Objectives : The purpose of this study is to observe the effects of RUBI FRUCTUS phamacopuncture infusion solution at KI_10_ on osteoporotic Rats Induced by ovariectomy.
Methods : The author performed several experimental items to analyze cytotoxic, osteoporosis evaluation, change of ALP, creatinine, Ca, P, osteocalcin, Ca/P ratio and histological change of serum and tibia.
Results :
1. Creatinine and phosphorus in serum was decreased significantly in RF-HA than control group.
2. Calcium and phosphorus in tibia was increased significantly in RF-HA than control group.
3. Osteoclast like cell in tibia was increased significantly in control group, decreased significantly in RF-HA.
4. In the histological study in tibia, TBT was significantly increased, GPL was significantly decreased in the RF-HA than control group.
Conclusions : This study suggested that RF-HA at KI10 has significant effect on osteoporosis.