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The world’s first face transplantation was performed in France, in 2005. Since then, 21 cases of face transplantation have been performed. Face transplantation is one of the most prominent part of composite tissue allotransplantation (CTA) along with hand transplantation. Since these fields are not deal with life-saving organs, there are many arguments about immunosuppression therapy. Recent paradigm of face transplantation shows that surgical ranges are expanded from partial face transplantation to full face transplantation. Most immunosuppression protocols are triple therapy, which consists of tacrolimus (FK-506), mycophenolate mofetil and prednisolone. Anatomical researches, immunosuppression, and immunotolerance take great parts in the researches of CTA. The medical fields directly related to face transplantation are microsurgery, immunology, and transplantation. Nowadays, each field is performed widely. Therefore people, even medical teams think face transplantation could be easily realized, sooner or later. But there are lots of things that should be prepared for not only practice and immunosuppression therapy but also for the cooperation with relevant fields. That’s the reason why only 21 cases of face transplantation have been done, while more than 70 cases of hand transplantation have been done in the past years. Especially in Korea, brain death patients are not enough even for organ transplantation and furthermore there are some troubles in taking part in the society of transplantation. Face transplantation has lots of problems concerning variable medical fields, administration, society, ethics, and laws. Therefore, for the realization of face transplantation in Korea, not only medical skills but also political powers are needed.

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참고문헌 (43건) : 자료제공( 네이버학술정보 )

