[표지]

발간사 / 손여원

목차

발기부전치료제 및 유사물질 - 70종 - 19

LC-Q-TOF-MS 분석조건 21

LC-MS/MS 분석조건 22

LC-TOF-MS 분석조건 23

(1) 2-Hydroxypropylnortadalafil 24

(2) Acetaminotadalafil 25

(3) Acetil acid 26

(4) Acetylvardenafil 27

(5) Aminotadalafil 28

(6) Avanafil 29

(7) Benzylsildenafil 30

(8) Carbodenafil 31

(9) Chlorodenafil 32

(10) Chloropretadalafil 33

(11) Cinnamyldenafil 34

(12) Cyclopentinafil 35

(13) Cyclopentyltadalafil 36

(14) Dapoxetine 37

(15) Demethyltadalafil 38

(16) Demethylpiperazinylsildenafil sulfonic acid 39

(17) Desmethylcarbodenafil 40

(18) Desulfovardenafil 41

(19) Diethylaminopretadalafil 42

(20) Dichlorodenafil 43

(21) Dimethylacetildenafil 44

(22) Demethylhongdenafil 45

(23) Dimethylsildenafil 46

(24) Dimethylthiosildenafil 47

(25) Dioxohongdenafil 48

(26) Dithiodesmethylcarbodenafil 49

(27) Epi-Aminotadalafil 50

(28) Gendenafil 51

(29) Homosildenafil 52

(30) Homotadalafil 53

(31) Homothiomethylsildenafil(Methylhydroxyhomosildenafil) 54

(32) Hongdenafil 55

(33) Hydroxychlorodenafil 56

(34) Hydroxyhomosildenafil 57

(35) Hydroxyhongdenafil 58

(36) Hydroxythiohomosildenafil 59

(37) Hydroxyvardenafil 60

(38) Icariin 61

(39) Imidazosagatriazinone 62

(40) Lodenafilcarbonate 63

(41) Mirodenafil 64

(42) Mutaprodenafil 65

(43) N-Butyltadalafil 66

(44) N-Desmethylacetildenafil 67

(45) N-Desmethylsildenafil 68

(46) N-Desethylvardenafil 69

(47) Nitrodenafil 70

(48) Norneosildenafil 71

(49) Norneovardenafil 72

(50) Ocytylnortadalafil 73

(51) Oxohongdenafil 74

(52) Piperidinohongdenafil 75

(53) Propoxyphenylthioaildenafil 76

(54) Propoxyphenylthiohomosildenafil 77

(55) Propoxyphenylthiohydroxyhomosildenafil 78

(56) Propoxyphenylthiosildenafil 79

(57) Pseudovardenafil 80

(58) Pyrazole-N-desmethylsildenafil 81

(59) Sildenafil 82

(60) Sildenafil coupled 83

(61) Tadalafil impurity E 84

(62) Tadalafil 85

(63) Thiohomosildenafil 86

(64) Thioquinapiperifil 87

(65) Thiosildenafil 88

(66) trans-Cyclopentyltadalafil 89

(67) Udenafil 90

(68) Vardenafil 91

(69) Xanthoanthrafil 92

(70) Yohimbine 93

스테로이드 - 47종 - 95

LC-Q-TOF-MS 분석조건 97

LC-TOF-MS 분석조건 98

LC-MS/MS 분석조건 99

(1) 6α-Methylprednisolone aceponate 100

(2) 11α-OH-progesterone-hemisyccinate 101

(3) Amcinonide 102

(4) Beclomethasone-17-propionate 103

(5) Beclomethasone-21-acetate 104

(6) Beclomethasone-21-hemisuccinate 105

(7) Beclomethasone-21-propionate 106

(8) Beclomethasone dipropionate 107

(9) Beclomethasone 108

(10) Betamethasone-17-valerate 109

(11) Betamethasone-21-acetate 110

(12) Betamethasone-21-hemisuccinate 111

(13) Betamethasone-21-valerate 112

(14) Betamethasone dipropionate 113

(15) Betamethasone 114

(16) Budesonide 115

(17) Clenbuterol HCl 116

(18) Clobetasol-17-propionate 117

(19) Cortisone-21-acetate 118

(20) D(-)-Norgesterel 119

(21) Dexamethasone-21-acetate 120

(22) Dexamethasone-21-hemisuccinate 121

(23) Dexamethasone 122

(24) Fludrocortisone acetate 123

(25) Fluticasone furoate 124

(26) Fluticasone propionate 125

(27) Hydrocortisone-17-acetate 126

(28) Hydrocortisone-17-valerate 127

(29) Hydrocortisone-21-acetate 128

(30) Hydrocortisone-21-valerate 129

(31) Hydrocortisone 130

(32) Medroxyprogesterone-17-acetate 131

(33) Megesterol acetate 132

(34) Methylprednisolone 133

(35) Norethisterone 134

(36) Norethisterone acetate 135

