Contents 1
Magnetic nanochain-based smart drug delivery system with remote tunable drug release by a magnetic field / Byunghoon Kang ; Moo-Kwang Shin ; Seungmin Han ; Ilyoung Oh ; Eunjung Kim ; Joseph Park ; Hye Young Son ; Taejoon Kang ; Juyeon Jung ; Yong-Min Huh ; Seungjoo Haam ; Eun-Kyung Lim 1
Abstract 1
1. Introduction 2
2. Results and Discussion 2
3. Conclusion 7
4. Materials and Methods 7
4.1. Materials 7
4.2. Preparation of Magnetic(Fe₃O₄) Nanoclusters(MNCs) 8
4.3. Synthesis of Magnetic Nanochains(MNs) 8
4.4. Synthesis of MSMNs 8
4.5. Simulation of Motions of MSMNs Under a Rotating MF 8
4.6. Magnetic Torque 8
4.7. Fluid Viscous Torque 8
4.8. Governing Eq. 8
4.9. Solutions 9
4.10. Cytotoxicity Assay 9
4.11. Preparation of Drug-Loaded MSMN(DOX-MSMNs) 9
4.12. Drug Release Profile of DOX-MSMN Under External Rotating MF Control 9
4.13. Preparation of Ap-DOX-MSMNs 10
4.14. In Vitro Therapeutic Efficacy of Ap-DOX-MSMNs Under External Rotating MF Control 10
References 10