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국회도서관 홈으로 정보검색 소장정보 검색

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Raw meat of mackerel (Scomber japonicus) was salted by refined, sun-dried, bamboo, and KCl-added bamboo salts. Antimutagenic activity on N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) in Ames test and growth inhibitory effects of AGS human gastric and HT-29 human colon adenocarcinoma cells were investigated using methanol extracts of the salted mackerels. Mackerel salted sun-dried, bamboo, and KCl-added bamboo salts used increased the antimutagenic activities against MNNG, however, the sample treated with refined salt reduced the antimutagenic activity. Inhibitory effects of the salted-mackerels on the growth of human cancer cells were increased as dose dependent pattern. Mackerel salted with refined salt activated the growth of AGS human gastric adenocarcinoma cells, but mackerel salted with sun-dried, bamboo, and KCl-added bamboo salts kept or increased anticancer effect compared to the raw mackerel. Mackerel salted with KCl-added bamboo salt led to the highest antimutagenic and anticancer activities. These results suggest that antimutagenic and anticancer effects of mackerel during manufacturing of the salted-mackerel could be enhanced by using different kind of salts such as bamboo, or KCl-added bamboo salts.

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참고문헌 (17건) : 자료제공( 네이버학술정보 )

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번호 참고문헌 국회도서관 소장유무
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