Objectives: Aluminum is well known as a potent neurotoxicant. There are many reports that aluminum can betoxic to humans and to animals. However, there are only few studies on the assessment of aluminum exposureamong humans in Korea. Therefore, the aim of this study was to evaluate current aluminum concentrationsamong the adult population in regions of Korea.
Methods: We selected 439 adults aged 20-89 years from the Busan-Ulsan-Gyeongnam region and certain othersites. Blood aluminum concentrations were analyzed using inductively-coupled plasma mass spectrometry (ICP/MS). The geometric means (GM) and 95% confidence intervals (CI) of aluminum concentrations werecalculated, and we also confirmed the proportion of excess of the aluminum reference value.
Results: Total GM (95% CI) of aluminum levels was 14.26 (13.43-15.14) ppb. Levels among males (15.58[14.09-17.22] ppb) were higher compared to among females (13.51 [12.54-14.55] ppb), and levels increased withsubject age from 40 years and over. Three point one nine percent of the subjects exceed the reference value of50 ppb. Lastly, aluminum concentration has a log-normal distribution with lnN (x; 2.89, 0.642), x>0.
Conclusion: In the present study, we evaluated the distribution of blood aluminum concentrations among the normalpopulation in Korea, and we found some adults exceeding the reference levels. However, in order to compare theresults with other studies, an extended study including measurement of serum aluminum level is required. In addition,further research on various population groups, including occupational exposure of workers, is required.Objectives: Aluminum is well known as a potent neurotoxicant. There are many reports that aluminum can betoxic to humans and to animals. However, there are only few studies on the assessment of aluminum exposureamong humans in Korea. Therefore, the aim of this study was to evaluate current aluminum concentrationsamong the adult population in regions of Korea.
Conclusion: In the present study, we evaluated the distribution of blood aluminum concentrations among the normalpopulation in Korea, and we found some adults exceeding the reference levels. However, in order to compare theresults with other studies, an extended study including measurement of serum aluminum level is required. In addition,further research on various population groups, including occupational exposure of workers, is required.