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국회도서관 홈으로 정보검색 소장정보 검색

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Title Page 2

Contents 6

Abstract 7

Introduction 13

Current research trends 21

Research Methods 25

1. Cell lines, cell culture conditions 25

2. In vitro invasion and migration assays 26

3. Immunoblot analysis 27

4. siRNAs transfection 27

5. Reverse Transcriptase (RT)-PCR 28

6. Chromatin Immunoprecipitation (ChIP) assay 29

7. Real Time (RT)-qPCR 30

8. Co-immunoprecipitation (Co-IP) Assay 31

9. Analysis of breast cancer databases 32

10. Chemical treatment 32

11. Statistical analysis 33

Results and discussion 34

Section Ⅰ. The Role of CCL8 in Triple-Negative Breast Cancer (TNBC) Aggressiveness 34

Section Ⅱ. The Role of CRP in Triple-Negative Breast Cancer (TNBC) Aggressiveness 64

Discussion and Conclusion 92

Section Ⅰ. The Role of CCL8 in Triple-Negative Breast Cancer (TNBC) Aggressiveness 92

Section Ⅱ. The Role of CRP in Triple-Negative Breast Cancer (TNBC) Aggressiveness 94

References 97

국문 초록 103