Wernicke’s encephalopathy (WE) is an acute neurological disorder resulting fromthiamine deficiency. Early diagnosis and treatment of WE is important to avoidpersistent brain damage. Although histopathologic examination usually demonstratespin-point hemorrhages in affected brain parenchyma, secondary hemorrhage is arare but serious complication of WE. We experienced a rare case of intracranialhemorrhage related to WE in a 56-year-old male patient with malnourishment.