Contents
Nano-biomarker-based surface-enhanced raman spectroscopy for selective diagnosis of gallbladder and liver injury / Sanghwa Lee ; Eunyoung Tak ; Yu Jeong Cho ; Jiye Kim ; Jooyoung Lee ; Ryunjin Lee ; Kwanhee Lee ; Minsung Kwon ; Young-In Yoon ; Sung-Gyu Lee ; Jung-Man Namgoong ; Jun Ki Kim 1
Abstract 1
1. Introduction 1
2. Materials and Methods 2
2.1. Bile Duct Ligation 2
2.2. Thermal Cauterization Treatment 2
2.3. Blood Sampling and Laboratory Tests 3
2.4. Western Blot 3
2.5. Histology Analysis 3
2.6. Statistical Analyses 3
2.7. Surface-Enhanced Raman Sensing Chip Preparation 4
2.8. Raman Measurements and Principal Component Analysis 4
3. Results and Discussion 4
3.1. Comparison of the Effects of Bile Duct Ligation and Gallbladder Cauterization on Liver Damage 4
3.2. Assessment of Gallbladder Damage Via Histopathology 4
3.3. Signal Analysis Through Raman Spectra 5
3.4. Principal Component Statistical Analysis of Results 7
4. Conclusion 8
References 8