Title Page
Contents
ABSTRACT 8
Ⅰ. Introduction 9
Ⅱ. Materials and Methods 12
2.1. Ethical Statement 12
2.2. Sample Collection 12
2.3. Patient Information 12
2.4. Histopathological Evaluation 13
2.5. Immunohistochemistry 13
Ⅲ. Results 16
3.1. Histopathological evaluation and Immunohistochemistry 16
3.1.1. Nodular Hyperplasia Nodular hyperplasia was dia 18
3.1.2. Hematoma 20
3.1.3. Splenic Hemangiosarcoma 22
3.1.4. Splenic Lymphoma 24
3.1.5. Stromal Sarcomas 27
3.1.6. Myelolipoma 29
3.1.7. Mast Cell Tumor 31
Ⅳ. Discussion 33
Ⅴ. Conclusion 38
References 39
Abstract (in Korean) 43
〈Table 1〉 Primary antibodies and immunohistochemical staining protocols used in this study 15
〈Table 2〉 Histopathological diagnoses of 137 canine splenic tissues in this study 17
〈Figure 1〉 Nodular hyperplasia in the spleen of a dog. 19
〈Figure 2〉 Hematoma in the spleen of a dog. 21
〈Figure 3〉 Splenic hemangiosarcoma in the spleen of a dog. 23
〈Figure 4〉 Splenic lymphoma in the spleen of dogs. 25
〈Figure 5〉 Stromal sarcomas in the spleens of dogs. 28
〈Figure 6〉 Myelolipoma in the spleen of a dog. 30
〈Figure 7〉 Splenic mast cell tumor in the spleen of a dog. 32