참고문헌 목록에 대한 테이블로 번호, 참고문헌, 국회도서관 소장유무로 구성되어 있습니다.
번호 참고문헌 국회도서관 소장유무
1 Facial transplantation 네이버 미소장
2 Donor operation for face transplantation. 네이버 미소장
3 Ethical considerations in human facial tissue allotransplantation. 네이버 미소장
4 Byeon JH, Kim MC, Lee HJ, Lim P: Effect of cyclosporin-A on the allotransplantation of skin and free flap in rats. J Korean Soc Plast Reconstr Surg 26: 284, 1989 미소장
5 Baek RM, Kim CW: Experimental study on composite tissue allotransplantation in rats. J Korean Soc Plast Reconstr Surg 16: 465, 1989 미소장
6 The Effect of FK-506 and Cyclosporine A on Survival of Skin Allograft in Mice 네이버 미소장
7 Woo SH: The concept and current trends of composite tissue allotransplantation. J Korean Soc Reconstr Hand Surg 6: 84, 2001 미소장
8 Investigation of Risk Acceptance and Expectations in Hand and Foot Allotransplantations 소장
9 Evaluation of Reliability and Validity of the Louisville Instrument for Transplantation(LIFT) in Korean Population 소장
10 A New Facial Composite Flap Model(Panorama Facial Flap) with Sensory and Motor Nerve from Cadaver Study for Facial Transplantation 소장
11 Experimental Hind Limb & Inguinal-Femur Osteocutaneous Flap Model in Rats for Composite Tissue Transplantation 소장
12 FACE TRANSPLANTATION OUTCOMES: FEASIBILITY REPRODUCIBILITY AND EFFICACY 네이버 미소장
13 Korea Ministry of Government Legistation: Organs, etc. Transplant Act. 2011. http://www.law.go.kr/lsSc.do?menuId=0&p1=&subMenu =1&nwYn=1&query=%EC%9E%A5%EA%B8%B0%EB%93%B1+% EC%9D%B4%EC%8B%9D%EC%97%90+%EA%B4%80%ED%95% 9C+%EB%B2%95%EB%A5%A0&x=28&y=9#liBgcolor0. accessed August 4, 2011 미소장
14 Composite Tissue Allotransplantation and Reconstructive Surgery 네이버 미소장
15 Lantieri L, Hivelin M, Audard V, Benjoar MD, Meningaud JP, Bellivier F, Ortonne N, Lefaucheur JP, Gilton A, Suberbielle C, Marty J, Lang P, Grimbert P: Feasibility, reproducibility, risks and benefits of face transplantation: a prospective study of outcomes. Am J Transplant 11: 367, 2011 미소장
16 Outcomes 18 months after the first human partial face transplantation. 네이버 미소장
17 Committee for New Health Technology Assessment: Small bowel transplantation new health technology assessment report (H31- 2009-21). 2011. http://nhta.or.kr/nHTA/04_info/01_report_view.jsp? t=20120924203359364&boardNo=1&cpage=1&seq=1151. accessed July 26, 2011 미소장
18 Experimental facial transplantation surgery. 네이버 미소장
19 Hettiaratchy S, Randolph MA, Petit F, Lee WP, Butler PE: Composite tissue allotransplantation--a new era in plastic surgery? Br J Plast Surg 57: 381, 2004 미소장
20 Ravindra KV, Wu S, McKinney M, Xu H, Ildstad ST: Composite tissue allotransplantation: current challenges. Transplant Proc 41: 3519, 2009 미소장
21 Clinical considerations in face transplantation. 네이버 미소장
22 Three Patients with Full Facial Transplantation 네이버 미소장
23 Brown EN, Dorafshar AH, Bojovic B, Christy MR, Borsuk DE, Kelley TN, Shaffer CK, Rodriguez ED: Total face, double jaw, and tongue transplant simulation: a cadaveric study employing computer-assisted techniques. Plast Reconstr Surg 130: 815, 2012 미소장
24 Facial composite tissue allograft. 네이버 미소장
25 Siemionow MZ, Papay F, Djohan R, Bernard S, Gordon CR, Alam D, Hendrickson M, Lohman R, Eghtesad B, Fung J: First U.S. near-total human face transplantation: a paradigm shift for massive complex injuries. Plast Reconstr Surg 125: 111, 2010 미소장
26 Novel surgical technique for full face transplantation. 네이버 미소장
27 Meningaud JP, Benjoar MD, Hivelin M, Hermeziu O, Toure G, Lantieri L: Procurement of total human face graft for allotransplantation: a preclinical study and the first clinical case. Plast Reconstr Surg 126: 1181, 2010 미소장
28 Full Face Transplant 네이버 미소장
29 Relative antigenicity of components of a vascularized limb allograft. 네이버 미소장
30 Advances in composite tissue allograft transplantation as related to the hand and upper extremity 네이버 미소장
31 Whitaker IS, Duggan EM, Alloway RR, Brown C, McGuire S, Woodle ES, Hsiao EC, Maldonado C, Banis JC Jr, Barker JH: Composite tissue allotransplantation: a review of relevant immunological issues for plastic surgeons. J Plast Reconstr Aesthet Surg 61: 481, 2008 미소장
32 Jurewicz WA: Tacrolimus versus cyclosporin immunosuppression: long-term outcome in renal transplantation. Nephrol Dial Transplant 18 Suppl 1: i7, 2003 미소장
33 Chimerism and bone marrow based therapies in transplantation 네이버 미소장
34 TRANSPLANTATION 네이버 미소장
35 Daily topical tacrolimus therapy prevents skin rejection in a rodent hind limb allograft model. 네이버 미소장
36 Mouse hind limb transplantation: a new composite tissue allotransplantation model using nonsuture supermicrosurgery. 네이버 미소장
37 Prolongation of composite tissue allotransplant survival by treatment with bone marrow mesenchymal stem cells is correlated with T-cell regulation in a swine hind-limb model. 네이버 미소장
38 English K, Ma- hon BP: Allogeneic mesenchymal stem cells: agents of immune modulation. J Cell Biochem 112: 1963, 2011 미소장
39 Committee for New Health Technology Assessment: Hand transplantation new health technology assessment report (H31-2010-36). 2010. http://nhta.or.kr/nHTA/04_info/01_report_view.jsp?t=20120924203 359364&boardNo=1&cpage=1&seq=1215. accessed June 27, 2011 미소장
40 Korea Network for Organ Sharing: Transplantation statistical data.2011. http://www.konos.go.kr/konosis/sub5/sub05_pop.jsp?tabno=2&pid=57. accessed September 25, 2012 미소장
41 Siemionow M: Face transplantation: a leading surgeon's perspective. Transplant Proc 43: 2850, 2011 미소장
42 Institutional review board-based recommendations for medical institutions pursuing protocol approval for facial transplantation. 네이버 미소장
43 Siemionow MZ, Rampazzo A, Gharb BB: Addressing religious and cultural differences in views on transplantation, including composite tissue allotransplantation. Ann Plast Surg 66: 410, 2011 미소장

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