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22대 대한민국 국회 국회정보길라잡이 국회의원검색
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정보검색

소장정보 검색

국회도서관 홈으로 정보검색 소장정보 검색
결과 내 검색 동의어 포함
결과 내 검색 동의어 포함

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초록보기

Background: Oryeongsan (Wulingsan, Goreisan) has long been used for the treatment of impaired body fluid metabolism. However, the action mechanisms have not been clearly defined. Recently, effects of Oryeongsan on the body fluid and Na+ metabolism and the action mechanisms have been shown more clearly. The present review focuses on the recent findings on the effects of Oryeongsan in the cardio-renal system in relation with body fluid metabolism and action mechanisms leading to a decrease in blood pressure in animal models of hypertension.

Methods: The new and recent findings were searched by using searching systems including PubMed-NCBI and Google-Scholar.

Results: Oryeongsan induced an increase in glomerular filtration rate, and natriuresis and diuresis with a decreased osmolality and resulted in a contraction of the body fluid and Na+ balance. These findings were associated with a suppression of abundance of Na+-H+-exchanger isoform 3 expression and V2 receptor/aquaporin2 water channel signaling pathway in the kidney. Further, treatment with Oryeongsan accentuated atrial natriuretic peptide secretion in the atria from spontaneously hypertensive rats in which the secretion was suppressed. In addition, Oryeongsan ameliorated impaired vasodilation in spontaneously hypertensive rats.

Conclusion: The effects of Oryeongsan in the kidney, atria, and vessel were accompanied by a suppression of AT1 receptor and concurrent accentuation of abundance of AT2/Mas receptors expression and modulation of the natriuretic peptide system in these organs from hypertensive rats. The review shows multiple sites of action of Oryeongsan and mechanisms involved in the regulation of volume and pressure homeostasis in the body.

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기사명 저자명 페이지 원문 목차
(An) evidence map on traditional medicine across health outcomes Lin Ang, Eunhye Song, Miek C Jong, Terje Alræk, Barbara Wider, Tae-Young Choi, Ji Hee Jun, Boram Lee, Yujin Choi, Hye Won Lee ... [et al.] p. 1-10
Herbal medicine Oryeongsan (Wulingsan) : cardio-renal effects via modulation of renin-angiotensin system and atrial natriuretic peptide system Ho Sub Lee, Hye Yoom Kim, You Mee Ahn, Kyung Woo Cho p. 1-7
Effectiveness and safety of Liriope Tuber (Liriopis seu Ophiopogonis Tuber, maidong) included traditional herbal medicine for patients with paroxysmal atrial fibrillation : a systematic review, meta-analysis, and network analysis Hanbit Jin, Sukjong Kang, Dasol Park, Yeun-Ja Mun, Jungtae Leem p. 1-14
Adding thread-embedding acupuncture to auricular acupuncture enhances short-term weight reduction in overweight and obesity : a double-blinded, randomized, sham-controlled trial Dieu-Thuong Thi Trinh, Quoc-Viet Kieu, An Hoa Tran, Minh-Man Pham Bui, Nguyen Lam Vuong p. 1-7
Using PRECIS-2 in Chinese herbal medicine randomized controlled trials for irritable bowel syndrome : a methodological exploration based on literature Minjing Luo, Yingqiao Wang, Jinghan Huang, Yilin Li, Wenjie Li, He Li, Zhihan Liu, Meijun Liu, Yunci Tao, Jianping Liu, Yutong Fei p. 1-6
Pharmacopuncture therapy for adhesive capsulitis : a pragmatic randomized controlled pilot study Doori Kim, Kyoung Sun Park, Sun-A Kim, Ji Yeon Seo, Hyun-Woo Cho, Yoon Jae Lee, Changsop Yang, In-Hyuk Ha, Chang-Hyun Han p. 1-10
(A) synergistic effect of herb and acupuncture on the methamphetamine Jin Gyeom Lee, Yuchi Li, Nam Jun Kim, Han Byeol Jang, Chae Ha Yang, Hee Young Kim, Seong Shoon Yoon, Suchan Chang, Seon-Ju Jeong, Sang Chan Kim, Bok Suk Sa, Bong Hyo Lee p. 1-10
Peripheral Rho-associated protein kinase activation mediates acupuncture analgesia Ji-Yeun Park, Jae-Hwan Jang, Yang-Hwa Kang, Songhee Jeon, Seung-Nam Kim, Yeon-Hee Ryu, Hi-Joon Park p. 1-8
Protective effect of Korean red ginseng water extract on levothyroxine-induced hyperthyroidism and propylthiouracil-induced hypothyroidism in rats Lei Huang, Won Young Jang, Ji Hye Yoon, Zhenyan Piao, Jinghan Su, Dong Seon Kim, Ki Woong Kwon, Ji Won Kim, Sang Hee Park, Sunggyu Kim, Jong-Hoon Kim, Jae Youl Cho p. 1-10
How can meta-research be used to evaluate and improve the quality of research in the field of traditional, complementary, and integrative medicine? Jeremy Y. Ng, Myeong Soo Lee, Jian-ping Liu, Amie Steel, L. Susan Wieland, Claudia M. Witt, David Moher, Holger Cramer p. 1-8
(A) practical guide to implementing artificial intelligence in traditional East Asian medicine research Hyojin Bae, Sa-Yoon Park, Chang-Eop Kim p. 1-11

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