, Susie Yoon, Kwon Joong Na, Jaehyon Bahk, Ho-Jin Lee p. 354-366

Efficacy and safety of low-dose naltrexone for the management of fibromyalgia : a systematic review and meta-analysis of randomized controlled trials with trial sequential analysis Akhil Deepak Vatvani, Pratik Patel, Timotius Ivan Hariyanto, Theo Audi Yanto p. 367-378

추천서가 (다양한 추천 자료를 만나보세요)

권호기사보기

권호기사 목록 테이블로 기사명, 저자명, 페이지, 원문, 기사목차 순으로 되어있습니다.
기사명 저자명 페이지 원문 기사목차