Title Page
Contents
I. Introduction 7
II. Methods and Materials 9
Patients 9
Clinical features of the AIS patients 9
CT scanning 9
CT findings and the pathologic features of AIS 10
Statistical analysis 11
III. Results 12
Clinical features of AIS patients 12
CT findings of AIS 14
Comparison of CT features between groups A and B 17
Pathologic findings of AIS 19
Pathologic comparisons between groups A and B 20
IV. Discussions 27
V. References 33
VI. Abstracts 35
Table. 1. Patient demographics 13
Table. 2. Comparisons of patient demographics between groups A and B 14
Table. 3. Nodule location and surgery method 15
Table. 4. Morphology of nodules in thin-section CT 16
Table. 5. Comparison of interval change among three nodule types 16
Table. 6. Comparison of CT morphology between groups A and B 18
Table. 7. Comparison of nodule location and surgery method between groups A and B 19
Fig. 1. Typical appearance of the three GGN patterns, three nodule shapes and two margins. 8
Fig. 2. Reversed halo sign of a GGN in the right upper lobe confirmed as an adenocarcinoma in situ in a 74-year-old woman. 20
Fig. 3. Reversed halo sign of GGN in the left upper lobe confirmed as an adenocarcinoma in situ in a 72-year-old woman. 22
Fig. 4. Reversed halo sign of GGN in the right lower lobe confirmed as an adenocarcinoma in situ in a 51-year-old woman. 23
Fig. 5. GGN in the right lower lobe confirmed as an adenocarcinoma in situ in a 74-year-old woman with a history of colon cancer and thyroid cancer. 24
Fig. 6. GGN in the left lower lobe confirmed as an adenocarcinoma in situ in a 36-year-old man. 25
Fig. 7. Part-solid GGN in the right upper lobe confirmed as mucinous adenocarcinoma in situ in a 65-year-old man. 26