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정보검색

소장정보 검색

국회도서관 홈으로 정보검색 소장정보 검색
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결과 내 검색 동의어 포함

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Contents

Introduction 9

Objective 11

Materials and Methods 12

Animals 12

Radiofrequency Procedure 13

Study Groups 14

Phase 1: 0.5 ㎝ (group A) vs. 1.0 ㎝ (group B) safe distance 16

Phase 2: vertical vs. parallel direction of electrode to the GB wall 16

Phase 3: immediate vs. acute phase 17

Analysis of GB wall injury 19

I. Gross Pathologic Analysis 19

II. Histopathologic Analysis 19

Statistical Analysis 21

Results 22

I. Gross Changes of the GB Wall 22

Phase 1: 0.5 ㎝ (group A) vs. 1.0 ㎝ (group B) safe distance 22

Phase 2: vertical vs. parallel direction of electrode to the GB wall 26

Phase 3: immediate vs. acute phase 26

II. Microscopic Changes of the GB Wall 27

A. Depth of Thermal Injury of the GB Wall 27

Phase 1: 0.5 ㎝ (group A) vs. 1.0 ㎝ (group B) safe distance 27

Phase 2: vertical or parallel direction of electrode to the GB wall 31

Phase 3: immediate vs. acute phase 31

B. Variables of Abnormal Microscopic Changes of GB Mucosa 33

Discussion 36

Conclusion 42

References 43

English Abstracts 50

Korean Abstracts 53

Legends of Tables

Table 1. The Number of RF Ablation Zones Created in 15 Pigs Liver according to Three Phases 15

Table 2. Gross Changes of Gallbladder Wall Adjacent to Pig Liver after RF Ablation without Safe Distance (Group A) and with Safe Distance (Group B) Based on Electrode Direction and Time of Sacrifice. 23

Table 3. The Depth of Thermal Injury of Abutting Gallbladder Wall adjacent to Ablation Zones in Pig Liver without Safe Distance (Group A) and with Safe Distance (Group B) Based on Electrode Direction and Time of Sacrifice. 32

Table 4. The Grade of Microscopic Changes found in Gallbladder Mucosa adjacent to Ablation Zones Created in Pig Livers after RF Ablation without Safe Distance (Group A) and with Safe Distance (Group B) 34

Legends of Figures

Figure 1. The method of electrode direction to the GB in a pig liver. 18

Figure 2. Photographs of the specimens extracted from the group A pig immediately after RF ablation with parallel direction (group Ai and Ap). 24

Figure 3. Photographs of the specimens extracted from group A pig seven days following RF ablation with parallel direction (group Aa and Ap).... 25

Figure 4. Photomicrographs of resected GB immediately following RF ablation with parallel direction in no safe distance group (group Ai and Ap).... 28

Figure 5. Photomicrographs of resected GB seven days following RF ablation with parallel direction in safe distance group (group Ba and Bp).... 29

Figure 6. Photomicrographs of resected GB immediately following RF ablation with parallel direction in no safe distance group (group Ai and Ap).... 30

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