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국회도서관 홈으로 정보검색 소장정보 검색

초록보기

및 결론본 연구는 4주령 ICR 수컷 마우스에 대두유와 쇠기름에 1% CLA를 첨가한 식이로 4주 동안 사육하여 체중, 내장지방과 부고환지방 조직 무게, 혈장과 간의 중성지방 농도, SCD1의 유전자 발현과 △9 desaturase index를 관찰하여 얻은 결과는, 대두유와 쇠기름에 첨가한 CLA는 체중과 식이이용효율에는 영향을 미치지 않았으나 부고환지방 조직과 혈장에서의 중성지방 농도를 유의적으로 감소시켰다. SCD1의 발현과 △9 desaturase index는 기름의 종류나 CLA의 첨가에 따라 차이가 없었다.

This study investigated the effects of conjugated linoleic acid(CLA) on the fat deposition, triglyceride levels and the expression of stearoyl-CoA desaturase 1(SCD1) in the livers of male ICR mice that were fed with either soybean oil or beef tallow supplemented with CLA. Mice weighing 25~30 g were divided into four groups; soybean oil(SBO), and SBO supplemented with 1% CLA(SBOC), beef tallow(BT) and BT supplemented with 1% CLA(BTC). Each group consisted of 10 mice that were fed the experimental diets for 4 weeks. The experimental diets consisted of 64% carbohydrate, 20% protein, and 16% fat in terms of their contributions to total calories. All other nutrients were identical in the diets. Triglyceride measurements were completed using a kit. Fatty acid compositions were analyzed in the liver using gas chromatography. The levels of SCD1 expression were analyzed by RT-PCR in the liver. No significant differences were found for food intake level, body weight and food efficiency among the experimental groups. However, the weights of epididymal fat pads and plasma triglyceride levels were significantly lower in SBOC and BTC(p<0.05) compared to the SBO and BT groups. These effects were similar in the CLA supplemented groups. The expression level of SCD1 gene and △9 desaturase index were not significantly different, regardless of the fat used for CLA supplementation. Based on these results, addition of CLA showed decreasing effects on the fat depots weight and the concentration of triglyceride regardless of the fat sources. The SCD 1 gene expression and △9 desaturase index were not influenced by the types of fats with respect to the CLA effects.

권호기사

권호기사 목록 테이블로 기사명, 저자명, 페이지, 원문, 기사목차 순으로 되어있습니다.
기사명 저자명 페이지 원문 목차
지방 급원을 달리한 식이에 첨가된 CLA가 지방조직과 stearoyl-CoA desaturase 1(SCD 1) 발현에 미치는 영향 강금지 ;이세나 pp.245-252

차가버섯 추출물의 종양 전이 억제 효과 윤택준 ;문원국 ;이광호 pp.253-258

생강 추출물 투여가 전구염증성 사이토카인 IFN-γ와 항염증성 사이토카인 IL-10 분비량에 미치는 영향 류혜숙 pp.259-264

실크펩티드 첨가가 제빵과정 중 이화적 성분 변화에 미치는 영향 김영호 ;윤성준 pp.265-275

제조법을 달리하여 제조한 오디주의 품질 특성 김미원 ;김애정 pp.276-281

다진 마늘의 첨가 형태에 따른 쿠키의 품질 특성 최덕주 ;신정혜 ;이수정 ;이현지 ;권오천 pp.282-288

검정콩 요구르트 제조에 관한 연구 방병호 ;정은자 pp.289-294

계절에 따른 시판 신선 편이 샐러드 제품의 품질 평가 조순덕 ;윤수진 ;김동만 ;김건희 pp.295-303

슬라이스 치즈 첨가에 의한 재구성 돈육포의 품질 특성 양철영 pp.304-310

오징어 먹물을 첨가한 yellow layer cake 개발에 관한 연구 김미원 ;김애정 ;임영희 ;김명희 pp.311-316

건강 관련 전공 대학생의 지방에 대한 영양 지식과 실천도 원향례 pp.317-324

전주 지역 여대생의 체중 조절에 대한 관심도 및 실행 행태에 관한 연구 노정옥 pp.325-333

실버 소비자의 라이프스타일이 건강기능식품 구매 만족도 및 재 구매 의도에 미치는 영향에 관한 연구 최수일 ;곽종형 pp.334-340

참고문헌 (31건) : 자료제공( 네이버학술정보 )

