Title Page
Contents
국문초록 8
ABSTRACT 10
1. Introduction 12
2. Objective 15
3. Methods 16
3.1. Participants 16
3.2. Acquisition of DTI 17
3.3. Calculation of the DTI-ALPS index 17
3.4. Statistical analysis 18
4. Results 19
4.1. Demographic and clinical characteristics of patients with focal epilepsy and healthy controls 19
4.2. Differences in the DTI-ALPS index between patients with focal epilepsy and healthy controls and between poor and good ASM responders 19
4.3. Correlation analysis between DTI-ALPS index and clinical characteristics in patients with focal epilepsy 19
5. Discussion 21
6. Conclusion 25
References 26
Table 1. Demographic and clinical characteristics in patients with focal epilepsy and healthy controls 30
Table 2. The differences in diffusivities and DTI-ALPS index values between patients with focal epilepsy and healthy controls, and between poor and good ASM responders 31
Figure 1. Process for calculation of the DTI-ALPS index in this study 33
Figure 2. Differences in the DTI-ALPS index between patients with focal epilepsy and healthy controls and between poor and good ASM responders 34
Figure 3. Correlation analysis between the DTI-ALPS index and clinical characteristics in patients with focal epilepsy 35