Title Page
Contents
ABSTRACT 9
Ⅰ. Introduction 11
Ⅱ. Materials and Methods 14
2.1. Animals 14
2.2. Data collection 14
2.3. Blood examination 16
2.4. Imaging diagnostic examination 16
2.5. Mastectomy 17
2.6. Statistical analysis 18
Ⅲ. Results 20
3.1. Age distribution 20
3.2. Gender distribution 20
3.3. Breed distribution. 23
3.4. Body condition score distribution 23
3.5. Tumor location, number and maximal diameter 26
3.6. Distribution of TNM stages 30
3.7. Prevalence of underlying diseases 30
3.8. Types of surgeries conducted 33
3.9. Reason for refusal of surgery 35
3.10. Correlation between tumor maximum diameter and C-reactive protein 37
3.11. Correlation between body condition score, C-reactive protein, and D-dimer 37
3.12. Correlation between body weight and tumor maximum diameter 41
Ⅳ. Discussion 43
Ⅴ. Conclusion 48
Reference 49
ABSTRACT (in Korean) 53
Table 1. Comparison of age distribution between dogs that underwent surgery and those that did not 21
Table 2. Comparison of gender distribution between dogs that underwent surgery and those that did not 22
Table 3. Comparison of breed distribution between dogs that underwent surgery and those that did not 24
Table 4. Distribution of body condition score between dogs that underwent surgery and those that did not 25
Table 5. Distribution of maximum tumor diameter between dogs that underwent surgery and those that did not 27
Table 6. Distribution of tumor count between dogs that underwent surgery and those that did not 28
Table 7. Distribution of tumor locations between dogs that underwent surgery and those that did not 29
Table 8. Distribution of TNM stage between dogs that underwent surgery and those that did not 31
Table 9. Distribution of kidney disease, heart disease, and presence of other tumors in dogs that underwent surgery compared to those that did not 32
Table 10. Types and frequency of mammary gland surgeries performed on dogs that underwent surgery 34
Table 11. Distribution of reasons for clinic visits between dogs that underwent surgery and those that did not and reasons for refusal of surgery 36
Table 12. Analysis of the relationship between maximum tumor diameter and C-reactive protein 38
Table 13. Correlation between body condition score, D-dimer, and C-reactive protein 40
Table 14. Relationship between body weight and maximum tumor diameter 42
Figure 1. Analysis of the relationship between C-reactive protein levels and maximum tumor diameter 39