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22대 대한민국 국회 국회정보길라잡이 국회의원검색
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국회도서관 홈으로 정보검색 소장정보 검색
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Abstract 8

I. 서론 10

1. 연구의 필요성 10

2. 연구 목적 13

3. 연구 가설 13

4. 용어의 정의 14

II. 문헌고찰 18

1. 만성 C형 간염의 약물요법 18

2. 만성 C형 간염 환자의 항바이러스제 복용이행에 영향을 미치는 요인 22

3. 약물 복용이행을 위한 교육프로그램 25

III. 연구의 이론적 기틀 29

IV. 연구 방법 36

1. 연구 설계 36

2. 연구 대상 37

3. 연구도구 39

4. 연구진행절차 42

가. 항바이러스제 복용이행 교육프로그램 개발 43

나. 보조연구자 훈련 및 예바조사 56

다. 사전조사 57

라. 항바이러스제 복용이행 교육프로그램 수행 57

마. 사후조사 59

5. 자료수집 및 윤리적 고려 60

6. 자료 분석 방법 61

V. 연구결과 63

1. 대상자의 일반적 특성, 질병관련 특성 및 동질성 검증 63

2. 대상자의 사전 종속변수의 동질성 검증 64

3. 가설 검증 66

VI. 논의 70

1. 만성 C형 간염 환자를 위한 항바이러스제 복용이행 교육프로그램 개발 70

2. 만성 C형 간염 환자를 위한 항바이러스제 복용이행 교육프로그램 효과분석 76

VII. 결론 및 제언 82

References 84

Appendix 97

Appendix 1. 프로그램 초안 97

Appendix 2. 대상자와의 면담 98

Appendix 3. 소책자(대상자 제공용) 100

Appendix 4. 항바이러스제 복용일지(대상자 제공용) 108

Appendix 5. 프로그램 내용타당도 평가 110

Appendix 6. 교육 계획서 111

Appendix 7. 설명문 및 동의서 135

Appendix 8. 설문지 138

Appendix 9. 연구자 측정 기록지(질병관련 특성) 144

Appendix 10. 도구사용 숭인 145

Appendix 11. 부경대학교 기관생명윤리 위원회 심사결과 통지서 147

표목차

Table 1. Characteristics of DAA 21

Table 2. Review of Studies for Medication Adherence 26

Table 3. Contents of the Antiviral Agents Medication Adherence Education Program 53

Table 4. Overview of Antiviral Agents Medication Adherence Education Program 59

Table 5. Homogeneity Test for General Characteristics and Diseases-related... 65

Table 6. Homogeneity Test of Dependent Variables 66

Table 7. Effectiveness of the Antiviral Agents Medication Adherence Education... 69

그림목차

Figure 1. King's Transaction Process Model 30

Figure 2. Nurse-Patient Interaction that Lead to Transaction 31

Figure 3. Conceptual Framework for the Study 35

Figure 4. Nonequivalent Control Group Pretest-Posttest Design 36

Figure 5. Flow Chart of the Enrollment of the Participants 39

Figure 6. Flow Chart of Program Development 44

초록보기

 The purpose of this study was to develop and verify the effectiveness of the goal-attainment-theory-based antiviral agents medication adherence education program for chronic hepatitis C patients.

A nonequivalent control group pretest-posttest design was used in this study. Data were collected from December 2019, to March 2020, with a control group of 35 patients from General Hospital A and an experimental group of 28 patients from General Hospital B.

The data analysis was performed using an SPSS/WIN 25.0 program, and either an independent t-test, χ²-test, or Fisher's exact test was used for preliminary testing regarding homogeneity. To test the hypotheses, the normality of the differences between the pretest and posttest data of the intervention and control groups was assessed using the Kolmogorov-Smirnov test and, subsequently, the Mann-Whitney U test, because the data were not normally distributed.

The results were as follows:

1) This study has showed that patients' knowledge of hepatitis C would improve more among patients in the experimental group than among patients in the control group after completion of the antiviral agents medication adherence education program(Z＝-5.91, p＜.001).

2) This study has showed that medication adherence self-efficacy would improve more for patients in the experimental group than for patients in the control group after completion of the antiviral agents medication adherence education program(Z＝-5.02, p＜.001).

3) This study has showed that medication adherence rate would improve more among patients in the experimental group than among patients in the control group after completion of the antiviral agents medication adherence education program(t＝-3.88, p＜.001).

4) This study has showed that medication misuse behavior would decrease more among patients in the experimental group than among patients in the control group after completion of the antiviral agents medication adherence education program(Z＝-5.00, p＜.001).

5) This study has showed that satisfaction with the healthcare provider would improve more for patients in the experimental group than for patients in the control group after completion of the antiviral agents medication adherence education program(Z＝-6.61, p＜001).

This study has showed the effectiveness of the goal attainment theory based antiviral agents medication adherence education program for chronic hepatitis C patients with regard to patients' medication adherence in clinic by a gastroenterology nurse practitioner. Therefore, it is hoped that the medication adherence education program developed and applied in this study will be utilized as a nursing intervention for the healthcare of chronic hepatitis C patients and be further developed for the wider care of patients with viral hepatitis. Further studies are warranted to explore the role of behavioral modification mediating between chronic liver disease risk management and health-related quality of life in this population.

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