Intracranial involvement in multiple myeloma patients takes up around 1%, and isusually known to be present in the parietal bone or skull base in cases of skull vaultinvolvement, while it presents in the dura and parenchyma in cases of intracranialinvolvement. Primary pachymeningeal invasion is even rarer with extremely rapidprogression and very poor prognosis. It is our intent to report a case in which wehad to differentiate multiple myeloma with other metastatic tumors, lymphoma, andleukemia with intracranial involvement. Our patient showed an osteolytic lesion ofthe skull with dural involvement and subdural mass formations.