참고문헌 목록에 대한 테이블로 번호, 참고문헌, 국회도서관 소장유무로 구성되어 있습니다.
번호 참고문헌 국회도서관 소장유무
1 (2001) Conjugated linoleic acid: a review, 미소장
2 Protection of conjugated linoleic acids against 2-amino-3- methylimidazo[4,5-f]quinoline-induced colon carcinogenesis in the F344 rat: a study of inhibitory mechanisms. 네이버 미소장
3 (19-251994) Conjugated linoleic acid and atherosclerosis in rabbits, 미소장
4 (1993) Immune modulation by altered nutrient metabolism nutritional control of immune-induced growth depression, 미소장
5 (1997) Effect of conjugated linoleic acid on body composition in mice, 미소장
6 (2001) Influence of conjugated linoleic acid on body composition and target gene expression in peroxisome proliferator-activated receptor alpha-null mice, 미소장
7 (2001) Effects of conjugated linoleic acid on serum leptin concentration, body fat accumulation, and beta-oxidation of fatty acid in OLETF rat, 미소장
8 (1999) Effects of conjugated linoleic acid(CLA) isomers on lipid levels and peroxisome proliperation in the hamster, 미소장
9 (2001) Conjugated linoleic acid improves feed efficiency, decreases backfat and improves pork quality attributes, 미소장
10 (2004) Conjugated linoleic acid and obesity control: efficacy and mechanisms, 미소장
11 (2004) Influence of dietary conjugated linoleic acid and fat source on body fat and apoptosis in mice, 미소장
12 (2004) The role of stearoyl-Co A desaturase in body weight regulation, 미소장
13 (2004) Structure, function, and dietary regulation of Δ6, Δ5, and Δ9 desaturases, 미소장
14 (1998) Conjugated linoleic acid decrease hepatic stearoyl-Co A desaturase mRNA expression, 미소장
15 (2000) Stearoyl-CoA desaturase 1 gene expression in 3T3-L1 adipocytes, 미소장
16 (2004) Evidence that the anti-obesity effect of conjugated linoleic acid is independent of effects on stearoyl-CoA desaturase1 expression and enzyme activity, 미소장
17 (2007) Conjugated linoleic acid reduce adipose depots without reduction of stearoyl coenzyme A desaturase 1 gene expression, 미소장
18 (2000) Changes in body composition with conjugated linoleic acid, 미소장
19 (1987) Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction, 미소장
20 (1986) Direct trans-esterification of all class of lipid in a one step reaction, 미소장
21 (1999) Evidence that the trans-10, cis-12 isomer of conjugated linoleic acid induces body composition changes in mice, 미소장
22 (2003) Short-term intake of conjugated linoleic acid inhibits lipoprotein lipase and glucose metabolism but does not enhance lipolysis in mouse adipose tissue, 미소장
23 (1999) Conjugated linoleic acid rapidly reduces body fat content in mice without affecting energy intake, 미소장
24 (1998) Effects of conjugated linoleic acid on body fat and energy metabolism in the mouse, 미소장
25 (2000) Conjugated linoleic acid suppresses triglyceride accumulation and induces apoptosis in 3T3-L1 preadipocytes, 미소장
26 (1997) Conjugated linoleic acid modulates hepatic lipid composition in mice, 미소장
27 (2000) Conjugated linoleic acid persistently increases total energy expenditure in AKR/J mice without increasing uncoupling protein gene expression, 미소장
28 (2001) Isomer- specific antidiabetic properties of conjugated linoleic acid. Improved glucose tolerance, skeletal muscle insulin action, and UCP2 gene expression, 미소장
29 (2000) The trans-10, cis-12 isomer of conjugated linoleic acid down regulates stearoyl-CoA desaturase 1 gene expression in 3T3-L1 adipocytes, 미소장
30 (2001) Regulation of stearoyl-CoA desaturase activity by the trans-10, cis-12 isomer of conjugated linoleic acid in HepG2 cells, 미소장
31 (2002) Conjugated linoleic acid differentially modifies fatty acid composition in subcellular fractions of muscle and adipose tissue but not adiposity of postweaning pigs, 미소장