(37) Prednicarbate 136

(38) Prednisolone-21-acetate 137

(39) Prednisolone 138

(40) Prednisone 139

(41) Prednisone-21-acetate 140

(42) Testosterone-17-propionate 141

(43) Testosterone 142

(44) Testosterone-17-propionate 143

(45) Testosterone-17-valerate 144

(46) Triamcinolone acetonide 145

(47) Triamcinolone diacetate 146

단백동화스테로이드 - 23종 - 147

LC-Q-TOF-MS 분석조건 149

LC-TOF-MS 분석조건 150

LC-MS/MS 분석조건 151

(1) 1-Androstendione 152

(2) 19-Norandrostenone 153

(3) Bolasterone 154

(4) Boldenone(M) 155

(5) Boldenone 156

(6) Boldione 157

(7) Calusterone 158

(8) Clostebol 159

(9) Danazol(M) 160

(10) Fluoxymesterone 161

(11) Formebolone 162

(12) Methandienone(M) 163

(13) Methandrostenololne 164

(14) Methenolone 165

(15) Methylnortestosterone 166

(16) Mibolerone 167

(17) Nandrolone(M1) 168

(18) Nandrolone(M2) 169

(19) Nandrolone 170

(20) Norbolethone 171

(21) Norclosterbol 172

(22) Norethandrolone 173

(23) Oral-turinabol(M) 174

항히스타민 - 23종 - 175

LC-LC-Q-TOF-MS 분석조건 177

LC-MS/MS 분석조건 178

(1) Acrivastine 179

(2) Astemizole HCl 180

(3) Azelastine HCl 181

(4) Bambuterol 182

(5) Bromopheniramine 183

(6) Cetrizine 184

(7) Chlorpheniramine 185

(8) Clemastine 186

(9) Cyproheptadine 187

(10) Desloratadine 188

(11) Dimenhydrinate(Diphenhydramine + Chlorotheophylline) 189

(12) Diphenhydramine 190

(13) Ebastine 191

(14) Epinastine 192

(15) FexOFenadine 193

(16) Hydroxyzine 194

(17) Ketotifen fumarate salt 195

(18) Levocetirizine 196

(19) Loratadine 197

(20) Olopatadine 198

(21) Promethazine 199

(22) Terfenadine 200

(23) Triprolidine 201

진통제 - 19종 - 203

LC-TOF-MS 분석조건 205

LC-MS/MS 분석조건 206

(1) 4-Dimethylaminoantipyrine 207

(2) Acetaminophen 208

(3) Aspirin 209

(4) Carbamazepine 210

(5) Celecoxib 211

(6) Diclofenac 212

(7) Dipyrone 213

(8) FenoprOFen 214

(9) FlurbiprOFen 215

(10) IbuprOFen 216

(11) Indomethacin 217

(12) KetoprOFen 218

(13) Ketorolac 219

(14) Meclofenamate 220

(15) Mefenamic acid 221

(16) Meloxicam 222

(17) Naproxen 223

(18) Piroxicam 224

(19) Sulindac 225

이뇨제 227

〈LC-TOF-MS 분석조건〉 229

〈LC-MS/MS 분석조건〉 230

(1) Acetazolamide(Group 1) 232

(2) Amiloride HCl(Group 2) 233

(3) Azosemide(Group 2) 234

(4) Bendroflumethiazide(Group 1) 235

(5) Bumetanide(Group 2) 236

(6) Chlorothalidone(Group 1) 237

(7) Chlorothiazide(Group 1) 238

(8) Cyclothiazide(Group 1) 239

(9) Eplerenone(Group 2) 240

(10) Ethacrynic acid(Group 2) 241

(11) Furosemide(Group 2) 242

(12) Hydrochlorothiazide(Group 1) 243

(13) Hydroflumethiazide(Group 1) 244

(14) Indapamide(Group 1) 245

(15) Methazolamide(Group 2) 246

(16) Methyclothiazide(Group 1) 247

(17) Metolazone(Group 1) 248

(18) Piretanide(Group 2) 249

(19) Spironolactone(Group 2) 250

(20) Torsemide(Group 1) 252

(21) Triamterene(Group 2) 253

(22) Trichloromethiazide(Group 1) 254

(23) Xipamide(Group 2) 255

비만치료제 257

〈LC-Q-TOF-MS 분석조건〉 259

〈LC-MS/MS 분석조건〉 260

(1) Atenolol 262

(2) Benzylsibutramine 263

(3) β-Methylphenethylamine 264

(4) Bisacodyl 265

(5) Bupropion HCl 266

(6) Caffeine 267

(7) Captopril 268

(8) Chlorosibutramine 269

(9) Desmethylsibutramine 270

(10) Didesmethylsibutramine 271

(11) Ephedrine HCl 272

(12) Fluoxetine HCl 273

(13) Levothyroxine 274

(14) Liothyronine 276

(15) Modafinil 278

(16) Orlistat 279

(17) Paroxetine 280

(18) Phenolphtalein 281

(19) Phenytoin sodium 282

