본문 바로가기 주메뉴 바로가기
22대 대한민국 국회 국회정보길라잡이 국회의원검색
회원가입 로그인
HOME

정보검색

소장정보 검색

국회도서관 홈으로 정보검색 소장정보 검색

결과 내 검색

동의어 포함

고급검색

인명/단체명

저자정보 상세정보
인명/단체명을 입력하세요.

키워드

  • 대표어

  • 외국어

-

목차보기

title page

ACKNOWLEDGEMENTS

Contents

Abstract 9

I. INTRODUCTION 11

II. MATERIALS AND METHODS 14

1. Isolation and culture of MSCs 14

2. Preparation of 3-dimensional extracellular matrices produced by cardiac fibroblast 15

3. MSC Labeling 17

4. Transfection of pMT3-CRT 17

5. Myocardial Scar Generation and Cell Transplantation 18

6. Assays for cell adhesion and spreading 19

7. RNA interference 20

8. Histology and Immunohistochemistry 21

III. RESULTS 22

1. Isolation and characterization of phenotypic markers(marekers) of MSCs 22

2. Transduction of CRT gene into MSCs 23

3. Over-expression of CRT enhances attachment efficacy of MSCs 24

4. Preparation of cardiac fibroblast-derived 3D metrics and attachment of CRT-MSCs 25

5. Changes in levels of CRT affect the spreading of MSCs 26

6. CRT overexpression cause the enhancing effect on the focal adhesion complex 27

7. Change of CRT expression in MSCs enhances cell survival after transplantation 28

IV. DISCUSSION 30

V. CONCLUSION 33

REFERENCES 34

국문요약 41

List of figures

Figure 1. Immunocytochemical characterization of MSCs… 23

Figure 2. Expression levels of CRT of control, GFP only and GFP-labeled CRT… 24

Figure 3. CRT dependent adhesion of MSCs on fibronectin coated plates… 25

Figure 4. A. Cardiac fibroblast-derived 3-D matrix before and after extraction… 26

Figure 5. CRT-induced spreading of MSCs… 27

Figure 6. Effect of CRT-overexpression on the adhesion-related signals in MSCs… 28

Figure 7. Analysis of myocardial repair after MSCs injection into LAD ligation-injured hearts… 29

추천서가 (다양한 추천 자료를 만나보세요)

권호기사보기

권호기사 목록 테이블로 기사명, 저자명, 페이지, 원문, 기사목차 순으로 되어있습니다.
기사명 저자명 페이지 원문 기사목차

권호

기사명 원문보기 기사목차
닫기