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국회도서관 홈으로 정보검색 소장정보 검색

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Title Page

Abstract

Contents

Introduction 7

Material and methods 9

Cell lines and hypoxic culture conditions 9

Culture conditions 9

Gel zymography to show uPA activity 10

Western blot analysis to show uPAR, ERK, HIF-1a expression 10

Drug treatment 11

Results 12

Hypoxia increased expression of HIF-1a, uPAR and ERK phosphorylation in the MDA-MB-231 cell line 12

ERK modulates uPAR expression in hypoxic MDA-MB-231 cells 12

iNOS inhibitor increased ERK phosphorylation and modulated uPAR expression under hypoxic conditions in the MDA-MB-231 cell line 12

HIF-1a expression was increased after SNP treatment and decreased after iNOS inhibitor treatment 13

Discussion 14

Conclusion 17

References 18

도표 및 그림 25

챗봇 챗봇