권호기사보기
기사명 | 저자명 | 페이지 | 원문 | 기사목차 |
---|
대표형(전거형, Authority) | 생물정보 | 이형(異形, Variant) | 소속 | 직위 | 직업 | 활동분야 | 주기 | 서지 | |
---|---|---|---|---|---|---|---|---|---|
연구/단체명을 입력해주세요. |
|
|
|
|
|
* 주제를 선택하시면 검색 상세로 이동합니다.
Recent research has revealed that hydrolyzed collagen peptides have beneficial effects in various diseases such
as osteoarthritis and human rheumatoid arthritis and also play a protective role in skin by improving the activity of
antioxidants. In this study, we investigated the effects of a novel mixture (AP-CPM01) containing collagen peptides and
elastin peptides on photoaged hairless mice skin both in vivo and in vitro. To evaluate the effects of AP-CPM01 on UVBinduced
skin wrinkle formation in vivo, the hairless mice were exposed to UVB irradiation and orally administered the
AP-CPM01 at 333 mg/kg per day for 10 weeks. The effects on skin appearance and epidermal thickness were measured
using bioengineering and histochemical methods. In addition, the influence of AP-CPM01 on collagen metabolism in
human skin fibroblasts was also investigated. The skin of mice in the AP-CPM01 treated group had better appearance and
less wrinkling than that of mice in the control group. In the human fibroblast cells, the amount of de novo procollagen
synthesis was increased after AP-CPM01 treatment, reflecting that AP-CPM01 can induce de novo procollagen synthesis
and reduce UVB-induced skin wrinkle formation. These results suggest that AP-CPM01 is a potent candidate for antiphotoaging
functions.*표시는 필수 입력사항입니다.
*전화번호 | ※ '-' 없이 휴대폰번호를 입력하세요 |
---|
기사명 | 저자명 | 페이지 | 원문 | 기사목차 |
---|
번호 | 발행일자 | 권호명 | 제본정보 | 자료실 | 원문 | 신청 페이지 |
---|
도서위치안내: 정기간행물실(524호) / 서가번호: 국내13
2021년 이전 정기간행물은 온라인 신청(원문 구축 자료는 원문 이용)
우편복사 목록담기를 완료하였습니다.
*표시는 필수 입력사항입니다.
저장 되었습니다.