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The study was conducted to determine whether oak wood vinegar extract influences blood alcohol concentration and hangover syndrome in healthy volunteers. 2% wood vinegar extract was effective to inhibit increase of blood alcohol concentration after alcohol intake and showed significantly different (P<0.1) compared to placebo. By result of questionnaire of volunteers, wood vinegar extract showed effects improving hangover syndrome. In comparative study about blood alcohol concentration and hangover syndrome of wood vinegar extract and other extract that hangover improvement effect was reported, average maximum blood alcohol concentration was lowered in those taking wood vinegar extract than those taking other extract. At drinking completion 210minutes (T210), blood alcohol concentration of those taking wood vinegar extract was the lowest by 0.063% compared with other extract but was not significantly different between in those taking wood vinegar extract and in those taking other extract. However, wood vinegar extract's experimental group was the highest by 0.462 in decrement rate of blood alcohol concentration and, when did P<0.1 by significance level, indicated difference that mean statistically compared to placebo group uniquely. At those taking wood vinegar extract, the improvement rate and the aggravation rate of hangover syndrome was each 87%, 2%. Thus it was concluded that wood vinegar extract showed excellent alcohol oxidation and was effective in hangover improvement.

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Inhibitory action of the natural product AP1700 on the withdrawal syndrome of nalbuphine Jongseok Kang ;Hunkyu Lee ;Donghyun Kim ;Hwan-soo Yoo ;Soyong Jang ;Seikwan Oh pp.13-19

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Isoliquiritigenin :a competitive tyrosinase inhibitor from the heartwood of Dalbergia odorifera Tai Hyun Kang ;Yu Hua Tian ;Youn Chul Kim pp.32-34

Effects of adenylate cyclase, guanylate cyclase and K_ATP_ channel blockade on the cerebral blood flow response induced by adenosine A_2B_ receptor agonist in the rats Doo Sang Youn ;In Chul Shin pp.35-40

The effect of oak wood vinegar extract on blood alcohol concentration and hangover syndrome Young In Choi ;Jin Soo Kwon ;Yoon Seok Song ;Sung Ho Wang pp.41-47

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참고문헌 (6건) : 자료제공( 네이버학술정보 )

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번호 참고문헌 국회도서관 소장유무
1 Comparison of Hepatic Detox-ification activity and reducing Serum Alcohol concnetration of Hovenia dulsis THUNB and Alnus japonica Steud. Korean J. Medicinal Crop Sci. 7, 미소장
2 Observations on transimination in liver homogenates 네이버 미소장
3 (1999) . Cause and effect of hangover. Food Ind. Nur. 4, 미소장
4 (1992) . Alcohol and liver. In Medi-cal and nutritional complications of alcoholims, pp 185. Plenum Medical Book Co 미소장
5 (1994) . Ethanol oxidation is accelerated by augmenta-tion of malate-aspartate shuttle with aspartate. Korean J. Bio-chem. 25, 미소장
6 (1999) Removal method of harmful ingredient that is included to wood vinegar. Korean Industrial Property, 미소장