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Purpose: Limited data are available on the role of percutaneous cardiopulmonary support (PCPS) for the treatment of acute myocardial infarction (AMI) patients with cardiogenic shock. We investigated the clinical outcomes and predictors of in-hospitalmortality after PCPS in patients with AMI complicated by severe refractory cardiogenicshock. Materials and Methods: From January 2004 to December 2011, we analyzed data from 96 consecutive AMI patients with cardiogenic shock assisted by a PCPS system. The primary outcome was in-hospital mortality. The predictors of in-hospital mortality were determined by a Cox proportional-hazards model. Results:In-hospital mortality occurred in 51 (53.1%) patients and 58 (60.4%) patients were able to be weaned from PCPS. Cardiopulmonary resuscitation (CPR) was performedin 61 (63.5%) patients before PCPS initiation. On multivariate analysis, age ≥67 years [adjusted hazard ratio (HR), 4.74; 95% confidence interval (CI), 2.27--9.93; p<0.001], CPR (adjusted HR, 2.32; 95% CI, 1.11--4.85; p=0.03), lactate clearancefor 48 hours <70% (adjusted HR, 2.50; 95% CI, 1.04--6.05; p=0.041), and unsuccessfulrevascularization (adjusted HR, 3.57; 95% CI, 1.85--6.90; p=0.002) were independent predictors of in-hospital mortality after PCPS in patients with AMI complicated by cardiogenic shock. Conclusion: In spite of PCPS management, AMI patients complicated by severe refractory cardiogenic shock demonstrated high mortality. Older age, CPR, lower lactate clearance for 48 hours, and unsuccessful revascularizationwere independent predictors of in-hospital mortality.

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참고문헌 (22건) : 자료제공( 네이버학술정보 )

참고문헌 목록에 대한 테이블로 번호, 참고문헌, 국회도서관 소장유무로 구성되어 있습니다.
번호 참고문헌 국회도서관 소장유무
1 Early Revascularization in Acute Myocardial Infarction Complicated by Cardiogenic Shock 네이버 미소장
2 Revascularization, stenting, and outcomes of patients with acute myocardial infarction complicated by cardiogenic shock 네이버 미소장
3 Clinical review: mechanical circulatory support for cardiogenic shock complicating acute myocardial infarction. 네이버 미소장
4 Outcome of Patients With Profound Cardiogenic Shock After Cardiopulmonary Resuscitation and Prompt Extracorporeal Membrane Oxygenation Support 네이버 미소장
5 Extracorporeal cardiopulmonary resuscitation in patients with inhospital cardiac arrest: A comparison with conventional cardiopulmonary resuscitation. 네이버 미소장
6 Goldberg RJ, Spencer FA, Gore JM, Lessard D, Yarzebski J. Thirty-year trends (1975 to 2005) in the magnitude of, management of, and hospital death rates associated with cardiogenic shock in patients with acute myocardial infarction: a population-based perspective. Circulation 2009;119:1211-9. 미소장
7 Trends in management and outcomes of patients with acute myocardial infarction complicated by cardiogenic shock. 네이버 미소장
8 Intraaortic balloon support for myocardial infarction with cardiogenic shock. 네이버 미소장
9 Sjauw KD, Engström AE, Vis MM, van der Schaaf RJ, Baan J Jr, Koch KT, et al. A systematic review and meta-analysis of intra-aortic balloon pump therapy in ST-elevation myocardial infarction: should we change the guidelines? Eur Heart J 2009;30:459-68. 미소장
10 Cheng JM, den Uil CA, Hoeks SE, van der Ent M, Jewbali LS, van Domburg RT, et al. Percutaneous left ventricular assist devices vs. intra-aortic balloon pump counterpulsation for treatment of cardiogenic shock: a meta-analysis of controlled trials. Eur Heart J 2009;30:2102-8. 미소장
11 The Percutaneous Ventricular Assist Device in Severe Refractory Cardiogenic Shock 네이버 미소장
12 Improved Survival After Cardiac Arrest Using Emergent Autopriming Percutaneous Cardiopulmonary Support 네이버 미소장
13 Efficacy of veno-arterial extracorporeal membrane oxygenation in acute myocardial infarction with cardiogenic shock 네이버 미소장
14 Predictive factors for successful weaning from percutaneous cardiopulmonary support in patients with cardiogenic shock complicating acute myocardial infarction. 네이버 미소장
15 Extracorporeal membrane oxygenation-assisted primary percutaneous coronary intervention may improve survival of patients with acute myocardial infarction complicated by profound cardiogenic shock 네이버 미소장
16 Extracorporeal Life Support for Cardiogenic Shock or Cardiac Arrest Due to Acute Coronary Syndrome 네이버 미소장
17 Should we emergently revascularize occluded coronaries for cardiac arrest?: rapid-response extracorporeal membrane oxygenation and intra-arrest percutaneous coronary intervention. 네이버 미소장
18 Cardiac resuscitation with percutaneous cardiopulmonary support 네이버 미소장
19 Using extracorporeal membrane oxygenation to rescue acute myocardial infarction with cardiopulmonary collapse: The impact of early coronary revascularization 네이버 미소장
20 Early lactate clearance is associated with improved outcome in severe sepsis and septic shock 네이버 미소장
21 Lactate clearance in cardiogenic shock following ST elevation myocardial infarction: a pilot study. 네이버 미소장
22 Outcome of in-hospital adult cardiopulmonary resuscitation assisted with portable auto-priming percutaneous cardiopulmonary support. 네이버 미소장

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