Title Page
Contents
ABSTRACT 10
1. Introduction 12
2. Materials and Methods 16
2.1. Data collection 16
2.2. Clinical status analysis 18
2.2.1. Signalment and clinical examination 18
2.2.2. Diagnosis of FIP 19
2.2.3. Radiographic and ultrasonographic analysis 21
2.2.4. Treatment and follow-up 39
2.3. Statistical analysis 40
3. Results 42
3.1. Signalment 42
3.2. Clinical presentation 46
3.2.1. Non-effusive and effusive form 46
3.2.2. Presenting signs 47
3.2.3. Ocular signs 48
3.2.4. Neurological signs 49
3.3. Diagnostic testing 52
3.3.1. Hematology and serum biochemistry 52
3.3.2. Effusion analysis 57
3.4. Antiviral treatment 59
3.5. Imaging features 60
3.5.1. Radiographic analysis 60
3.5.2. Ultrasonographic analysis 62
3.5.3. Hyperbilirubinemia and image findings 75
3.6. Outcome 77
3.6.1. Clinical response to antiviral treatment 77
3.6.2. Non survivors 80
4. Discussion 82
5. Conclusion 94
References 95
Abstract (in Korean) 101
Table 1. Radiographic image variables of abdomen and thorax features analysis 24
Table 2. Ultrasonographic image variables of abdominal cavity features analysis 25
Table 3. Ultrasonographic image variables of hepatobiliary and pancreatic features analysis 26
Table 4. Ultrasonographic image variables of kidney features analysis 27
Table 5. Ultrasonographic image variables of gastrointestinal features analysis 28
Table 6. Ultrasonographic image variables of spleen and lymph node features analysis 29
Table 7. Age, sex, body weight and environment of the presumptively diagnosed FIP cats 44
Table 8. Breeds of the presumptively diagnosed FIP cats 45
Table 9. Clinical signs of 80 cats with presumptive FIP at the time of diagnosis 50
Table 10. Hematological and biochemical findings in 80 cats with presumptive FIP at the time of diagnosis 53
Table 11. Effusion analysis of the presumptively diagnosed FIP cats 58
Table 12. Radiographic image variables of abdomen and thorax features 61
Table 13. Ultrasonographic image variables of abdominal cavity features 67
Table 14. Ultrasonographic image variables of hepatobiliary and pancreatic features 68
Table 15. Ultrasonographic image variables of kidney features 69
Table 16. Ultrasonographic image variables of gastrointestinal features 71
Table 17. Ultrasonographic image variables of spleen and lymph node features 73
Table 18. Significant correlations in presumptively diagnosed FIP patients between hyperbilirubinemia and ultrasonographic findings of extensive peritoneal effusion in all four AFAST views and normal-sized mesenteric lymph node 76
Table 19. Changes to body weight after treatment and number of days until clinical signs resolved in follow-up course of cats who started antiviral treatment 79
Figure 1. Representative right lateral abdominal radiographic images of serosal detail loss classified based on the severity. 30
Figure 2. Representative ventrodorsal thoracic radiographic images of pleural effusion classified based on the severity. 31
Figure 3. Representative right lateral thoracic radiographic images of patchy alveolar pattern and pulmonary nodule. 32
Figure 4. Representative ultrasonographic images of peritoneal effusion present in four different AFAST locations on the abdomen utilized for classifying the... 33
Figure 5. Representative ultrasonographic images of hepatobiliary and pancreatic features. 34
Figure 6. Representative ultrasonographic images of kidney features. 35
Figure 7. Representative ultrasonographic images of gastrointestinal features. 36
Figure 8. Representative ultrasonographic images of spleen features. 37
Figure 9. Representative ultrasonographic images of lymph node features. 38
Figure 10. Ultrasonographic images of the marked thickening of the ileocecocolic region in sagittal (top of A and B) and transverse (bottom of A and B, C) views. 72
Figure 11. Box and whisker plot depicting enlarged mesenteric lymph node size (mm) of 46 cats with presumptive FIP at the time of diagnosis. 74
Figure 12. Changes in imaging findings in response to antiviral treatment. 81