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Objective The purpose of this study was to provide information on the international trends in Humulus japonicus by analyzing recently reported papers and theses.
Methods Papers on the medicinal in vivo and in vitro activities of Humulus japonicus were reviewed and analyzed. Data on the publication year, research and experimental methods, and subjects were extracted and summarized.
Results Twenty-eight papers with recent experimental studies and clinical trials related to Humulus japonicus were included. The following results were obtained from this study.
1. An average of 2.8 papers were published annually from 2014 to 2023.
2. There were 27 experimental studies and one clinical trials during the study period.
3. Among the studies, there were 13 in vivo, seven in vitro, and seven with both types of experiments.
4. Based on the subject area, studies on neuropsychiatric activity were the most numerous, totaling six reports.
Conclusions Humulus japonicus has been studied for various activities, including neuropsychiatric, anti-inflammatory, liver function-related, digestive system-related, antibacterial, anti-obesity, anti-aging, and antioxidant effects. However, more clinical research is needed to further explore its medicinal uses.*표시는 필수 입력사항입니다.
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