Contents
Pharmacokinetic and hydrolysis study of new celecoxib prodrug / 민혜란 ; 김희두 ; 오승열 1
Abstract 1
Introduction 1
Materials and methods 2
1. Materials 2
2. HPLC Instrumentation and Chromatographic Conditions 3
3. solubility Study 3
4. Animals 3
5. In Vitro Hydrolysis Study 3
6. Single Dose Pharmacokinetic Experiments 4
7. Assay Procedure 4
8. Pharmacokinetic Calculations 4
9. Preparations of Stock Solutions, Calibration Standards 5
Result and discussion 5
Acknowledgement 7
Reference 7