Title Page
Contents
국문초록 8
ABSTRACT 10
I. Introduction 12
II. Objectives 15
III. Materials and Methods 16
1. Materials 16
2. Methods 18
IV. Results 20
1) The incidence of central precocious puberty 20
2) Age-specific incidence of central precocious puberty 24
3) The prevalence of CPP 30
V. Discussion 34
VI. Conclusion 42
References 43
Table 1. The annual incidence (95% confidence interval) of central precocious puberty per calendar year 22
Table 2. The annual incidence of central precocious puberty according to the sex and age at diagnosis 26
Table 3. The estimated change of central precocious puberty incidence rates per year (IRR and 95% CI) between 2008 and... 28
Table 4. The prevalence (95% confidence interval) of central precocious puberty according to the sex, calendar year, and two diagnostic age limits 32
Fig 1. The annual incidence of central precocious puberty. 21
Fig 2. The annual incidence of central precocious puberty according to sex and age at diagnosis. 27
Fig 3. Age distribution of central precocious puberty patients according to sex and calendar year. 29
Fig 4. The annual prevalence of central precocious puberty according to sex, calendar year, and two diagnostic age limits. 31