표제지
목차 3
서 론 3
대상 및 방법 5
결 과 9
고 찰 28
요 약 32
참고문헌 34
영문초록 39
표목차 14
Table 1. Primer sequences 14
Table 2. Characteristics of the study population 15
Table 3. Genotype frequencies of XPC polymorphisms in lung cancer and control 16
Table 4. Adjusteda odds ratios for lung cancer associated with XPC genotypes 17
Table 5. Linkage disequ ilibrium between XPC -449G]C and Val499Ala polymorphisms in 320 controls 18
Table 6. Linkage disequilibrium between XPC -449G]C and PAT polymorphisms in 320 controls 19
Table 7. Linkage disequilibrium between XPC -449G]C and Lys939Gln polymorphisms in 319 controls 20
Table 8. Linkage disequilibrium between XPC Val499Ala and PAT polymorphisms in 322 controls 21
Table 9. Linkage disequilibrium between XPC Val499Ala and Lys939Gln polymorphisms in 320 controls 22
Table 10. Linkage disequilibrium between XPC PAT an d Ly s939Gln polymorphisms in 320 controls 23
Table 11. Analysis of XPC haplotype frequencies, adjusteda odds ratios for lung cancer 24
그림목차 25
Figure 1. Representative figure of XPC -499G]C genotypes 25
Figure 2. Representative figure of XPC Val499Ala genotypes 25
Figure 3. Representative figure of XPC poly (AT) insertion/deletion genotypes 26
Figure 4. Representative figure of XPC Ly s939Gln genotypes 26
Figure 5. Transcriptional activities 27