(20) Propranolol 283

(21) Pseudoephedrine HCl 284

(22) Rimonabant 285

(23) Sennoside A 286

(24) Sennoside B 287

(25) Sertraline HCl 288

(26) Sibutramine 289

(27) Theophylline 290

마약류 291

〈LC-TOF-MS 분석조건〉 293

〈LC-MS/MS 분석조건〉 294

(1) 2C-I 296

(2) 5-MeO-Dipt HCl 297

(3) A-834735 298

(4) Alfentanil HCl 299

(5) Alprazolam 300

(6) AM2201 301

(7) AM2233 302

(8) Amphetamine 303

(9) α-PVT(alpha-pyrrolidinopentiothiophenone) 304

(10) Benzylpiperazine 2HCl(BZP) 305

(11) Bromazepam 306

(12) Carisoprodol 307

(13) CB-13 308

(14) Chlordiazepoxide HCl 309

(15) Clobazam 310

(16) Clonazepam 311

(17) Codeine phosphate hydrate 312

(18) Dextromethorphan HBr 313

(19) Diazepam 314

(20) Diethylpropion HCl 316

(21) Dihydrocodeine Bitartrate 317

(22) Estazolam 318

(23) Fenfluramine HCl 319

(24) Fentanyl citrate 320

(25) Flunitrazepam 321

(26) Flurazepam HCl 322

(27) GHB 323

(28) Hexobarbital 324

(29) Hydrocodone Bitartrate 326

(30) Hydromorphone HCl 328

(31) JWH 018 329

(32) JWH 019 330

(33) JWH 073 331

(34) JWH 081 332

(35) JWH 122 333

(36) JWH 210 334

(37) JWH 250 335

(38) Ketamine 336

(39) m-Hydroxybenzylpiperazine 337

(40) Lorazepam 338

(41) Mazindol 339

(42) MDBP 340

(43) MDMA HCl 341

(44) MeOPP(1-(4-methoxyphenyl)piperazine) 342

(45) Methamphetamine HCl 343

(46) Methaqualone 344

(47) Methylphenidate HCl 345

(48) Midazolam 346

(49) Morphine HCl 347

(50) Norfenfluramine HCl 348

(51) Oxycodone HCl 349

(52) p-Hydroxybenzylpiperazine 350

(53) Pentazocine 351

(54) Pentobarbital 352

(55) Phendimetrazine tartrate 353

(56) Phenobarbital 354

(57) Phentermine HCl 355

(58) Sufentanil citrate 356

(59) Temazepam 357

(60) Triazolam 358

(61) XLR11(5-Fluoro-UR-144) 359

(62) Zolpidem tartrate 360

갱년기치료제 361

〈LC-TOF-MS 분석조건〉 363

〈LC-MS/MS 분석조건〉 364

(1) Estrone 365

(2) Estro sulfate 366

(3) β-Estradiol-17-cypionate 367

(4) β-Estradiol-17-valerate 368

(5) Medroxyprogesterone acetate 369

(6) Norethisterone acetate 370

(7) Raloxifene HCl 371

고지혈증치료제 373

〈LC-TOF-MS 분석조건〉 375

〈LC-MS/MS 분석조건〉 376

(1) Atorvastatin 377

(2) Ciprofibrate 378

(3) Clinofibrate 379

(4) Fluvastatin 380

(5) Gemfibrozil 381

(6) Pantethine 382

(7) Pravastatin 383

(8) Rosuvastatine 384

고혈압치료제 385

〈LC-TOF-MS 분석조건〉 387

〈LC-MS/MS 분석조건〉 388

(1) Amlodipine 390

(2) Benazepril 392

(3) Bisoprolol 393

(4) Candesartan 394

(5) Carteolol 395

(6) Carvedilol 396

(7) Celiprolol 397

(8) Clonidine 398

(9) Doxazosin 399

(10) Diltiazem 400

(11) Enalapril 402

(12) Felodipine 403

(13) Hydralazine 404

(14) Isradipine 405

(15) Lisinopril 406

(16) Losartan 407

(17) Minoxidil 408

(18) Metoprolol 410

(19) Nadolol 411

(20) Nicardipine 412

(21) Nifendipine 413

(22) Nisoldipine 414

(23) Nitrendipine 415

(24) Olmesartan 416

(25) Penbutolol 418

(26) Phentolamine 419

(27) Pindolol 420

(28) Prazosin 421

(29) Ramipril 422

(30) Telmisartan 423

(31) Terazosin 424

(32) Valsartan 425

(33) Warfarin 426

당뇨병치료제 427

〈LC-TOF-MS 분석조건〉 429

〈LC-MS/MS 분석조건〉 430

(1) Buformin HCl 431

(2) Glibenclamide 432

(3) Gliclazide 433

(4) Glimepiride 434

(5) Glipizide 436

(6) Metformine 437

(7) Mitiglinide 438

(8) Nateglinde 439

(9) Pioglitazone HCl 440

(10) Repaglinide 441

(11) Rosiglitazone 442

(12) Tolbutamide 443

참고문헌 445

판권기 540

LC-Q-TOF-MS 분석결과 480

LC-MS/MS 분석결과 502