Title Page
Contents
I. Introduction 6
II. Materials and Methods 9
1. Study subjects 9
2. Analysis of pbNK cell fraction 9
3. Analysis of pbNK cell cytotoxicity 10
4. Evaluation of uterine blood flow 11
5. LMWH treatment 12
6. Outcome measures 12
7. Statistical analysis 12
III. Results 14
IV. Discussion 16
V. References 19
VI. 국문초록 22
Table 1. Clinical characteristics of study groups. 29
Table 2. Comparison of uterine radial artery resistance index between study groups. 30
Table 3. Mean uterine radial artery resistance index before and after LMWH treatment. 31
Table 4. Comparison of pregnancy outcomes between controls and patients with RAS treated with LMWH. 31
Figure 1. Flowchart and breakdown of study subjects. 24
Figure 2. Measurement of uterine blood flow by transvaginal Doppler ultrasonogram. 25
Figure 3. Comparison of mean uterine radial artery resistance index between groups. 26
Figure 4. Correlation of uterine radial artery resistance index and pbNK cell fractions(n=33) 27
Figure 5. Correlations between uterine radial artery resistance index and pbNK cell fractions in normal (n=13) and elevated pbNK cell fractions (n=20). 27
Figure 6. Mean uterine radial artery resistance index before and after LMWH treatment. 28